Valproate Dosage and Serum Levels

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How often can the dosage of valproate be increased?

Every 3 days

What is the initial dosage of valproate when the treatment is started?

250 mg three times daily

What is the typical daily dosage range of valproate for most patients?

1,250–2,500 mg

When can serum levels of valproate be obtained?

After 3–4 days

How much can the dosage of valproate be increased at a time?

250 mg

What is the initial frequency of carbamazepine administration?

Twice daily

After how many days is the frequency of carbamazepine administration increased?

3–5 days

What is the target range for anticonvulsant blood levels of carbamazepine?

8–12!g/mL

What is the typical daily dosage range of carbamazepine for most patients?

600–1,600 mg/day

Has a dose-response curve been established for carbamazepine?

No, a dose-response curve has not been established

Learn about the initial dosage and titration of valproate, a medication commonly used to treat epilepsy and bipolar disorder. Understand how to monitor serum levels and achieve optimal therapeutic doses.

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