33 Questions
A mature virus particle containing a nucleic acid core surrounded by a protein coat, with or without envelope, is called:
Virion
Viruses are characterized by the presence of:
DNA and RNA
What is the largest DNA virus?
Poxvirus
Which of the following is the smallest RNA virus?
Enterovirus
What is the first step in the replication cycle of a virus?
Attachment and penetration
The virus capsid morphology is:
Helical or icosahedral
From what part of the virus is the envelope acquired?
Nuclear or cytoplasmic membrane
Where is the site o virion assembly?
Nucleus or cytoplasm
Which of the following is DNA virus?
Herpesviridae
Which of the following is an RNA virus?
Pseudomyxoviridae
Specimens collected for virus isolation should be kept at:
4C
At what temperature should clinical specimens suspected of containing viruses kept for transport that takes days?
-70C
In what family of viruses, after primary infection, does an individual become latently infected and then the infection can be reactivated?
Herpesviridae
Cytomegalovirus isolation is best accomplished using:
Human embryonic fibroblasts
Which of the following viruses causes acute central nervous system disease in humans and animals?
Rabies
What specimen/s should be collected from a patient with suspected enteroviral meningitis?
AOTA
Influenza A viruses can be detected in cell cultures by:
Hemadsorption assay
The best host systems for influenza virus isolation are:
Monkey kidney cells and embryonated hen's eggs
What common antigen is cross-reactive in all human adenoviruses?
Hexon
The following characteristics are similar in both influenza and parainfluenza viruses, except:
Segmented RNA genome
Myxoviridae virus envelope contains both:
Neuraminidase and hemagglutinin
Eosinophilic cytoplasmic inclusions are elementary bodies of the:
Poxvirus
German measles is caused by:
Rubella virus
What is an alastrim infection?
Mild form of smallpox
Which of the following laboratory procedures is routinely used for the detection of hepatitis B virus (HBV) in blood donors?
A and B
Which of the following laboratory procedures is the most rapid method for diagnosis of a virus infection?
Direct electron microscopy
What specimen/s should be collected from a patient with suspected influenza?
Throat swab
What virus group contains a double stranded, segmented RNA genome?
Reovirus
Enteroviruses can be differentiated from rhinoviruses by:
Acid resistance
What virus is the most frequent cause of gastroenteritis in children during the winter months?
Rotavirus
All of the following groups of viruses are resistant to ether treatment, except:
Herpesviruses
The most common method for rapid electron microscopy examination is:
Negative staining
Various virus groups can be differentiated in negatively stained specimens by their:
Morphology
Test your knowledge on virus structure, characteristics, and replication cycles. Questions cover virus morphology, DNA and RNA viruses, and steps in the replication process.
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