APLN - VIROLOGY
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Questions and Answers

A mature virus particle containing a nucleic acid core surrounded by a protein coat, with or without envelope, is called:

  • Nucleocapsid
  • Genome
  • Virion (correct)
  • Capsomer
  • Viruses are characterized by the presence of:

  • Mitochondrial DNA
  • DNA and RNA (correct)
  • Ribosomal RNA
  • RNA
  • What is the largest DNA virus?

  • Herpesvirus
  • Poxvirus (correct)
  • Adenovirus
  • Parvovirus
  • Which of the following is the smallest RNA virus?

    <p>Enterovirus</p> Signup and view all the answers

    What is the first step in the replication cycle of a virus?

    <p>Attachment and penetration</p> Signup and view all the answers

    The virus capsid morphology is:

    <p>Helical or icosahedral</p> Signup and view all the answers

    From what part of the virus is the envelope acquired?

    <p>Nuclear or cytoplasmic membrane</p> Signup and view all the answers

    Where is the site o virion assembly?

    <p>Nucleus or cytoplasm</p> Signup and view all the answers

    Which of the following is DNA virus?

    <p>Herpesviridae</p> Signup and view all the answers

    Which of the following is an RNA virus?

    <p>Pseudomyxoviridae</p> Signup and view all the answers

    Specimens collected for virus isolation should be kept at:

    <p>4C</p> Signup and view all the answers

    At what temperature should clinical specimens suspected of containing viruses kept for transport that takes days?

    <p>-70C</p> Signup and view all the answers

    In what family of viruses, after primary infection, does an individual become latently infected and then the infection can be reactivated?

    <p>Herpesviridae</p> Signup and view all the answers

    Cytomegalovirus isolation is best accomplished using:

    <p>Human embryonic fibroblasts</p> Signup and view all the answers

    Which of the following viruses causes acute central nervous system disease in humans and animals?

    <p>Rabies</p> Signup and view all the answers

    What specimen/s should be collected from a patient with suspected enteroviral meningitis?

    <p>AOTA</p> Signup and view all the answers

    Influenza A viruses can be detected in cell cultures by:

    <p>Hemadsorption assay</p> Signup and view all the answers

    The best host systems for influenza virus isolation are:

    <p>Monkey kidney cells and embryonated hen's eggs</p> Signup and view all the answers

    What common antigen is cross-reactive in all human adenoviruses?

    <p>Hexon</p> Signup and view all the answers

    The following characteristics are similar in both influenza and parainfluenza viruses, except:

    <p>Segmented RNA genome</p> Signup and view all the answers

    Myxoviridae virus envelope contains both:

    <p>Neuraminidase and hemagglutinin</p> Signup and view all the answers

    Eosinophilic cytoplasmic inclusions are elementary bodies of the:

    <p>Poxvirus</p> Signup and view all the answers

    German measles is caused by:

    <p>Rubella virus</p> Signup and view all the answers

    What is an alastrim infection?

    <p>Mild form of smallpox</p> Signup and view all the answers

    Which of the following laboratory procedures is routinely used for the detection of hepatitis B virus (HBV) in blood donors?

    <p>A and B</p> Signup and view all the answers

    Which of the following laboratory procedures is the most rapid method for diagnosis of a virus infection?

    <p>Direct electron microscopy</p> Signup and view all the answers

    What specimen/s should be collected from a patient with suspected influenza?

    <p>Throat swab</p> Signup and view all the answers

    What virus group contains a double stranded, segmented RNA genome?

    <p>Reovirus</p> Signup and view all the answers

    Enteroviruses can be differentiated from rhinoviruses by:

    <p>Acid resistance</p> Signup and view all the answers

    What virus is the most frequent cause of gastroenteritis in children during the winter months?

    <p>Rotavirus</p> Signup and view all the answers

    All of the following groups of viruses are resistant to ether treatment, except:

    <p>Herpesviruses</p> Signup and view all the answers

    The most common method for rapid electron microscopy examination is:

    <p>Negative staining</p> Signup and view all the answers

    Various virus groups can be differentiated in negatively stained specimens by their:

    <p>Morphology</p> Signup and view all the answers

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