APLN - VIROLOGY

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Questions and Answers

A mature virus particle containing a nucleic acid core surrounded by a protein coat, with or without envelope, is called:

  • Nucleocapsid
  • Genome
  • Virion (correct)
  • Capsomer

Viruses are characterized by the presence of:

  • Mitochondrial DNA
  • DNA and RNA (correct)
  • Ribosomal RNA
  • RNA

What is the largest DNA virus?

  • Herpesvirus
  • Poxvirus (correct)
  • Adenovirus
  • Parvovirus

Which of the following is the smallest RNA virus?

<p>Enterovirus (D)</p> Signup and view all the answers

What is the first step in the replication cycle of a virus?

<p>Attachment and penetration (A)</p> Signup and view all the answers

The virus capsid morphology is:

<p>Helical or icosahedral (D)</p> Signup and view all the answers

From what part of the virus is the envelope acquired?

<p>Nuclear or cytoplasmic membrane (A)</p> Signup and view all the answers

Where is the site o virion assembly?

<p>Nucleus or cytoplasm (B)</p> Signup and view all the answers

Which of the following is DNA virus?

<p>Herpesviridae (C)</p> Signup and view all the answers

Which of the following is an RNA virus?

<p>Pseudomyxoviridae (A)</p> Signup and view all the answers

Specimens collected for virus isolation should be kept at:

<p>4C (C)</p> Signup and view all the answers

At what temperature should clinical specimens suspected of containing viruses kept for transport that takes days?

<p>-70C (A)</p> Signup and view all the answers

In what family of viruses, after primary infection, does an individual become latently infected and then the infection can be reactivated?

<p>Herpesviridae (B)</p> Signup and view all the answers

Cytomegalovirus isolation is best accomplished using:

<p>Human embryonic fibroblasts (C)</p> Signup and view all the answers

Which of the following viruses causes acute central nervous system disease in humans and animals?

<p>Rabies (A)</p> Signup and view all the answers

What specimen/s should be collected from a patient with suspected enteroviral meningitis?

<p>AOTA (D)</p> Signup and view all the answers

Influenza A viruses can be detected in cell cultures by:

<p>Hemadsorption assay (B)</p> Signup and view all the answers

The best host systems for influenza virus isolation are:

<p>Monkey kidney cells and embryonated hen's eggs (A)</p> Signup and view all the answers

What common antigen is cross-reactive in all human adenoviruses?

<p>Hexon (B)</p> Signup and view all the answers

The following characteristics are similar in both influenza and parainfluenza viruses, except:

<p>Segmented RNA genome (D)</p> Signup and view all the answers

Myxoviridae virus envelope contains both:

<p>Neuraminidase and hemagglutinin (A)</p> Signup and view all the answers

Eosinophilic cytoplasmic inclusions are elementary bodies of the:

<p>Poxvirus (B)</p> Signup and view all the answers

German measles is caused by:

<p>Rubella virus (B)</p> Signup and view all the answers

What is an alastrim infection?

<p>Mild form of smallpox (C)</p> Signup and view all the answers

Which of the following laboratory procedures is routinely used for the detection of hepatitis B virus (HBV) in blood donors?

<p>A and B (D)</p> Signup and view all the answers

Which of the following laboratory procedures is the most rapid method for diagnosis of a virus infection?

<p>Direct electron microscopy (C)</p> Signup and view all the answers

What specimen/s should be collected from a patient with suspected influenza?

<p>Throat swab (B)</p> Signup and view all the answers

What virus group contains a double stranded, segmented RNA genome?

<p>Reovirus (D)</p> Signup and view all the answers

Enteroviruses can be differentiated from rhinoviruses by:

<p>Acid resistance (A)</p> Signup and view all the answers

What virus is the most frequent cause of gastroenteritis in children during the winter months?

<p>Rotavirus (C)</p> Signup and view all the answers

All of the following groups of viruses are resistant to ether treatment, except:

<p>Herpesviruses (A)</p> Signup and view all the answers

The most common method for rapid electron microscopy examination is:

<p>Negative staining (A)</p> Signup and view all the answers

Various virus groups can be differentiated in negatively stained specimens by their:

<p>Morphology (C)</p> Signup and view all the answers

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