schitozophrenia

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Questions and Answers

Which dopamine pathway is associated with positive symptoms of schizophrenia?

Mesocortical pathway
Tuberoinfundibular pathway
Mesolimbic pathway (correct)
Nigrostriatal pathway

What negative symptoms of schizophrenia are linked to the meso-cortical dopamine system?

Disorganized thinking
Hallucinations
Delusions
Affective flattening (correct)

What evidence supports the dopamine hypothesis in relation to antipsychotic medications?

They primarily increase serotonin levels.
They have no side effects.
They block D2 dopamine receptors. (correct)
They enhance the effects of amphetamines.

What is the function of the nigrostriatal pathway?

Modulates voluntary movement control (A) Signup and view all the answers

Which of the following is a side effect of drugs that block dopamine receptors?

Tremors (B) Signup and view all the answers

What is a characteristic of atypical antipsychotics?

They block receptors for both serotonin and dopamine. (D) Signup and view all the answers

How do amphetamines affect symptoms related to schizophrenia?

They cause schizophrenia-like symptoms. (C) Signup and view all the answers

What role do neurotransmitter interactions play in schizophrenia treatment?

They may enhance the effectiveness of atypical antipsychotics. (D) Signup and view all the answers

What is the primary neurotransmitter associated with the negative symptoms of schizophrenia?

Serotonin (A) Signup and view all the answers

Which of the following best explains the relationship between atypical antipsychotics and dopamine activity?

They have a low affinity for dopamine receptors. (D) Signup and view all the answers

Which brain structure is typically found to be smaller in individuals with schizophrenia?

Hippocampus (D) Signup and view all the answers

What effect does excess serotonin have on mood and behavior?

Leads to irritable mood and potential aggressive behavior. (A) Signup and view all the answers

Which brain circuit is NOT implicated in the disruption of schizophrenia?

Visual cortex (D) Signup and view all the answers

What percentage risk of developing schizophrenia is associated with having both parents affected?

35% (C) Signup and view all the answers

What is one of the primary characteristics of the dopamine hypothesis in relation to schizophrenia?

Decreased dopamine leads to negative symptoms. (A) Signup and view all the answers

Which receptor's stabilization is highlighted as beneficial for perceptions of reality in schizophrenia treatment?

5HT2a receptor (C) Signup and view all the answers

What are considered positive symptoms of schizophrenia?

Delusions (A) Signup and view all the answers

Which symptom is classified as a negative symptom of schizophrenia?

Flat affect (D) Signup and view all the answers

What is the primary neurobiological factor believed to contribute to positive symptoms of schizophrenia?

Increased numbers of D2 dopamine receptors (C) Signup and view all the answers

Which class of medication is typically more effective for treating negative symptoms of schizophrenia?

Atypical antipsychotics (B) Signup and view all the answers

What characterizes the onset of negative symptoms in schizophrenia compared to positive symptoms?

Gradual onset (C) Signup and view all the answers

Which of the following statements about dopamine hypothesis in schizophrenia is accurate?

Positive symptoms are linked to increased D2 receptors. (A) Signup and view all the answers

Which symptom is not commonly associated with schizophrenia?

Increased sociability (D) Signup and view all the answers

What is the minimum duration for the continuous signs of schizophrenia to be diagnosed?

Six months (D) Signup and view all the answers

Flashcards

Mesolimbic pathway

Dopamine pathway associated with positive symptoms of schizophrenia.

Affective flattening

Negative symptom of schizophrenia linked to the meso-cortical dopamine system.