Urinary Tract Infections (UTI) - Definitions and Concepts

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Questions and Answers

What is the definition of UTI?

  • The presence of WBCs in the urine
  • The presence of bacteria in the urine without symptoms
  • A complication of diabetes mellitus
  • A constellation of symptoms resulting from an inflammatory response of the urothelium to bacterial invasion (correct)

What is bacteriuria?

  • A type of complicated UTI
  • A type of sterile pyuria
  • The presence of bacteria in the urine, which may be asymptomatic or symptomatic (correct)
  • The presence of WBCs in the urine

What is pyuria?

  • A type of renal stone
  • The presence of bacteria in the urine
  • A type of urinary tract infection
  • The presence of WBCs in the urine, implying an inflammatory response (correct)

What is an uncomplicated UTI?

<p>A UTI occurring in a patient with a structurally and functionally normal urinary tract (B)</p> Signup and view all the answers

What is a complicated UTI?

<p>A UTI occurring in a patient with a structurally and functionally abnormal urinary tract (A)</p> Signup and view all the answers

Which of the following is a factor suggesting a potential complicated UTI?

<p>All of the above (D)</p> Signup and view all the answers

What is the main difference between complicated and uncomplicated UTIs?

<p>Complicated UTIs take longer to respond to antibiotic treatment (A)</p> Signup and view all the answers

What is the definition of an isolated UTI?

<p>An interval of at least 6 months between infections (D)</p> Signup and view all the answers

What is the most common bacterial pathogen causing UTI?

<p>E. coli (B)</p> Signup and view all the answers

What is the prevalence of UTI in women?

<p>Around 50% of women experience one or more episodes in their lifetime (D)</p> Signup and view all the answers

What is the incidence of UTI in women per year?

<p>3% per year (A)</p> Signup and view all the answers

What is the route of infection for the vast majority of UTIs?

<p>Ascending from the urethra (A)</p> Signup and view all the answers

What is the mechanism by which certain Gram-negative bacteria, such as E. coli, attach to urothelial cells?

<p>Pili (fimbriae) (D)</p> Signup and view all the answers

Which of the following is a common symptom of cystitis?

<p>Suprapubic pain (B)</p> Signup and view all the answers

What is the purpose of including a pelvic examination in women during the investigation of UTI?

<p>To assess for atrophic vaginitis, prolapse, and urethral diverticulum (A)</p> Signup and view all the answers

What does leucocyte esterase activity detect in a dipstick test?

<p>White blood cells (A)</p> Signup and view all the answers

What is the term for bacteria that enter the urinary tract through the bloodstream?

<p>Haematogenous (D)</p> Signup and view all the answers

What is the term for infection and/or inflammation of the bladder?

<p>Cystitis (B)</p> Signup and view all the answers

What is the definition of pyelonephritis?

<p>Inflammation of the kidney and renal pelvis (A)</p> Signup and view all the answers

What percentage of infections are secondary to E. coli?

<p>80% (B)</p> Signup and view all the answers

What is a common symptom of upper urinary tract infection?

<p>Flank pain and fever (C)</p> Signup and view all the answers

What is a possible cause of retrograde bacterial ascent from bladder to kidney?

<p>Obstruction that interferes with ureteric peristalsis (C)</p> Signup and view all the answers

When should further investigations be undertaken?

<p>All of the above (D)</p> Signup and view all the answers

What imaging modality is used to investigate upper urinary tract infection?

<p>USS (or CT if suspecting stones) (C)</p> Signup and view all the answers

In patients with a fever but no signs of systemic illness, what is the recommended management approach?

<p>Outpatient management with oral antibiotics (C)</p> Signup and view all the answers

What is the first-line antibiotic treatment for urinary tract infections, assuming E. coli resistance is below 38%?

<p>Ciprofloxacin 500mg bd for 7–10 days (B)</p> Signup and view all the answers

What is a common cause of urinary sepsis?

<p>Presence or manipulation of indwelling urinary catheters (D)</p> Signup and view all the answers

What is the pathogenesis of epididymitis?

<p>Infection ascends from the urethra or bladder (B)</p> Signup and view all the answers

In which patient group is epididymitis commonly seen?

<p>Sexually active men (C)</p> Signup and view all the answers

What is the term for an inflammatory condition of the epididymis and testis?

<p>Epididymo-orchitis (C)</p> Signup and view all the answers

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