Urinary System Quiz
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Questions and Answers

What is the main function of the urinary system?

  • Regulation of body temperature
  • Production of hormones
  • Excretion of waste products (correct)
  • Digestion of food
  • The right kidney is located higher than the left kidney.

    False (B)

    What is the approximate size and shape of a kidney?

    Bean-shaped, about 11 cm long, 6 cm wide, and 3 cm thick

    The functional unit of the kidney is called the __________.

    <p>nephron</p> Signup and view all the answers

    Match the following kidney structures with their functions:

    <p>Renal hilum = Entry/exit point for blood vessels and ureter Adipose capsule = Protection and cushioning for the kidney Renal fascia = Anchors kidney to surrounding structures Nephron = Functional unit of the kidney</p> Signup and view all the answers

    What condition is described as an inferior displacement of the kidneys?

    <p>Nephroptosis (A)</p> Signup and view all the answers

    The kidney's role includes regulating blood volume and blood pressure.

    <p>True (A)</p> Signup and view all the answers

    What is found in the urine that kidneys produce?

    <p>Carbon dioxide, ammonia, urea, uric acid, creatinine, and inorganic salts</p> Signup and view all the answers

    What is the main function of diuretics?

    <p>Increase urine flow rate (C)</p> Signup and view all the answers

    The urinary bladder has a capacity of approximately 500-600 mL.

    <p>False (B)</p> Signup and view all the answers

    What triggers the micturition reflex when the bladder fills?

    <p>Stretch receptors send signals to the micturition center in the spinal cord.</p> Signup and view all the answers

    The __________ is the triangular area formed by the openings in the floor of the urinary bladder.

    <p>trigone</p> Signup and view all the answers

    Match the following structures with their functions:

    <p>Ureters = Transport urine from kidneys to bladder Urinary Bladder = Stores urine Loop of Henle = Concentrates urine Detrusor muscle = Expels urine</p> Signup and view all the answers

    Which hormone increases the reabsorption of water in the kidneys?

    <p>Antidiuretic hormone (ADH) (B)</p> Signup and view all the answers

    The inner lining of the bladder, when empty, is arranged in folds called rugae.

    <p>True (A)</p> Signup and view all the answers

    The contraction of the __________ muscle in the bladder is responsible for expelling urine.

    <p>detrusor</p> Signup and view all the answers

    What is the normal bladder capacity?

    <p>600 mls (A)</p> Signup and view all the answers

    The female urethra is longer than the male urethra.

    <p>False (B)</p> Signup and view all the answers

    What triggers the micturition reflex?

    <p>Accumulation of urine in the bladder</p> Signup and view all the answers

    The ________ sphincter is a smooth involuntary muscle at the beginning of the urethra.

    <p>internal urethral</p> Signup and view all the answers

    Match the following conditions with their definitions:

    <p>Urethritis = Infection of the urethra Cystitis = Infection of the urinary bladder Temporary incontinence = Loss of bladder control due to weakened muscles Permanent incontinence = Inability to control urination due to damage</p> Signup and view all the answers

    What is a common cause for urinary tract infections (UTIs) in women?

    <p>Shorter urethra (D)</p> Signup and view all the answers

    Micturition can only happen voluntarily.

    <p>False (B)</p> Signup and view all the answers

    What might cause temporary urinary incontinence?

    <p>Weakening of muscles around the bladder and urethra</p> Signup and view all the answers

    What percentage of solute reabsorption occurs in the proximal convoluted tubule?

    <p>65% (C)</p> Signup and view all the answers

    The ascending limb of the nephron loop is permeable to water.

    <p>False (B)</p> Signup and view all the answers

    What hormone is responsible for increasing the reabsorption of water in the DCT and collecting duct?

    <p>Antidiuretic hormone (ADH)</p> Signup and view all the answers

    Reabsorption of sodium and water is increased by __________, which is secreted by the adrenal cortex.

    <p>Aldosterone</p> Signup and view all the answers

    Match the following hormones with their actions:

    <p>Parathyroid hormone = Regulates reabsorption of Ca2+ and phosphate Aldosterone = Increases reabsorption of Na+ and water Antidiuretic hormone (ADH) = Increases water reabsorption Atrial natriuretic peptide (ANP) = Decreases reabsorption of Na+ and water</p> Signup and view all the answers

    What happens when there is a high concentration of solutes in the blood?

    <p>The kidneys secrete a small amount of concentrated urine. (B)</p> Signup and view all the answers

    Secretion in the kidneys helps control blood pH.

    <p>True (A)</p> Signup and view all the answers

    What role does negative feedback play in the secretion of aldosterone?

    <p>It helps regulate the levels of Na+ and K+ in the blood.</p> Signup and view all the answers

    What is the main function of the renal tubule?

    <p>All of the above (D)</p> Signup and view all the answers

    Less than 1% of the filtrate produced daily becomes urine.

    <p>True (A)</p> Signup and view all the answers

    What is the composition of the filtrate produced during filtration?

    <p>Water, ions, and small molecules</p> Signup and view all the answers

    The _____ is responsible for the movement of fluid from the glomerular capillary across the filtration membrane.

    <p>filtration pressure</p> Signup and view all the answers

    Match the following pressures with their contributions to filtration:

    <p>GCP = Blood pressure inside the capillary CHP = Pressure of filtrate in the lumen BCOP = Osmotic pressure caused by proteins in blood Filtration Pressure = Pressure gradient responsible for filtration</p> Signup and view all the answers

    Which of the following substances are NOT typically filtered into the nephron?

    <p>Plasma proteins (A)</p> Signup and view all the answers

    Capsular hydrostatic pressure (CHP) tends to facilitate the movement of fluid into the Bowman’s capsule.

    <p>False (B)</p> Signup and view all the answers

    How much filtrate is produced daily by the kidneys?

    <p>150-180 liters</p> Signup and view all the answers

    What is the outer light-red region of the kidney called?

    <p>Renal cortex (B)</p> Signup and view all the answers

    The renal pyramids are located in the renal cortex.

    <p>False (B)</p> Signup and view all the answers

    What is the primary function of nephrons in the kidney?

    <p>Filtration and regulation of urine formation</p> Signup and view all the answers

    The cavity that collects urine from the major calyx is called the __________.

    <p>renal pelvis</p> Signup and view all the answers

    Match the kidney structures with their descriptions:

    <p>Renal corpuscle = The part of the nephron where blood filtration occurs Renal tubule = The part of the nephron responsible for reabsorption and secretion Minor calyx = Surrounds renal papillae and collects urine from pyramids Renal artery = The blood vessel that supplies blood to the kidney</p> Signup and view all the answers

    Where do nephrons receive their blood supply from?

    <p>Renal artery (C)</p> Signup and view all the answers

    Nephrons can be replaced if damaged.

    <p>False (B)</p> Signup and view all the answers

    What does the renal plexus supply to the kidney?

    <p>Nerve supply (sympathetic division of the Autonomic Nervous System)</p> Signup and view all the answers

    Flashcards

    Nephron

    The functional unit of the kidney.

    Renal Corpuscle

    Part of a nephron that filters blood.

    Renal Tubule

    Part of a nephron that reabsorbs and secretes substances.

    Renal Cortex

    Outer layer of the kidney, light-red in color.

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    Renal Medulla

    Darker inner layer of kidney.

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    Renal Pyramid

    A cone-shaped structure inside the renal medulla.

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    Renal Pelvis

    The cavity that collects urine from the kidney.

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    Ureter

    Tube that carries urine from kidney to bladder.

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    Urinary System Function

    The main excretory system that maintains water and electrolyte balance in the body by removing waste products from the blood; it regulates blood volume, pressure, solute concentrations, pH, and red blood cell and vitamin D synthesis.

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    Kidney Location

    Located behind the peritoneum, on either side of the vertebral column, between the 12th thoracic and 3rd lumbar vertebrae. The right kidney is slightly lower than the left, because of the liver's position.

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    Kidney Structure

    Bean-shaped organs consisting of a cortex and medulla; the functional portion, or parenchyma of the kidney.

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    Urine Composition

    Urine contains waste products such as carbon dioxide, ammonia, urea, uric acid, creatinine, and inorganic salts.

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    Renal hilum

    An indented area on the kidney where the renal artery, nerves, renal vein, and ureter enter and exit.

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    Nephroptosis

    Inferior displacement of the kidneys, potentially causing ureter kinking and urine flow blockage.

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    Kidney Functions

    Excretion of waste; regulation of blood volume, pressure, solute concentrations, pH and red blood cell and vitamin D synthesis.

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    Filtration

    The process where fluid from blood in the glomerulus moves across the filtration membrane into Bowman's capsule.

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    Filtrate

    The fluid that is formed during filtration, containing water, ions, and small molecules.

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    What substances are NOT filtered?

    Large molecules like plasma proteins, blood cells, and platelets are too big to pass through the filtration membrane.

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    Filtration Pressure

    The pressure difference that drives filtration, forcing fluid from the glomerular capillary into Bowman's capsule.

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    Glomerular Capillary Pressure (GCP)

    The blood pressure inside the glomerular capillary, pushing fluid out into Bowman's capsule.

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    Capsular Hydrostatic Pressure (CHP)

    The pressure of the filtrate already in Bowman's capsule, resisting further filtration.

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    Blood Colloid Osmotic Pressure (BCOP)

    The pressure caused by proteins in the blood, pulling fluid back into the capillary.

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    Glomerular Filtration Rate (GFR)

    The volume of filtrate formed by both kidneys per minute.

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    Reabsorption in Nephron

    The process of recovering useful substances from the filtrate back into the bloodstream. It occurs throughout the renal tubule, with different segments responsible for absorbing specific substances.

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    Proximal Convoluted Tubule (PCT)

    The first segment of the renal tubule where the majority of reabsorption occurs (around 65%). It absorbs essential nutrients, water, and electrolytes from the filtrate.

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    Secretion in Nephron

    The process of removing waste products and excess substances from the blood and releasing them into the renal tubules for excretion in urine.

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    Parathyroid Hormone (PTH)

    A hormone secreted by the parathyroid gland that regulates the reabsorption of calcium and phosphate in the distal convoluted tubule (DCT) to maintain blood calcium levels.

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    Aldosterone

    A hormone secreted by the adrenal cortex that increases the reabsorption of sodium and water and promotes potassium secretion in the DCT, thus regulating blood volume and pressure.

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    Antidiuretic Hormone (ADH)

    A hormone secreted by the posterior pituitary that increases water reabsorption in the collecting duct, reducing urine volume and maintaining blood pressure.

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    Atrial Natriuretic Peptide (ANP)

    A hormone secreted from the heart's right atrium when blood pressure is high. It decreases sodium and water reabsorption in the proximal convoluted tubule (PCT) and collecting ducts, helping to reduce blood pressure.

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    Urine Concentration & Dilution

    The kidney's ability to adjust the volume and osmolality (concentration) of urine based on the body's needs. It concentrates urine when the body is dehydrated and dilutes urine when the body is hydrated.

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    Internal Urethral Sphincter

    A ring of smooth muscle at the beginning of the urethra that controls urine flow from the bladder (involuntary).

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    External Urethral Sphincter

    A ring of skeletal muscle that encircles the urethra where it passes through the pelvic floor (voluntary).

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    Micturition Reflex

    The involuntary process of urination triggered by bladder distension.

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    Bladder Capacity

    The maximum amount of urine the bladder can hold, typically around 600 ml, with the urge to urinate coming around 300-400 ml.

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    Urinary Incontinence

    The inability to control urination, leading to involuntary urine leakage.

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    Urethritis

    Inflammation of the urethra, often caused by infection.

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    Cystitis

    Inflammation of the urinary bladder, often caused by infection.

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    Diluted Urine Formation

    When low ADH is present, the collecting duct and late distal convoluted tubule become less permeable to water, resulting in more water reabsorption from the tubular fluid, leading to dilute urine.

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    Concentrated Urine Formation

    High ADH levels increase water permeability in the collecting duct and late distal convoluted tubule, leading to increased water reabsorption into the interstitial fluid. This results in less water remaining in the tubular fluid, leading to concentrated urine.

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    Diuretics Effect

    Drugs that increase urine flow rate by inhibiting specific transport mechanisms in the kidney, such as the symporters in the thick ascending limb of the loop of Henle, as seen with loop diuretics like furosemide.

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    Ureter Function

    Transports urine from the renal pelvis of the kidney to the urinary bladder, through peristaltic waves, hydrostatic pressure, and gravity.

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    Urinary Bladder Location

    A hollow, distensible muscular organ located in the pelvic cavity, below the parietal peritoneum, behind the symphysis pubis.

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    Micturition

    The act of urinating, involving a combination of voluntary and involuntary muscle contractions to expel urine from the bladder.

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    Trigone Definition

    A triangular area in the floor of the urinary bladder formed by three openings: two openings from the ureters and one opening into the urethra.

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    Detrusor Muscle Role

    Smooth muscle fibers that form the muscularis of the bladder, enabling the expulsion of urine upon contraction.

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    Study Notes

    Learning Outcomes

    • Students should be able to identify organs associated with the kidneys
    • Students should be able to state the functions of the kidneys
    • Students should be able to outline the gross structure of the kidneys
    • Students should be able to describe the structure of a nephron
    • Students should be able to explain urine formation
    • Students should be able to explain the structure of the ureter, urinary bladder, and urethra in the urinary system
    • Students should be able to explain the process of micturition

    Urinary System Overview

    • The urinary system is the main excretory system
    • It plays a vital role in maintaining water and electrolyte homeostasis
    • Urine contains carbon dioxide, ammonia, urea, uric acid, creatinine, and inorganic salts
    • The urinary system consists of two kidneys, two ureters, a urinary bladder, and a urethra

    Kidneys

    • Location: posterior abdominal wall, on each side of the vertebral column, extending from the 12th thoracic vertebra to the 3rd lumbar vertebra, behind the peritoneum, and below the diaphragm. The right kidney is slightly lower than the left due to the liver occupying space there.
    • Shape: bean-shaped organs, approximately 11 cm long, 6 cm wide, 3 cm thick and weigh 150 gm.
    • Gross structure: Renal hilum (where renal artery, nerves enter, and renal vein and ureter exit), renal sinus (cavity filled with fat and loose connective tissue), renal cortex (outer light-red region), renal medulla (darker red-brown inner region), renal pyramids (cone-shaped in the renal medulla), renal columns (extension of the renal cortex), renal papillae (base of renal pyramids pointing towards the center of the kidney), minor calyces (surround renal papillae, collecting urine from that pyramid), major calyces (formed from several minor calyces), renal pelvis (cavity collecting urine & continuous with the ureter)
    • Adipose capsule: protects the kidney from trauma and acts as cushioning
    • Renal fascia: thin layer of connective tissue anchoring the kidney to surrounding structures and abdominal wall

    Clinical Application: Nephroptosis

    • Nephroptosis is inferior displacement of the kidneys
    • More common in thin people
    • Dangerous because ureters may kink and block urine flow

    Microscopic Structure of the Kidney

    • Internally, kidneys consist of cortex, medulla, pyramids, papillae, columns, calyces, and renal pelvis
    • Renal cortex and renal pyramids constitute the functional portion or parenchyma of the kidney
    • Nephron: the functional unit of the kidney

    Nephron

    • Functional unit of the kidney
    • When damaged, they are not replaced
    • Consists of two parts: renal corpuscle and renal tubule
    • Functions: glomerular filtration, tubular reabsorption, tubular secretion

    Renal Corpuscle

    • Filters blood plasma
    • Located in the cortex of the kidney
    • Glomerulus: a network of tiny arterial capillaries
    • Glomerular (Bowman's) capsule: surrounds the glomerulus

    Renal Tubule

    • Carries filtered fluid away from the glomerular capsule
    • Consists of: Proximal convoluted tubule (PCT), Descending and ascending loop of Henle (nephron loop), Distal convoluted tubule (DCT)

    Clinical Application: Glomerulonephritis (GN)

    • Inflammatory condition of glomerulus
    • Impaired glomerular filtration
    • Symptoms include oliguria, hypertension, hematuria, and uraemia

    Clinical Application: Nephrotic Syndrome

    • Increased permeability of glomerular membrane resulting from glomerular damage
    • Plasma proteins pass into the filtrate
    • Symptom: edema

    Proximal Convoluted Tubule (PCT)

    • Arise from glomerular capsule
    • Filtrate passes first
    • Great absorption occurs here (glucose, amino acids, water, salts)

    Loop of Henle

    • A long U-shaped portion of the renal tubule
    • Contains descending limb and ascending limb
    • Active transport of salt

    Distal Convoluted Tubule (DCT)

    • Short & less coiled compared to the PCT
    • End of nephron

    Collecting Ducts

    • Receive fluids from the DCT of several nephrons
    • Fluid flows from collecting ducts into the minor calyces

    Juxtaglomerular Apparatus

    • Specialized structure near the glomerulus
    • Juxtaglomerular cells: ring of smooth muscle in the afferent arteriole where the latter enters Bowman's capsule; produce renin for blood pressure regulation
    • Macula densa: specialized tubule cells of the distal tubule that monitors sodium in the urine

    Overview of Renal Physiology (Urine Formation)

    • Glomerular filtration
    • Tubular reabsorption
    • Tubular secretion

    Filtration

    • Movement of fluid from blood through glomerulus across filtration membrane into the Bowman's capsule
    • Filtrate: Water, ions, and small molecules
    • Not filtered: Plasma proteins, blood cells, and platelets
    • Filtration pressure: pressure gradient responsible for filtration
    • Pressures contributing to filtration pressure: Glomerular capillary pressure (GCP), Capsular hydrostatic pressure (CHP), Blood colloid osmotic pressure (BCOP).
    • Glomerular filtration rate (GFR): the amount of filtrate formed in all the renal corpuscles of both kidneys each minute.

    Renal Autoregulation

    • Protect renal blood flow & glomerular filtration
    • Involves changes of constriction in afferent arterioles
    • Systemic blood pressure increases, afferent arterioles constrict and prevent increase in renal blood flow
    • Juxtaglomerular apparatus detects if there is increased rate of blood flow of filtrate past cells of macula densa, causing afferent arteriole constriction
    • In severe dehydration or hemorrhage, sympathetic simulation constricts small arteries & afferent arterioles, decreasing renal blood flow & filtrate formation. Renin, secreted from juxtaglomerular cells, stimulates vasoconstriction and maintains GFR.
    • Tubuloglomerular feedback: mechanisms used to maintain a consistent GFR (glomerular filtration rate).

    Reabsorption

    • Return of most filtered water and solutes to the bloodstream (about 99%)
    • Primarily in the PCT, the walls are lined with microvilli to increase surface area for absorption
    • Use active and passive processes
    • Sodium reabsorption is key to creating osmotic and electrical gradients for water reabsorption.

    Reabsorption...cont

    • Passive process: diffusion and osmosis
    • Active process: Using energy to transport molecules; carrier proteins bind to molecules
    • Reabsorption of glucose, amino acids, vitamins, minerals, and some H2O back into blood within PCT and DCT occur.
    • Location of reabsorption: 65% in proximal convoluted tubule, 15% in nephron loop, 19% in distal tubule, and 1% excreted as urine.
    • Most solutes are reabsorbed by active transport mechanism using carrier molecules.

    Secretion

    • Removing substances from blood into renal tubules
    • Helps control blood pH and eliminate substances from body
    • Takes place along the renal tubules and collecting ducts
    • Occurs via both passive diffusion and active transport

    Hormonal Actions

    • Parathyroid hormone: Secreted by parathyroid gland; works with calcitonin to regulate Ca2+ & phosphate reabsorption in the DCT to maintain blood levels.
    • Aldosterone: Secreted by the adrenal cortex; increased by renin action on angiotensin I converting to angiotensin II; increased reabsorption of Na+ and H2O, excretion of K+. Regulated via negative feedback mechanism
    • Antidiuretic hormone (ADH): Secreted by the anterior pituitary. Increases water reabsorption in the DCT and collecting duct; decreases urine volume and maintains normal blood volume and blood pressure
    • Atrial natriuretic peptide (ANP): Secreted from cardiac muscle in right atrium of the heart when BP increases; decreases reabsorption of Na+ and H2O in PCT and collecting ducts; regulated via negative feedback.

    Urine Concentration and Dilution

    • Kidneys change urine volume and osmolality by concentrating or diluting as per body needs
    • Hypothalamus: sensitive to blood composition
    • If solute concentration is high, kidneys secrete small amounts of concentrated urine to conserve water and eliminate solutes
    • By diluting urine, kidneys conserve solutes and remove excessive water.

    Urine Transportation, Storage, & Elimination

    • Ureters: transport urine from the renal pelvis of the kidneys to the urinary bladder (approximately 25 to 30 cm long, 3 mm diameter) using peristaltic waves, hydrostatic pressure, and gravity. No anatomical valve prevents backflow.
    • Urinary Bladder: hollow, distensible muscular organ located in the pelvic cavity; storage of urine (700-800ml capacity).
    • Micturition: discharge of urine from the bladder; combination of involuntary and voluntary muscle contractions. When volume increases, stretch receptors send signals to the spinal cord, triggering a micturition reflex, stimulating involuntary detrusor muscle contraction and relaxation of the internal urethral sphincter.
    • Wall of the bladder has a mucosal membrane that folds into rugae, allowing expansion.
    • Trigone: triangular area formed by the openings of two ureters and one urethra
    • Urethra: tube exiting the bladder (male: ~20cm, female: ~3-4cm)
      • Contains internal urethral sphincter (smooth involuntary muscle) and external urethral sphincter (skeletal voluntary muscle).

    Clinical Application: Urethra

    • Urinary tract infections (UTIs) are common in women due to the short length and proximity of the urethra to the anal opening, allowing easier access for intestinal bacteria
    • Urethritis: UTI of the urethra. Cystitis: UTI of the urinary bladder

    Micturition Reflex

    • Accumulation of urine in the bladder triggers stretch receptors in the bladder wall
    • This activates sensory impulses that are transmitted to the spinal cord
    • Spinal reflex initiates involuntary contraction of the detrusor muscle & relaxation of the internal urethral sphincter
    • Urine enters the urethra, and micturition occurs.
    • When bladder control is established, sensory impulses from the bladder are transmitted upward to the brain.
    • Consciousness of passing urine, as bladder fills (300–400ml), can contract the external sphincter (voluntary) & muscle of the pelvic floor, inhibiting micturition (in adult)
    • Overdistention bladder causes involuntary relaxation to occur.

    Composition of Urine

    • Urine is clear and amber due to urobilinogen (bile pigment altered in the intestines)
    • Characteristics:
      • Volume: 1-2 liters per 24-hours (average 1500 ml/day)
      • pH: 4.6–8.0 (average 6)
      • Specific Gravity: 1.001-1.035
      • Color: Yellow due to urochrome
      • Composition: 95% water, 5% solutes (primarily urea).

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    Test your knowledge on the urinary system with this quiz. Questions cover kidney functions, anatomy, and related physiological processes. Perfect for students studying biology or health sciences.

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