Urinary System Histology
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Questions and Answers

What type of epithelium lines the parietal layer of Bowman's capsule in the nephron?

  • Simple squamous epithelium (correct)
  • Simple cuboidal epithelium with brush border
  • Stratified squamous epithelium
  • Ciliated columnar epithelium

Which part of the nephron is primarily involved in the reabsorption of water and solutes?

  • Distal convoluted tubule
  • Ascending loop of Henle
  • Collecting duct
  • Proximal tubule (correct)

What is the composition of the glomerular filtration membrane?

  • Endothelium, thick basement membrane, and mesangial cells
  • Endothelium, thick basement membrane, and podocytes (correct)
  • Simple squamous epithelium, thin basement membrane, and interstitial cells
  • Fenestrated capillaries, microvilli, and podocytes

Which section of the nephron is characterized by simple cuboidal epithelium without a brush border?

<p>Loop of Henle (thin part) (D)</p> Signup and view all the answers

What is the function of podocytes in the nephron?

<p>Facilitating filtration in the glomerulus (C)</p> Signup and view all the answers

What type of epithelium covers the last part of the descending tubule and the first part of the ascending tubule?

<p>Simple cuboidal epithelium (D)</p> Signup and view all the answers

Which component of the nephron is responsible for the formation of concentrated urine?

<p>Collecting duct (B)</p> Signup and view all the answers

Which structure aids in the filtration of blood within the glomerulus?

<p>Podocytes (A)</p> Signup and view all the answers

What is the primary function of the nephron?

<p>Perform osmoregulation and excretion (D)</p> Signup and view all the answers

Which part of the nephron is primarily responsible for filtration?

<p>Renal corpuscle (B)</p> Signup and view all the answers

What is glomerular ultrafiltrate primarily composed of?

<p>Water and low molecular weight substances (A)</p> Signup and view all the answers

Which structure supplies blood to the glomerulus?

<p>Afferent arteriole (C)</p> Signup and view all the answers

What does the distal convoluted tubule mainly regulate?

<p>Ion balance and reabsorption (A)</p> Signup and view all the answers

What is the approximate daily urine production by the nephron?

<p>1.5-2 L (A)</p> Signup and view all the answers

Which part of the nephron is involved in the reabsorption of water and solutes?

<p>Proximal convoluted tubule (C)</p> Signup and view all the answers

How does the nephron contribute to acid-base balance?

<p>By selective reabsorption and secretion (A)</p> Signup and view all the answers

Which layer of the Bowman’s capsule is made up of flattened cells?

<p>Parietal layer (B)</p> Signup and view all the answers

What happens to the blood after it passes through the efferent arteriole of the glomerulus?

<p>It drains out of the glomerulus. (A)</p> Signup and view all the answers

What is the primary function of the macula densa within the juxtaglomerular apparatus?

<p>Monitoring salt concentration in the distal convoluted tubule (A)</p> Signup and view all the answers

What is the primary function of the juxtaglomerular apparatus (JGA)?

<p>Regulation of systemic blood pressure via the renin-angiotensin-aldosterone system (C)</p> Signup and view all the answers

Which cells in the juxtaglomerular apparatus are responsible for secreting renin?

<p>Juxtaglomerular cells (C)</p> Signup and view all the answers

Which cells in the distal convoluted tubule act as chemoreceptors detecting sodium concentration?

<p>Macula densa cells (D)</p> Signup and view all the answers

What forms the filtration slits in the renal corpuscle?

<p>Interdigitating pedicels of podocytes (A)</p> Signup and view all the answers

What structural characteristic distinguishes macula densa cells in the distal convoluted tubule?

<p>They have closely packed nuclei, appearing denser. (A)</p> Signup and view all the answers

Where does the juxtaglomerular apparatus specifically reside?

<p>At the point where the DCT contacts the afferent arteriole (D)</p> Signup and view all the answers

Which of the following best describes podocytes?

<p>Cells that wrap around capillaries and have interdigitating processes (C)</p> Signup and view all the answers

Which of the following best describes the relationship between blood pressure and renin secretion?

<p>Decreased blood pressure stimulates renin secretion. (B)</p> Signup and view all the answers

What role do mesanglial cells play in the kidney?

<p>They support capillary structures and regulate blood flow (A)</p> Signup and view all the answers

What cells are primarily involved in providing structural support in the juxtaglomerular apparatus?

<p>Lacis/granular cells (A)</p> Signup and view all the answers

Which structure acts as a semipermeable barrier in the filtration process of the nephron?

<p>Filtration slits (B)</p> Signup and view all the answers

What type of cells are the Juxtaglomerular cells considered to be?

<p>Modified smooth muscle cells (A)</p> Signup and view all the answers

Which statement accurately reflects the relationship between pedicels and podocytes?

<p>Pedicels interdigitate but do not touch the podocyte cell body (A)</p> Signup and view all the answers

What is a primary characteristic of the filtration slits in the nephron?

<p>They selectively filter based on molecular size and charge (D)</p> Signup and view all the answers

What is the primary function of Bowman's capsule in the nephron?

<p>Filter blood to form glomerular filtrate (C)</p> Signup and view all the answers

Which cells make up the visceral layer of Bowman's capsule?

<p>Podocytes (B)</p> Signup and view all the answers

Where is the renal tubule's urinary pole located in Bowman's capsule?

<p>Opposite to the vascular pole (D)</p> Signup and view all the answers

What is the primary component of glomerular filtrate?

<p>Water, salts, glucose, and proteins (D)</p> Signup and view all the answers

What type of epithelium forms the parietal layer of Bowman's capsule?

<p>Simple squamous epithelium (A)</p> Signup and view all the answers

What anatomical feature is found between the visceral and parietal layers of Bowman's capsule?

<p>Bowman's space (D)</p> Signup and view all the answers

Which vessel brings blood into the glomerulus?

<p>Afferent arteriole (D)</p> Signup and view all the answers

What is the function of the capillary loops in the glomerulus?

<p>Facilitate filtration of blood (C)</p> Signup and view all the answers

What distinguishes the vascular pole of the renal corpuscle?

<p>Entrance and exit of blood vessels (B)</p> Signup and view all the answers

How does glomerular filtration contribute to osmotic regulation?

<p>It balances water and electrolytes in blood (C)</p> Signup and view all the answers

What is the primary function of the epididymis in the male reproductive system?

<p>Storage and maturation of sperm (D)</p> Signup and view all the answers

Which role is NOT attributed to the accessory glands in the male reproductive system?

<p>Regulating temperature for sperm production (C)</p> Signup and view all the answers

What type of tissue primarily constitutes the wall of the ductus deferens?

<p>Smooth muscle and connective tissue (C)</p> Signup and view all the answers

During the sperm maturation process, which stage follows the formation of spermatids?

<p>Spermatozoa (D)</p> Signup and view all the answers

What is a primary function of the prostate gland?

<p>Adding enzymes to seminal fluid (A)</p> Signup and view all the answers

What is the primary function of the epididymis?

<p>To store and mature sperm (C)</p> Signup and view all the answers

Which accessory gland is responsible for secreting alkaline lubrication?

<p>Bulbourethral gland (B)</p> Signup and view all the answers

What role does the ductus deferens play in the male reproductive system?

<p>Transport of sperm to the ejaculatory duct (A)</p> Signup and view all the answers

How does sperm maturation primarily occur?

<p>In the epididymis through physical and chemical changes (C)</p> Signup and view all the answers

Which statement accurately describes the prostate gland?

<p>It contributes nutrients to the seminal fluid. (D)</p> Signup and view all the answers

What is a key structural feature of the ductus deferens?

<p>Smooth muscle for peristaltic movement (C)</p> Signup and view all the answers

Which function is NOT associated with the seminal vesicles?

<p>Storage of sperm (C)</p> Signup and view all the answers

Which of the following accurately describes the primary secretion of the prostate gland?

<p>It mainly secretes alkaline fluid. (A)</p> Signup and view all the answers

What is the main purpose of the seminal fluid in ejaculation?

<p>To assist in the movement of sperm (B)</p> Signup and view all the answers

What is the anatomical location of the bulbourethral glands?

<p>Adjacent to the prostate gland (C)</p> Signup and view all the answers

What is the primary function of the smooth muscle in the ductus deferens?

<p>Engage in intense rhythmic contraction during ejaculation (B)</p> Signup and view all the answers

Which epithelial type lines the ductus deferens and helps propel spermatozoa?

<p>Pseudostratified columnar epithelium (B)</p> Signup and view all the answers

What is one of the main components of the seminal fluid produced by the prostate gland?

<p>Citrate (A)</p> Signup and view all the answers

Which accessory gland contributes the largest percentage of seminal fluid?

<p>Prostate gland (D)</p> Signup and view all the answers

What layer in the ductus deferens is responsible for its ability to expand during ejaculation?

<p>Lamina propria (D)</p> Signup and view all the answers

What is the function of stereocilia found in the ductus deferens?

<p>Propel sperm and resorb fluid (B)</p> Signup and view all the answers

Which layer of smooth muscle in the ductus deferens is primarily responsible for strong contractions?

<p>Combined smooth muscle layers (B)</p> Signup and view all the answers

What is a unique characteristic of the prostate gland regarding its location?

<p>It surrounds the neck of the bladder. (A)</p> Signup and view all the answers

What role do prostaglandins secreted by the prostate gland play?

<p>Aid in uterine contractions (B)</p> Signup and view all the answers

Which cell type within the epididymis is primarily responsible for the storage and maturation of spermatozoa?

<p>Columnar epithelial cells (D)</p> Signup and view all the answers

Which histological feature distinguishes the ductus deferens from other reproductive structures?

<p>Three layers of smooth muscle coat (B)</p> Signup and view all the answers

In which anatomical zone of the prostate gland does the prostate’s bulk predominantly reside?

<p>Peripheral zone (C)</p> Signup and view all the answers

What role do paraurethral glands serve within the male reproductive system?

<p>Secretion of lubricating mucus (B)</p> Signup and view all the answers

What type of tissue is primarily found in the corpus spongiosum of the penis?

<p>Erectile tissue with vascular sinuses (C)</p> Signup and view all the answers

Which component of the testis is primarily responsible for androgenic hormone synthesis?

<p>Leydig cells (C)</p> Signup and view all the answers

Which anatomical feature surrounds the prostatic urethra in the prostate gland?

<p>Transition zone (B)</p> Signup and view all the answers

What is the primary role of the epididymis in the male reproductive system?

<p>Storage and maturation of sperm (C)</p> Signup and view all the answers

Which accessory gland contributes fluid that nourishes and protects sperm?

<p>Seminal vesicle (C)</p> Signup and view all the answers

Which histological feature is characteristic of the ductus deferens?

<p>Pseudostratified columnar epithelium (A)</p> Signup and view all the answers

During which process do spermatogonia differentiate into sperm?

<p>Spermatogenesis (B)</p> Signup and view all the answers

What is a key function of the prostate gland in male reproduction?

<p>Production of seminal fluid that enhances sperm motility (C)</p> Signup and view all the answers

Which structure is responsible for transporting sperm from the epididymis to the ejaculatory duct?

<p>Ductus deferens (B)</p> Signup and view all the answers

Which hormone is primarily produced by Leydig cells in the testes?

<p>Testosterone (D)</p> Signup and view all the answers

What histological feature is unique to the prostate gland?

<p>Complex tubular structures (A)</p> Signup and view all the answers

Which phase of spermatogenesis directly involves meiosis?

<p>Development of secondary spermatocytes (B)</p> Signup and view all the answers

What is a primary function of Sertoli cells in the testes?

<p>Support and nourishment of developing sperm (A)</p> Signup and view all the answers

What is a significant function of cervical mucus during ovulation?

<p>It provides a medium for sperm migration. (A)</p> Signup and view all the answers

During which phase of the menstrual cycle does the corpus luteum primarily function?

<p>Early secretory phase (A)</p> Signup and view all the answers

Which hormonal change triggers the development of the ovarian follicle during the menstrual cycle?

<p>Rise in follicle-stimulating hormone (FSH) (A)</p> Signup and view all the answers

What effect does fertilization have on the menstrual cycle?

<p>It leads to the maintenance of the corpus luteum. (C)</p> Signup and view all the answers

Which phase immediately follows the ovulatory phase in the menstrual cycle?

<p>Luteal phase (A)</p> Signup and view all the answers

What is the primary hormone produced by the corpus luteum during early pregnancy?

<p>Progesterone (B)</p> Signup and view all the answers

What initiates the maintenance of the corpus luteum after fertilization?

<p>Human chorionic gonadotropin (hCG) (A)</p> Signup and view all the answers

During which phase of the menstrual cycle does the corpus luteum form?

<p>Luteal phase (C)</p> Signup and view all the answers

Which cells are responsible for hormone production in the corpus luteum?

<p>Granulosa lutein cells (D)</p> Signup and view all the answers

What is the primary function of hCG in early pregnancy?

<p>Maintaining corpus luteum function (C)</p> Signup and view all the answers

What occurs to the corpus luteum if fertilization does not take place?

<p>It transforms into a corpus albicans (B)</p> Signup and view all the answers

Which phase of the menstrual cycle is crucial for the development of the oocyte?

<p>Follicular phase (A)</p> Signup and view all the answers

What typically happens to the corpus luteum during early pregnancy?

<p>It is maintained and enlarged (C)</p> Signup and view all the answers

What triggers the secretion of LH that leads to ovulation?

<p>Peak levels of oestrogen (B)</p> Signup and view all the answers

Which phase of the menstrual cycle occurs after ovulation?

<p>Luteal phase (A)</p> Signup and view all the answers

What is the primary role of the corpus luteum during the luteal phase?

<p>To secrete oestrogen and progesterone (C)</p> Signup and view all the answers

What is the average duration of the menstrual phase?

<p>3-5 days (B)</p> Signup and view all the answers

Which process does oestrogen primarily influence to facilitate the movement of the egg in the fallopian tube?

<p>Movement of cilia (D)</p> Signup and view all the answers

What occurs if fertilization does not take place after ovulation?

<p>Menstruation occurs (D)</p> Signup and view all the answers

Which type of follicles are primarily present in the ovaries during the follicular phase?

<p>Primordial and primary follicles (D)</p> Signup and view all the answers

Which hormone surge is responsible for the rupture of the follicle during ovulation?

<p>LH (B)</p> Signup and view all the answers

What is the role of peg cells in the fallopian tube?

<p>Secreting nutrient-rich fluid (C)</p> Signup and view all the answers

At which part of the fallopian tube does fertilization typically occur?

<p>Ampulla (C)</p> Signup and view all the answers

What is the main role of LH in ovarian follicle development?

<p>Triggers the release of the oocyte during ovulation (C)</p> Signup and view all the answers

Which follicular stage is characterized by a secondary oocyte being surrounded by a zona pellucida?

<p>Mature follicles (B)</p> Signup and view all the answers

What distinguishes mature follicles from primary follicles?

<p>Significant hormonal activity and larger antrum (B)</p> Signup and view all the answers

What occurs to the oocyte just before ovulation?

<p>It resumes meiosis and progresses to metaphase II (A)</p> Signup and view all the answers

Which hormone primarily stimulates the production of estrogen in mature follicles?

<p>FSH (B)</p> Signup and view all the answers

What is the function of the cumulus oophorus in the mature follicle?

<p>Facilitates communication between follicular cells and oocyte (B)</p> Signup and view all the answers

Which of the following describes the antrum in a mature follicle?

<p>Prominent and filled with follicular fluid (C)</p> Signup and view all the answers

What is the primary phase during which oocytes are arrested in metaphase II?

<p>Prior to fertilization (D)</p> Signup and view all the answers

Which structure forms the protective layer around the ovum during the mature follicle stage?

<p>Zona pellucida (C)</p> Signup and view all the answers

What is the primary purpose of the hormonal changes in the menstrual cycle before ovulation?

<p>To enhance follicular development and oocyte maturation (C)</p> Signup and view all the answers

What is the primary hormone secreted by lutein cells in the corpus luteum?

<p>Progesterone (C)</p> Signup and view all the answers

What happens to the corpus luteum if fertilization does not occur?

<p>It degenerates into corpus albicans. (B)</p> Signup and view all the answers

How long does the corpus luteum typically function if pregnancy does not occur?

<p>About 10 to 14 days (A)</p> Signup and view all the answers

Which of the following statements is true regarding the late corpus luteum during pregnancy?

<p>It remains active for about 10 to 12 weeks. (B)</p> Signup and view all the answers

What structural change occurs to the corpus luteum after ovulation if fertilization does not take place?

<p>It is replaced by fibrous connective tissue. (D)</p> Signup and view all the answers

What is the role of the corpus luteum in the menstrual cycle?

<p>It supports the early stages of pregnancy. (A)</p> Signup and view all the answers

What distinguishes the corpus albicans from the corpus luteum?

<p>Corpus albicans has no cellular activity. (D)</p> Signup and view all the answers

What initiates the breakdown of the uterine lining if pregnancy does not occur?

<p>Withdrawal of ovarian hormones. (C)</p> Signup and view all the answers

What indicates the conclusion of the ovulatory phase?

<p>The presence of corpus albicans. (D)</p> Signup and view all the answers

Which statement accurately reflects the features of the early corpus luteum?

<p>It typically functions for about 10 to 14 days. (A)</p> Signup and view all the answers

Flashcards

Bowman's capsule lining

The outer lining of Bowman's capsule is simple squamous epithelium, while the inner layer (visceral) consists of podocytes

Proximal tubule lining

The lining of the proximal tubule is simple cuboidal epithelium with a brush border.

Loop of Henle (thin part) lining

The thin part of the loop of Henle is lined with simple squamous epithelium.

Distal convoluted tubule lining

The distal convoluted tubule is lined with simple cuboidal epithelium, and it lacks a brush border.

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Collecting duct lining

The collecting duct lining is also simple cuboidal epithelium without a brush border.

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Glomerular filtration membrane: Endothelium

The fenestrated (porous) capillaries composing the glomerulus.

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Glomerular filtration membrane: Basement membrane

A thick membrane formed by both endothelial and podocyte cells.

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Glomerular filtration membrane: Podocytes

Specialized cells forming the inner layer of the Bowman's capsule.

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Nephron size

Each nephron is approximately 50-55 micrometers in size.

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Nephron parts

A nephron has five main parts: renal corpuscle, proximal convoluted tubule, loop of Henle, distal convoluted tubule, and collecting ducts.

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Renal corpuscle

The first part of a nephron, which is composed of glomerulus and Bowman's capsule. It filters blood plasma.

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Glomerulus

A network of capillaries within the renal corpuscle that filters blood.

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Bowman's capsule

A cup-shaped structure that surrounds the glomerulus, collecting the filtered fluid.

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Glomerular Filtration

The process where water and low-molecular weight substances in the blood are filtered into Bowman's space.

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Nephron function

Osmoregulation and excretion. It produces urine by filtration, reabsorption, secretion, and maintaining acid-base balance.

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Glomerular ultrafiltrate

The filtered material from the blood that enters Bowman's capsule.

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Afferent arteriole

The blood vessel that delivers blood to the glomerulus.

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Efferent arteriole

The blood vessel leaving the glomerulus.

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Podocyte Foot Processes

Finger-like projections of podocytes that interdigitate with each other, forming filtration slits.

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Filtration Slits

Spaces between interdigitating podocyte foot processes, forming a semipermeable barrier for filtration.

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What does the juxtaglomerular apparatus (JGA) consist of?

The JGA is formed by the macula densa, mesangial cells, and juxtaglomerular cells.

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Macula Densa

Specialized epithelial cells in the distal convoluted tubule (DCT) where it contacts the afferent arteriole.

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Juxtaglomerular Cells (JG cells)

Modified smooth muscle cells of the afferent arteriole containing renin granules.

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Function of the Macula Densa

Monitors salt concentration in the tubule, helping maintain normal blood pressure.

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Function of Juxtaglomerular Cells

Contain renin granules which release renin to raise blood pressure.

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Where is the JGA located?

The JGA is located in the nephron where the distal convoluted tubule turns back and contacts the afferent arteriole.

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Why is the JGA important?

The JGA plays a key role in regulating blood pressure and filtering blood.

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What is the relationship between the JGA and blood pressure?

The JGA helps regulate blood pressure by controlling renin release, which affects blood volume and pressure.

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What does the Bowman's Capsule encapsulate?

The Bowman's Capsule completely surrounds the glomerulus, except at the vascular pole, and is composed of two layers: parietal and visceral.

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What makes up the glomerulus?

The glomerulus is a network of capillaries that form a ball-like structure within the Bowman's capsule, branching off from the afferent arteriole and joining the efferent arteriole.

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What is the difference between the parietal and visceral layers of Bowman's capsule?

The parietal layer is the outer layer and is made up of simple squamous epithelium, while the visceral layer is the inner layer and is comprised of specialized cells called podocytes.

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What is the significance of Bowman's Space?

Bowman's Space is the space between the parietal and visceral layers of Bowman's capsule, where the glomerular filtrate (filtered blood) collects before entering the renal tubule.

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What is the glomerular filtrate composed of?

The glomerular filtrate contains water, salts (NaCl), glucose, protein molecules, and other small molecules filtered from the blood.

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What is the function of podocytes?

Podocytes are specialized cells that form the visceral layer of Bowman's capsule, creating filtration slits that control the movement of substances from the blood into Bowman's Space.

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What is the vascular pole?

The vascular pole is the region where the afferent and efferent arterioles connect to the glomerulus.

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What is the urinary pole?

The urinary pole is the region where the filtered fluid from Bowman's Space enters the renal tubule.

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What is the difference between an afferent and efferent arteriole?

The afferent arteriole brings blood to the glomerulus, while the efferent arteriole carries blood away from the glomerulus.

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How does the renal corpuscle contribute to urine formation?

The renal corpuscle filters blood plasma, creating glomerular filtrate, which is the first step in urine formation. It's like the initial 'sieve' of the urinary system.

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JGA

The juxtaglomerular apparatus (JGA) is a specialized structure in the nephron where the distal convoluted tubule (DCT) comes into contact with the afferent arteriole. It consists of three cell types: macula densa, juxtaglomerular cells, and extraglomerular mesangial cells.

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What is the function of the JGA?

The JGA plays a vital role in regulating systemic blood pressure through the renin-angiotensin-aldosterone system (RAAS). It acts as both a baroreceptor (detecting blood pressure) and chemoreceptor (detecting sodium concentration) to control blood pressure by secreting renin.

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Juxtaglomerular Cells

These cells are modified smooth muscle cells found in the wall of the afferent arteriole, which is the blood vessel supplying the glomerulus. They contain granules of renin, a hormone that helps raise blood pressure.

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Extraglomerular Mesangial Cells

These cells are located in the triangular space between the afferent and efferent arterioles, and the macula densa. Their exact function is not fully understood, but they may play a role in regulating blood flow through the glomerulus.

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Prostate Gland Zones

The prostate gland is divided into four zones: the transition zone, central zone, peripheral zone, and the anterior fibromuscular stroma. Each zone has distinct functions and anatomical features.

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Transition Zone

This zone surrounds the proximal part of the prostatic urethra and is the site of benign prostatic hyperplasia (BPH).

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Central Zone

The central zone is located posterior to the transition zone and encircles the ejaculatory ducts.

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Peripheral Zone

This zone makes up the majority of the prostatic gland and is the most common location for prostate cancer.

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Anterior Fibromuscular Stroma

This zone is located in the anterior part of the prostate and is a non-glandular, dense connective tissue.

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Prostate Gland Capsule

The prostate gland is surrounded by a capsule of dense connective tissue and smooth muscle cells.

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What is the role of the Prostate Gland?

The prostate gland plays a vital role in male reproductive health by producing a fluid that contributes to semen. It helps protect and nourish sperm during ejaculation.

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Erectile Tissue

Erectile tissue is a specialized vascular tissue found in the penis, composed of spongy fibrous tissue containing anastomosing vascular sinuses. It fills with blood during arousal, causing erection.

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Ductus deferens epithelium

The epithelium lining the ductus deferens is pseudostratified columnar with long stereocilia. The stereocilia aid in propelling sperm and reabsorbing fluid.

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Ductus deferens lamina propria

The lamina propria in ductus deferens is a layer of connective tissue that forms longitudinal folds. These folds allow for expansion during ejaculation.

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Ductus deferens smooth muscle

The ductus deferens has three layers of smooth muscle: inner and outer longitudinal layers, and an intermediate circular layer. These layers contract to propel sperm forcefully.

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Seminal vesicle contribution

Seminal vesicles contribute around 30% of the seminal fluid. Their alkaline fluid neutralizes acidic secretions of the female reproductive tract, promoting sperm viability.

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Prostate gland function

The prostate gland contributes 60% of seminal fluid, rich in citrate for sperm energy. It also produces enzymes to break down the semen clot after ejaculation.

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Bulbourethral gland function

Bulbourethral glands provide 10% of seminal fluid, mostly lubricating mucus. This mucus helps sperm travel smoothly through the urethra and female reproductive tract.

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Prostate gland location

The prostate gland is located around the neck of the bladder and surrounds the prostate urethra. It merges with the ejaculatory ducts.

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Prostate gland secretions

The prostate gland secretes citrate, an energy source for sperm, and contains prostaglandins that stimulate uterine contractions, assisting sperm transport.

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Role of stereocilia in testis

Stereocilia in the testis are involved in absorbing excess fluid, maintaining the appropriate environment for sperm development.

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Smooth muscle distribution in ductus deferens

Smooth muscle layers in the ductus deferens increase in complexity from the proximal to the distal aspect. Proximal: single circular layer for slow rhythmic movement. Distal: longitudinal and circular layers for intense rhythmic contractions during ejaculation.

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Seminiferous Tubules

Coiled tubes in the testes where sperm cells are produced.

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Epididymis

A coiled tube attached to the testis where sperm mature and are stored.

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Ductus (Vas) Deferens

A muscular tube carrying sperm from the epididymis to the ejaculatory duct.

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Ejaculatory Duct

Short tubes that merge with the urethra, allowing sperm to exit the body during ejaculation.

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Penile Urethra

The final segment of the urethra that passes through the penis, carrying urine and semen.

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Seminal Vesicles

Sac-like glands that secrete a fluid rich in fructose, providing energy for sperm.

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Prostate Gland

A gland that surrounds the urethra and secretes a milky fluid that makes up part of semen.

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Bulbourethral Glands (Cowper's glands)

Two small glands that secrete a clear, alkaline fluid that lubricates the urethra and neutralizes acidity.

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Penis

The male external genitalia, which serves as the organ of copulation.

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Semen

The thick, milky fluid ejaculated during orgasm, containing sperm and other fluids.

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Male Reproductive System

The male reproductive system is responsible for producing sperm and delivering it to the female reproductive system. It consists of the testes, duct system, accessory glands, and external genitalia.

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Duct System

The duct system carries sperm from the testes to the outside of the body. This system includes the epididymis, vas deferens, ejaculatory ducts, and urethra.

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Spermatogenesis

Spermatogenesis is the process of sperm cell production. It involves meiosis and cellular differentiation.

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Meiosis in Spermatogenesis

During spermatogenesis, meiosis is the process of chromosome reduction, resulting in haploid sperm cells with half the number of chromosomes compared to other body cells.

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Spermiogenesis

Spermiogenesis is the final stage of spermatogenesis, where sperm cells undergo differentiation to develop their mature structure, including a head, midpiece, and tail.

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Sertoli Cells

Sertoli cells provide support and nourishment for developing sperm cells within the seminiferous tubules.

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Leydig Cells

Leydig cells produce testosterone, the male sex hormone, which is crucial for sperm production and development of male secondary sex characteristics.

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Pathway of Sperm

Sperm travels from the testes through the epididymis, vas deferens, ejaculatory ducts, and urethra, eventually being released outside of the body.

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Sperm Pathway

The journey of sperm from production in the seminiferous tubules to ejaculation. It involves several structures: seminiferous tubules, rete testis, ductuli efferentes, epididymis, vas deferens, ejaculatory ducts, prostate, seminal vesicles, and urethra.

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Testis Capsule

A dense fibrous capsule surrounding the testis. It is called the tunica albuginea and is made of connective tissue, providing support and contributing to the formation of septa that divide the testis into lobules.

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Tunica Vaginalis

A double-layered mesothelial membrane covering the testis. It provides lubrication and allows for testis movement within the scrotum.

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Tunica Vascularis

A layer of loose connective tissue beneath the tunica albuginea. It contains blood and lymphatic vessels, supplying nutrients and removing waste from the testis.

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Seminiferous Tubules Lining

The inner lining of seminiferous tubules is composed of two main cell types: Sertoli cells and germ cells. These cells work together to produce sperm cells.

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Corpus luteum of pregnancy

The corpus luteum, a temporary endocrine structure in the ovary, is greatly enlarged during pregnancy. It produces progesterone, essential for maintaining the uterine lining and supporting early pregnancy until the placenta takes over.

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Human chorionic gonadotropin (hCG)

A hormone produced by the developing embryo shortly after implantation. hCG signals the corpus luteum to continue functioning and producing progesterone.

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Follicular phase

The first phase of the menstrual cycle, characterized by the development of a dominant follicle in the ovary and the preparation of the uterine lining for a possible pregnancy.

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Luteal phase

The second phase of the menstrual cycle, following ovulation. During this phase, the corpus luteum forms and produces progesterone to maintain the uterine lining.

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Ovulation

The release of a mature egg from the ovary, marking the transition from the follicular phase to the luteal phase.

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Granulosa lutein cells

Cells formed by the remaining granulosa cells of the follicle after ovulation. These cells enlarge and calcify as pregnancy progresses.

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Placenta

A temporary organ that forms in the uterus during pregnancy. The placenta supports the developing embryo and fetus by providing nutrients and oxygen and removing waste products.

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Progesterone

A hormone produced by the corpus luteum and later by the placenta. Progesterone is crucial for maintaining the uterine lining and supporting early pregnancy.

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Corpus Luteum

A temporary endocrine gland formed after ovulation from the ruptured follicle, producing progesterone and estrogen.

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FSH and LH

Hormones that control the ovarian cycle. FSH stimulates follicle growth, while LH triggers ovulation.

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Oviduct (Fallopian Tube)

A tube that connects the ovary to the uterus, where fertilization occurs.

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Cilia in Oviduct

Hair-like structures lining the oviduct that beat rhythmically to propel the egg towards the uterus.

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Peg Cells

Specialized cells in the oviduct that secrete a nutrient-rich fluid to support the egg as it travels.

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Uterine Lining (Endometrium)

The inner lining of the uterus, which thickens in preparation for pregnancy and sheds during menstruation.

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Menstruation

The shedding of the uterine lining, occurring when an egg is not fertilized, resulting in a monthly bleed.

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Mature Follicle

A fully developed follicle, ready for ovulation, with a large antrum, multilayered granulosa cells, and a secondary oocyte arrested in metaphase II.

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Follicular Antrum

A fluid-filled cavity within a developing follicle, expanding as the follicle matures.

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Cumulus Oophorus

A cluster of granulosa cells surrounding the oocyte within a mature follicle.

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Corona Radiata

A layer of granulosa cells closely associated with the oocyte, aiding in its release during ovulation.

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Zona Pellucida

A protective layer surrounding the oocyte, essential for fertilization.

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Oestrogen Production in Mature Follicles

Mature follicles produce high levels of oestrogen due to the increased number of granulosa cells.

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FSH & LH Influence

Mature follicles are influenced by both FSH and LH, especially in the lead-up to ovulation.

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Meiosis I

The process of chromosome reduction in a primary oocyte, forming a secondary oocyte with half the number of chromosomes.

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Meiosis II Completion

The secondary oocyte completes meiosis II only after fertilization.

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Ovum

The mature egg cell produced after ovulation.

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Cervix

The lower, narrow part of the uterus extending into the vagina. It forms a physical barrier between the vagina and uterus, acting as a passageway for sperm and a protective barrier during pregnancy.

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Cervical Mucus

A thick, sticky substance secreted by cells lining the endocervical canal of the cervix. It acts as a barrier to microbes and helps guide sperm towards the uterus.

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Vagina

A muscular canal connecting the cervix to the outside of the body. It acts as the birth canal for the baby and receives the penis during intercourse.

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Glycogen Levels in Vagina

The epithelial lining of the vagina contains glycogen granules, which change in levels throughout the menstrual cycle. These glycogen levels influence the vaginal environment and the growth of beneficial bacteria.

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Vaginal Lactic Acid

Lactic acid is produced in the vagina by bacteria fermenting glycogen. This acidic environment helps maintain a healthy vaginal microbiome and prevent infection.

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Lutein Cells

Enlarged granulosa and theca cells within the corpus luteum, responsible for secreting progesterone and estrogen.

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Corpus Luteum of Menstruation

A corpus luteum that degenerates if fertilization does not occur. This degeneration triggers menstruation.

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Corpus Albicans

A small, white, fibrous scar tissue that forms after the corpus luteum degenerates. It signifies the end of the ovulatory phase.

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What are the functions of the corpus luteum?

The corpus luteum plays a crucial role in the menstrual cycle and early pregnancy. It produces progesterone and estrogen to support the uterine lining, preparing it for a potential pregnancy. If fertilization occurs, it continues to function until the placenta takes over. If no fertilization happens, it degenerates, leading to menstruation.

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What happens to the corpus luteum if fertilization doesn't occur?

If fertilization does not occur, the corpus luteum degenerates, leading to a decrease in progesterone and estrogen levels. This hormone withdrawal causes the breakdown of the uterine lining, resulting in menstruation.

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How does the corpus luteum support early pregnancy?

The corpus luteum produces high levels of progesterone, crucial for maintaining the uterine lining and supporting the development of the early embryo until the placenta takes over this function.

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What is hCG and what does it do?

Human Chorionic Gonadotropin (hCG) is a hormone produced by the developing embryo shortly after implantation. It signals to the corpus luteum to continue producing progesterone, thereby sustaining the pregnancy.

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What is the difference between the luteal phase and the follicular phase?

The follicular phase is the first part of the menstrual cycle, during which a dominant follicle develops in the ovary, preparing the uterine lining for a possible pregnancy. The luteal phase follows ovulation and is characterized by the formation of the corpus luteum, which produces progesterone to maintain the uterine lining.

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What are the functions of progesterone in the female reproductive system?

Progesterone plays a vital role in the female reproductive system. It helps prepare the uterine lining for a possible pregnancy, maintains the lining once an egg is fertilized, and suppresses ovulation during pregnancy. It also contributes to breast development and milk production.

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Study Notes

Urinary System Overview

  • The urinary system is responsible for filtering waste from the blood and producing urine.
  • It consists of kidneys, ureters, bladder, and urethra.

Kidney Structure and Function

  • Kidneys filter blood to produce urine.
  • The basic microscopic structure includes cortex, medulla, pyramid, calyx, pelvis and proximal ureter.
  • The nephron is the functional unit of the kidney, and it has five parts: renal corpuscle, Bowman's capsule, proximal convoluted tubule, loop of Henle, and collecting ducts.

Renal Corpuscle

  • It's where filtration of blood begins to create glomerular filtrate.
  • This structure contains a glomerulus, a capillary network, and Bowman's capsule.
  • The filtration membrane consists of endothelium, basement membrane, and podocytes. Filtering occurs across this membrane.

Proximal Convoluted Tubule (PCT)

  • Located in the cortex, near Bowman's capsule.
  • Reabsorbs substances like sodium, glucose, and amino acids from the filtrate.

Loop of Henle

  • U-shaped structure located in the medulla.
  • Important for concentrating urine by creating a concentration gradient.

Distal Convoluted Tubule (DCT)

  • Located in the cortex, near the collecting ducts.
  • Reabsorbs substances selectively based on body needs and hormonal controls.

Collecting Ducts

  • Collects urine from several nephrons.
  • Reabsorbs water and ions, further concentrating urine.

Kidney Lobules

  • Consist of a collecting duct and all nephrons, along with the overlying medullary pyramid and cortex.

Renal Papillae

  • Urine drains from collecting ducts into the renal papillae.

Glomerular Filtration Membrane

  • Three layers: endothelium of glomerular capillaries, basement membrane, and podocytes of Bowman's capsule
  • It filters the blood, allowing small molecules (water, salts, glucose) but not large molecules (proteins, cells) to pass into the Bowman's capsule.

Podocytes

  • Cells of the visceral layer of Bowman's capsule.
  • Possess foot processes that create filtration slits.
  • Their foot processes wrap around the glomerular capillaries, creating a filtration barrier.

Juxtaglomerular Apparatus (JGA)

  • A region where the afferent arteriole comes into contact with the distal convoluted tubule (DCT).
  • Contains specialized cells (macula densa and juxtaglomerular cells) that regulate blood pressure.

Renal Vasculature

  • Blood vessels supply blood to the glomerulus and nephrons.
  • The afferent arteriole brings blood into the glomerulus, and the efferent arteriole carries filtered blood away.
  • The peritubular capillaries surround the tubules.
  • Vasa recta are specialized capillaries in the medulla.

Lower Urinary System

  • Consists of the pelvis, ureters, bladder, and urethra.
  • The ureters transport urine from the kidneys to the bladder.
  • The bladder stores urine.
  • The urethra transports urine out of the body.
  • All of these components have a mucosa, muscular layer, and adventitia except urethra.

Urothelium

  • Specialised epithelial cells in the urinary system, including the bladder, ureters and part of the renal pelvis.
  • The unique characteristic of the urothelium is its ability to stretch and maintain impermeability to urine.

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Description

Test your knowledge on the structure and function of the urinary system and kidneys. This quiz covers the role of the kidneys, the nephron's components, and the process of filtration. Understand the anatomy and physiology behind urine production.

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