Urinary System Overview and Components
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Questions and Answers

What is the primary function of the nephron during urine processing?

  • Reabsorption and double checking for missed waste (correct)
  • Excretion of all waste materials
  • Secretion of nutrients back into the blood
  • Filtration of blood plasma

What percentage of nephrons are cortical nephrons?

  • 15%
  • 85% (correct)
  • 50%
  • 100%

Which structure is responsible for producing a protein-free solution known as glomerular filtrate?

  • Collecting duct
  • Glomerular capsule (correct)
  • Proximal convoluted tubule
  • Renal tubule

What distinguishes juxtamedullary nephrons from cortical nephrons?

<p>Their capsule is located near the border of the cortex and medulla (C)</p> Signup and view all the answers

Which component of the renal corpuscle forms the visceral layer of the glomerular capsule?

<p>Podocytes that wrap around glomerular capillaries (B)</p> Signup and view all the answers

The thin descending limb of the nephron loop primarily allows the passage of which substance?

<p>Water only (B)</p> Signup and view all the answers

What is the main characteristic of cortical nephrons compared to juxtamedullary nephrons?

<p>They have a shorter nephron loop (B)</p> Signup and view all the answers

Which part of the nephron is located in the medulla?

<p>Collecting duct (B)</p> Signup and view all the answers

Which structure in the renal corpuscle is primarily responsible for filtration?

<p>Capillary endothelium (B)</p> Signup and view all the answers

What is the primary function of the basal lamina in the renal corpuscle?

<p>Restricts passage of large proteins (D)</p> Signup and view all the answers

Which type of cells can be found in the visceral epithelium of the glomerular capsule?

<p>Podocytes (A)</p> Signup and view all the answers

What occurs at the vascular pole of the renal corpuscle?

<p>Blood enters through the afferent arteriole (A)</p> Signup and view all the answers

What role does blood pressure play in the renal corpuscle?

<p>Drives the filtration of fluid and solutes (B)</p> Signup and view all the answers

Which artery does not contribute to the vascular supply of the renal cortex?

<p>Pulmonary artery (C)</p> Signup and view all the answers

What is the primary function of cortical radiate veins within the renal system?

<p>Drain deoxygenated blood from the renal cortex (C)</p> Signup and view all the answers

Which structure is the basic functional unit of the kidney?

<p>Nephron (B)</p> Signup and view all the answers

Which process is NOT a main function of the nephron?

<p>Secretion of hormones (B)</p> Signup and view all the answers

What percentage of water is reabsorbed by the nephron from the filtrate?

<p>80% (A)</p> Signup and view all the answers

Which vein directly drains blood from the renal pyramids?

<p>Arcuate vein (D)</p> Signup and view all the answers

Which of the following does NOT include the term 'cortical radiate'?

<p>Cortical radiate ligaments (A)</p> Signup and view all the answers

What connects the arcuate arteries to the interlobar arteries within the renal system?

<p>Cortical radiate arteries (D)</p> Signup and view all the answers

What is the primary function of podocytes in the glomerular epithelium?

<p>To filter blood (B)</p> Signup and view all the answers

What are filtration slits, and where are they located?

<p>Gaps between the extensions of podocytes (C)</p> Signup and view all the answers

Which of the following substances is typically found in the filtrate derived from the glomerulus?

<p>Glucose (C)</p> Signup and view all the answers

What role do mesangial cells have in the filtration structures?

<p>They provide structural support (D)</p> Signup and view all the answers

Which layer of the filtration membrane blocks the passage of large plasma proteins?

<p>Basal lamina (A)</p> Signup and view all the answers

What is the primary role of juxtaglomerular cells in the renal corpuscle?

<p>They secrete hormones (D)</p> Signup and view all the answers

Which components are present in the capsular space of the renal corpuscle?

<p>Glomerular filtrate (D)</p> Signup and view all the answers

What do secondary processes of podocytes specifically block?

<p>Passage of almost all plasma proteins (D)</p> Signup and view all the answers

Which function of the urinary system helps to maintain blood pressure?

<p>Regulates blood volume (A)</p> Signup and view all the answers

What is the main role of the nephron in the kidneys?

<p>Filters blood (D)</p> Signup and view all the answers

Which kidney is positioned higher than the other due to the liver's presence?

<p>Left kidney (C)</p> Signup and view all the answers

What component of the urinary system temporarily stores urine?

<p>Urinary bladder (B)</p> Signup and view all the answers

What tissue layer directly covers the kidneys?

<p>Fibrous capsule (A)</p> Signup and view all the answers

Which substance is eliminated by the urinary system as a form of waste?

<p>Urea (B)</p> Signup and view all the answers

What role does the urinary system play in stabilizing blood pH?

<p>Regulating ion concentrations (B)</p> Signup and view all the answers

Which of these statements about the blood supply to the kidneys is correct?

<p>The renal artery supplies blood to the kidneys (B)</p> Signup and view all the answers

Which kidney structure is responsible for connecting to the ureter?

<p>Renal pelvis (A)</p> Signup and view all the answers

Which of the following ions is NOT regulated by the urinary system?

<p>Calcium (Ca2+) (B)</p> Signup and view all the answers

What is the function of the urethra in the urinary system?

<p>Conducts urine to the exterior (D)</p> Signup and view all the answers

The structure that collects urine from the renal pyramids is called the:

<p>Minor calyx (A)</p> Signup and view all the answers

Which organ assists the liver in detoxifying poisons as part of the urinary system?

<p>Kidney (D)</p> Signup and view all the answers

The outermost layer of connective tissue surrounding the kidneys is known as:

<p>Renal fascia (B)</p> Signup and view all the answers

What is the primary function of macula densa cells?

<p>To monitor electrolyte concentration (A)</p> Signup and view all the answers

What hormone do juxtaglomerular cells primarily secrete?

<p>Renin (B)</p> Signup and view all the answers

How do macula densa and juxtaglomerular cells respond to low blood pressure or low electrolyte concentrations?

<p>Secrete renin (B)</p> Signup and view all the answers

Which of the following substances is primarily reabsorbed in the proximal convoluted tubule?

<p>Organic nutrients (D)</p> Signup and view all the answers

What occurs in the descending limb of the nephron loop?

<p>Water leaves the nephron into the bloodstream (B)</p> Signup and view all the answers

Which section of the nephron is primarily responsible for the active secretion of ions and acids?

<p>Distal convoluted tubule (C)</p> Signup and view all the answers

What is the role of the connecting tubules and collecting ducts in the kidney?

<p>Final adjustments to urine concentration (A)</p> Signup and view all the answers

Which anatomical feature of the ureter helps to prevent backflow of urine?

<p>Ureteral openings (B)</p> Signup and view all the answers

In which area of the urinary bladder is the base located in females?

<p>Inferior to the uterus (B)</p> Signup and view all the answers

What distinguishes the male urethra from the female urethra in terms of structure?

<p>It is longer (D)</p> Signup and view all the answers

What type of muscle composes the external urethral sphincter?

<p>Skeletal muscle (C)</p> Signup and view all the answers

What structure transports urine from the kidneys to the urinary bladder?

<p>Ureter (C)</p> Signup and view all the answers

Which of the following statements about the nephron is incorrect?

<p>The nephron exclusively reabsorbs water. (D)</p> Signup and view all the answers

What structure serves as a key component of the outer ear?

<p>Tympanic membrane (B)</p> Signup and view all the answers

Which of the following correctly lists the order of structures that auditory signals pass through from the hair cells to the primary auditory cortex?

<p>Hair cells, inferior colliculi, thalamus (C)</p> Signup and view all the answers

What area surrounding the primary auditory cortex is referred to as the belt?

<p>Secondary auditory cortex (B)</p> Signup and view all the answers

Which structure is primarily responsible for processing auditory signals before they reach the primary auditory cortex?

<p>Inferior colliculi (A)</p> Signup and view all the answers

Which term describes the organization of the auditory cortex that reflects a preference for different frequencies?

<p>Tonotopic organization (C)</p> Signup and view all the answers

What is the primary function of the anterior auditory pathway?

<p>Identifying sounds (D)</p> Signup and view all the answers

What type of damage results in difficulty identifying sounds?

<p>Damage to the anterior pathway (C)</p> Signup and view all the answers

Which type of deafness is caused by damage to the ossicles?

<p>Conductive deafness (A)</p> Signup and view all the answers

Where do auditory-visual interactions primarily occur?

<p>In both primary and association areas (B)</p> Signup and view all the answers

What is a typical effect of age-related hearing loss?

<p>Deficit in perceiving high frequencies (B)</p> Signup and view all the answers

What does the primary sensory cortex primarily receive input from?

<p>The thalamus (B)</p> Signup and view all the answers

Which of the following best describes functional segregation in the sensory system?

<p>Different levels specialize in distinct types of sensory analysis (C)</p> Signup and view all the answers

Parallel processing in sensory systems is characterized by what?

<p>Simultaneous flow of information through multiple pathways (A)</p> Signup and view all the answers

Which type of sensory cortex receives input from more than one sensory system?

<p>Association sensory cortex (A)</p> Signup and view all the answers

How does hierarchical organization function in sensory systems?

<p>Complexity increases as information flows through levels (D)</p> Signup and view all the answers

What is the primary function of the auditory system?

<p>Perceiving and analyzing sound (C)</p> Signup and view all the answers

What does the secondary sensory cortex primarily process?

<p>Input from the primary sensory cortex (B)</p> Signup and view all the answers

What best illustrates the concept of the physical and perceptual dimensions of sound?

<p>Wavelength influences the perceived quality of sound (A)</p> Signup and view all the answers

Flashcards

Cortical Radiate Vein

A vein in the renal cortex that drains blood from the nephrons in the renal cortex.

Cortical Radiate Artery

A branch of an arcuate artery that carries blood to the nephrons in the renal cortex.

Arcuate artery

An artery that arches between the cortex and medulla of the kidney.

Renal Artery

The artery that brings blood to the kidney.

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Nephron

The basic functional unit of the kidney.

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Glomerulus

A network of capillaries in the nephron.

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Afferent Arteriole

The artery leading blood into the glomerulus.

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Renal Vein

The vein that carries filtered blood away from the kidney.

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Glomerular Capillaries

Capillaries forming the glomerulus, responsible for filtration.

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Renal Corpuscle Filtration

Blood pressure pushes fluid and solutes from glomerulus into Bowman's capsule.

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Filtration Layers

Capillary endothelium, basal lamina, and glomerular epithelium layers act as filters.

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Capillary Endothelium

Fenestrated capillaries, preventing blood cells from passing but allowing smaller components.

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Basal Lamina

Layer between capillary and epithelium, restricts large proteins but allows smaller substances.

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Cortical Nephron

A type of nephron located primarily in the cortex of the kidney, comprising 85% of nephrons. They have a short nephron loop.

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Juxtamedullary Nephron

A type of nephron located near the border of the cortex and medulla, comprising 15% of nephrons. They have a long nephron loop.

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Nephron Loop

A U-shaped loop of tubule in nephrons, plays a role in water and solute reabsorption.

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Renal Corpuscle

The initial filtering unit of the nephron, producing glomerular filtrate.

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Glomerular Filtrate

The protein-free solution produced by the glomerulus.

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Glomerular Capsule

Part of the renal corpuscle, it encloses the glomerulus and collects the filtrate.

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Podocytes

Cells in the visceral layer of the glomerular capsule that wrap around the capillaries, helping to filter the blood.

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Urine Processing

The nephron process of reabsorbing needed substances and actively removing waste.

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Urinary System Function: Ion Regulation

The urinary system controls the concentration of crucial ions like sodium, potassium, and chloride in the blood.

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Urinary System Function: Blood Volume/Pressure

The system helps maintain stable blood volume and pressure by regulating water retention or excretion.

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Urinary System Function: pH Regulation

Maintaining the proper acidity (pH) of blood is a major function of the urinary system.

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Urinary System Function: Nutrient Retention

The kidneys prevent the loss of essential nutrients that the body needs.

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Urinary System Function: Waste Elimination

The urinary system removes waste products from the body, including urea.

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Urinary System Function: Vitamin D Synthesis

The kidneys produce an active form of Vitamin D called calcitriol.

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Kidney Location (Right)

The right kidney is situated behind the liver, duodenum, and the hepatic flexure.

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Kidney Location (Left)

The left kidney is positioned higher than the right kidney, and is covered by the stomach, spleen, and pancreas.

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Kidney Structure: Nephron

The functional unit of the kidney responsible for filtering blood and producing urine.

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Kidney Blood Supply

The renal artery and vein carry blood to and from the kidneys.

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Kidney Connective Tissue Layers

Layers of connective tissue, including fibrous capsule, perirenal fat, and renal fascia, surround and protect the kidney.

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Urinary Bladder Function

The urinary bladder temporarily stores urine before elimination.

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Ureter Function

The ureter transports urine from the kidneys to the urinary bladder.

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Kidney Function: Detoxification

The kidneys help the liver with some detoxifying functions.

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Renal Columns

Sections of tissue in the kidney, located between the pyramids.

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Filtration Slits

Gaps between the foot processes of podocytes, forming a barrier that allows water and small solutes to pass through, but restricts large molecules like proteins from entering the filtrate.

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What is the primary function of the glomerular capillaries?

The glomerular capillaries are responsible for forming the initial filtrate from the blood. This filtrate contains water, small solutes, and minimal amounts of plasma proteins.

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What is the role of the basal lamina in filtration?

The basal lamina acts as a selective barrier, preventing large plasma proteins from entering the filtrate. It also provides structural support for the glomerulus.

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What are the key components of the filtration membrane?

The filtration membrane consists of three main components: the capillary endothelium, the basal lamina, and the filtration slits between podocyte foot processes.

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What is the composition of the glomerular filtrate?

The glomerular filtrate is a fluid that is formed by the filtration process in the glomerulus. It consists primarily of water, ions (sodium, potassium, chloride), small organic molecules (glucose, amino acids, fatty acids), and a very small amount of plasma proteins.

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Juxtaglomerular complex

A specialized structure located at the point where the afferent arteriole contacts the distal convoluted tubule of a nephron. It plays a crucial role in regulating blood pressure and filtration rate.

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What are the components of the juxtaglomerular complex?

The juxtaglomerular complex consists of three main components: juxtaglomerular cells, macula densa, and extraglomerular mesangial cells.

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Macula Densa Cells

Specialized cells in the distal convoluted tubule that monitor sodium and chloride ion concentrations in the filtrate.

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Juxtaglomerular Cells

Cells in the walls of the afferent arterioles that secrete renin and erythropoietin.

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Mesangial Cells

Cells found within the glomerulus that provide structural support for the glomerular capillaries and help regulate blood flow.

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Renin

An enzyme secreted by the juxtaglomerular cells that initiates the renin-angiotensin-aldosterone system (RAAS), which regulates blood pressure.

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Erythropoietin

A hormone secreted by the juxtaglomerular cells that stimulates the production of red blood cells in the bone marrow.

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Proximal Convoluted Tubule

The first part of the renal tubule, where most of the water, electrolytes, and nutrients are reabsorbed back into the bloodstream.

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Nephron Loop (Loop of Henle)

A U-shaped portion of the renal tubule that plays a crucial role in concentrating urine by reabsorbing water and ions.

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Distal Convoluted Tubule

The final segment of the renal tubule, where fine-tuning of ion and water reabsorption occurs, and waste products are secreted.

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Collecting Duct

A tube that collects filtrate from multiple nephrons and carries it to the renal pelvis.

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Papillary Duct

The final portion of the collecting duct that delivers concentrated urine into the minor calyx.

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Ureter

A muscular tube that carries urine from the kidneys to the urinary bladder.

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Urinary Bladder

A muscular sac that stores urine before it is eliminated from the body.

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Urethra

A tube that carries urine from the urinary bladder to the outside of the body.

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External Ear

The outermost part of the ear, responsible for collecting sound waves and directing them towards the middle ear.

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Tympanic Membrane

A thin membrane that separates the external ear from the middle ear. It vibrates in response to sound waves, transmitting them to the middle ear.

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Ossicles

Three tiny interconnected bones in the middle ear: the malleus (hammer), incus (anvil), and stapes (stirrup). They amplify and transfer vibrations from the tympanic membrane to the inner ear.

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Cochlea

A spiral-shaped, fluid-filled organ in the inner ear responsible for converting sound vibrations into electrical signals that the brain can understand.

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Hair Cells

Sensory receptors located within the cochlea. They are responsible for converting mechanical energy from sound vibrations into electrical signals.

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What are the three types of sensory cortex?

The three types of sensory cortex are:

  1. Primary sensory cortex: Receives input directly from the thalamus, responsible for initial processing of sensory information.
  2. Secondary sensory cortex: Receives input from the primary sensory cortex, performs more complex analysis of sensory information.
  3. Association sensory cortex: Receives input from multiple sensory systems, integrates information from different senses.
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Hierarchical organization

Hierarchical organization in sensory systems refers to the flow of information through brain structures in order of increasing anatomical complexity. This means that simpler processing occurs in earlier stages, and more complex processing happens in later stages.

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Functional segregation

Functional segregation in sensory systems means that different areas within the brain specialize in processing specific types of information. For example, one area might handle shape recognition, while another handles movement detection.

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Parallel processing

Parallel processing in sensory systems refers to the simultaneous flow of information along multiple pathways. This allows the brain to process different aspects of a sensory stimulus at the same time, leading to faster and more efficient processing.

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What are the physical and perceptual dimensions of sound?

The physical dimensions of sound are:

  1. Frequency: The rate of vibration, perceived as pitch (high or low).
  2. Amplitude: The intensity of vibration, perceived as loudness.
  3. Complexity: The combination of different frequencies, perceived as timbre (quality of sound).
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What are the components of the human ear?

The human ear is divided into three main parts:

  1. Outer ear: Collects sound waves and directs them to the eardrum.
  2. Middle ear: Amplifies sound waves and transmits them to the inner ear.
  3. Inner ear: Contains the cochlea, which converts sound waves into electrical signals that the brain can interpret.
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Describe the major pathways leading from the ear to the primary auditory cortex.

The major pathways leading from the ear to the primary auditory cortex are:

  1. Auditory nerve: Carries electrical signals from the cochlea to the brainstem.
  2. Cochlear nuclei: Relay stations in the brainstem that receive input from the auditory nerve.
  3. Superior olivary nuclei: Involved in sound localization.
  4. Inferior colliculus: Relay station in the midbrain.
  5. Medial geniculate nucleus: Relay station in the thalamus.
  6. Primary auditory cortex: The first cortical area to receive auditory information.
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What are the effects of damage to the auditory system?

Damage to the auditory system can lead to a range of hearing impairments, including:

  1. Conductive hearing loss: Damage to the outer or middle ear, preventing sound waves from reaching the inner ear.
  2. Sensorineural hearing loss: Damage to the inner ear, including the cochlea or auditory nerve.
  3. Tinnitus: A ringing or buzzing sound in the ears, often caused by damage to the auditory system.
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Auditory Cortex Pathways

There are two main pathways in the auditory cortex: the anterior pathway, which identifies sounds, and the posterior pathway, which identifies the location of sounds.

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Auditory-Visual Interactions

Information from the auditory and visual systems is integrated in the brain, allowing us to perceive the world in a rich and multi-sensory way. This often happens in association areas but can also occur even in primary sensory areas.

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Anterior Auditory Pathway Damage

Damage to the anterior auditory pathway can lead to difficulty identifying sounds.

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Posterior Auditory Pathway Damage

Damage to the posterior auditory pathway can make it hard to locate sounds.

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Types of Deafness

There are two main types of deafness: conductive deafness, caused by damage to the ossicles in the middle ear, and nerve deafness, caused by damage to the cochlea or auditory nerve.

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Study Notes

Urinary System Overview

  • The urinary system is responsible for functions such as regulating plasma ion concentrations (Na+, K+, Cl-), blood volume and blood pressure, stabilizing blood pH, preventing the loss of nutrients, eliminating organic waste (urea), synthesizing calcitriol (active vitamin D), and preventing dehydration, and aiding liver functions.

Urinary System Components

  • Kidneys: Produce urine.
  • Ureters: Transport urine to the bladder.
  • Urinary Bladder: Temporarily stores urine, prior to elimination.
  • Urethra: Conducts urine to the exterior and, in males, also transports semen

Kidneys

  • Location: The right kidney is covered by the liver, hepative flexure and the duodenum and the left kidney is covered by the spleen, stomach, and pancreas. The left kidney is positioned higher than the right kidney due to the liver. Both are capped by suprarenal glands.

  • Structure: Have a cortex and medulla. Contain nephrons, the functional units of the kidneys.

  • Blood Supply: The renal artery is on top of the renal vein. Blood flows through a series of arteries. -Renal artery → Segmental arteries→ Interlobar arteries → Arcuate arteries → Cortical radiate arteries

  • Blood Supply(veins): Renal vein → Interlobar veins → Arcuate veins → Cortical radiate veins

Nephron

  • Structure: A long tubular passageway with a glomerulus (intertwining capillaries) and renal tubule
  • Function: Reabsorbs useful organic materials and water, and secretes waste into the filtrate. Two main groups of nephrons exist: cortical and juxtamedullary.
  • Cortical Nephrons: Majority (85%) of the nephrons. They have a short nephron loop.
  • Juxtamedullary Nephrons: 15% of the nephrons, positioned close to the border of the cortex and medulla, and have long nephron loops.
  • Components: Proximal convoluted tubule, nephron loop (descending and ascending limbs), distal convoluted tubule, and collecting duct.

Renal Corpuscle

  • Structure: Formed by two parts:
    • Glomerular capsule (Bowman's capsule): Double-walled hollow structure that surrounds the glomerulus, the inner layer is the visceral layer and is made up of cells that cover the capillaries and are called Podocytes. the outer layer is called the parietal layer, and wraps around the proximal convoluted tubule.
    • Glomerular capillaries (glomerulus): Fenestrated capillaries (pores) that allow for the filtration of blood.
  • Filtration: Blood pressure forces fluid and dissolved solutes (ions, glucose, amino acids, vitamins, etc.) from the glomerulus into the capsular space within the glomerular capsule.
  • Filtration Membrane: Three layers that filter blood in the renal corpuscle: capillary endothelium, basal lamina, and glomerular epithelium. Each layer has selective permeability that blocks bigger elements such as plasma proteins, cells and blood.

Filtration Membrane Layers

  • Capillary endothelium: Fenestrated (porous) capillaries prevent blood cells from passing through.
  • Basal lamina: Resists large proteins but allows smaller proteins and nutrients to pass.
  • Glomerular epithelium (podocytes): Has filtration slits among cellular extensions to keep large proteins out of the filtrate.

Proximal Convoluted Tubule

  • Reabsorption: Reabsorbs all organic nutrients, plasma proteins, 60% of the sodium and chloride ions and water, calcium, potassium, magnesium, bicarbonate, and sulfate ions.

Nephron Loop

  • Descending limb: Water moves out of the descending limb.
  • Ascending limb: Pumps sodium and chlorine out of the thick ascending limb.

Distal Convoluted Tubule

  • Function: Selectively reabsorb sodium and calcium ions. Reabsorption of water can occur, and secretion (removal) of ions and acids.

Collecting System

  • Structure: Consists of connecting tubules, collecting ducts, and papillary ducts
  • Function: Transports filtrate. A final regulation of urine concentration takes place in the DCT and collecting duct.

Urinary Bladder

  • Location (Male): Between the rectum and the symphysis pubis
  • Location (Female): Below the uterus and in front of the vagina
  • Function: Temporarily stores urine.

Ureters

  • Purpose: Transport urine from the kidneys to the urinary bladder.
  • Anatomy: Muscles in the walls contract, forcefully pushing urine to the bladder.

Urethra

  • Male: 18-20 cm long and has three subdivisions: prostatic urethra, membranous urethra, and spongy urethra (part that passes through the penis).
  • Female: 3-5 cm long and exists only to pass urine to the outside of the body.
  • Sphincters: This structure prevents the passage of urine at will. These are muscles and are under conscious control (voluntary).

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Explore the functions and key components of the urinary system, including the roles of the kidneys, ureters, bladder, and urethra. This quiz will test your knowledge on how these organs work in regulating bodily functions and maintaining homeostasis.

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