Urinary System Case: Chronic Kidney Disease

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Questions and Answers

What percentage of cardiac output does the kidney receive?

  • 30-35%
  • 20-25% (correct)
  • 40-45%
  • 10-15%

What is the function of the Macula densa?

  • To sense the NaCl concentration in the tubular fluid (correct)
  • To control the renal blood flow
  • To regulate the glomerular filtration rate
  • To reabsorb electrolytes in the proximal tubule

What is the name of the vessel that supplies blood to the kidney?

  • Peritubular capillaries
  • Renal vein
  • Renal artery (correct)
  • Renal hilum

Which of the following is NOT a function of the renal system?

<p>Digestion of proteins (B)</p> Signup and view all the answers

What is the name of the structure that surrounds the glomerulus?

<p>Bowman's capsule (A)</p> Signup and view all the answers

What percentage of nephrons are juxtamedullary nephrons?

<p>20-30% (B)</p> Signup and view all the answers

What is the primary function of the renal system's excretion?

<p>Removal of waste and foreign products from the blood (B)</p> Signup and view all the answers

What is the term for the functional unit of the kidney?

<p>Nephron (D)</p> Signup and view all the answers

What is the location of the juxtamedullary nephrons?

<p>Border of the cortex and medulla (D)</p> Signup and view all the answers

What is the function of the peritubular capillaries?

<p>Reabsorption of electrolytes and water (D)</p> Signup and view all the answers

What is the name of the vessel that receives the filtered blood from the glomerulus?

<p>Efferent arteriole (C)</p> Signup and view all the answers

What is the term for the process by which the kidney regulates blood pressure?

<p>Renin-angiotensin-aldosterone system (RAAS) (B)</p> Signup and view all the answers

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Study Notes

Functions of the Renal System

  • Excretes waste and foreign products
  • Regulates blood electrolytes, pH, blood volume, and pressure
  • Produces hormones such as Erythropoietin, Vitamin D, and Renin
  • Assists in blood glucose level regulation
  • Transports and stores urine in the lower urinary tract

Anatomy of the Urinary System

  • Kidney: paired organs located in the retroperitoneum, right kidney is lower than left
  • Divided into cortex and medulla
  • Consists of 1 million nephrons per kidney
  • Renal Papilla, Minor and Major Calyx, and Renal Pelvis are part of the kidney structure
  • Supplied by renal artery and vein, receiving 20-25% of cardiac output
  • Has two sets of capillaries: arterioles and vasa recta

Nephron: Functional Unit

  • 1.2 million nephrons per kidney, cannot be replaced
  • Consists of Renal Corpuscle and Renal Tubules
  • Two types of nephrons: Cortical (70-80%) and Juxtamedullary (20-30%)

Nephron: Renal Corpuscle

  • Glomerulus: a cluster of capillaries surrounded by podocytes
  • Glomerular capillaries are fenestrated
  • Bowman's capsule and Bowman's space are part of the glomerulus

Nephron: Renal Tubules

  • Proximal Tubule: 65% reabsorptive capacity, majority of electrolytes reabsorbed
  • Loop of Henle: descending limb permeable to water, ascending limb permeable to solutes
  • Distal Convoluted Tubule: divided into early and late, senses NaCl concentration
  • Collecting Duct: cortical and medullary parts, regulated by juxtaglomerular cells

Urine Formation

  • Process: filtration, reabsorption, secretion, and excretion
  • Glomerular Filtration Barrier: podocytes, glomerular capillaries, and Bowman's capsule
  • Net Filtration Pressure: determines the rate of filtration

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