Podcast Beta
Questions and Answers
The alteration of _____________ pH is important in pharmacology.
urinary
Drugs for _____________ are used to increase drug elimination in overdose.
alkalinization
In acidic pH, an _____________ drug becomes ionized.
acidic
Alkaline diuresis is used to remove _____________ drugs from the body.
Signup and view all the answers
Phenobarbitone is an example of a drug that undergoes _____________ diuresis.
Signup and view all the answers
Increasing the pH of urine can increase the efficacy of _____________ in the urine.
Signup and view all the answers
Shimaa Mohamed Elkholy is a professor in the _____________ department.
Signup and view all the answers
Drugs for _____________ are used to increase the elimination of basic drugs from the body.
Signup and view all the answers
Aminoglycosides are classified as ________ antibiotics.
Signup and view all the answers
To discourage the growth of certain urinary pathogen, ________ of urine is necessary.
Signup and view all the answers
Symptomatic relief of cystitis can be achieved through ________ of urine.
Signup and view all the answers
Sulfonamide is an example of a drug that requires ________ of urine.
Signup and view all the answers
To reduce stone formation, ________ of urine is necessary for urate stones.
Signup and view all the answers
Sodium bicarbonate is a drug used for ________ of urine.
Signup and view all the answers
Acetazolamide is a drug used for ________ of urine.
Signup and view all the answers
Acidification of urine is necessary for ________ stones.
Signup and view all the answers
Study Notes
Importance of Urinary pH
- Alkaline or acidic diuresis can increase drug elimination in overdose cases
- Acidic diuresis is used for acidic drugs, while alkaline diuresis is used for basic drugs
Examples of Drugs
- Acidic drugs: phenobarbitone, salicylate, aspirin, pethidine
- Basic drugs: amphetamines, ephedrine
Importance of Urinary pH in Antimicrobial Efficacy
- Alkaline urine increases the efficacy of antimicrobials such as aminoglycosides, tetracycline, erythromycin, penicillins, nitrofurantoin, and cephalosporins
Importance of Urinary pH in Discouraging Growth of Urinary Pathogens
- Alkaline urine discourages the growth of E. coli
Importance of Urinary pH in Symptomatic Relief of Cystitis
- Alkaline urine provides symptomatic relief of cystitis
Importance of Urinary pH in Preventing Crystalluria
- Alkaline urine prevents crystalluria of sulfonamide
- Acidic urine prevents crystalluria of urate
- Alkaline urine prevents crystalluria of phosphate
Drugs for Alkalinization
- Sodium bicarbonate
- Sodium lactate
- Sodium or potassium citrate
- Acetazolamide
Drugs for Acidification
- (No specific drugs mentioned)
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
This quiz covers the importance of urinary pH alteration, drugs for alkalinization and acidification. It is an essential topic in clinical pharmacology.
