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Urinary Antiseptics, Disinfectants, and Sterilants

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Urinary Antiseptics, Disinfectants, and Sterilants

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Questions and Answers

What is the primary mechanism of action of urinary antiseptics in the treatment of UTIs?

Reducing the pH of urine

Boosting the immune system

Systemic antibacterial effects

Inhibiting bacterial growth in urine (correct)

What is the common practice when administering urinary antiseptics?

Administering with antibiotics to enhance effects

Administering with probiotics to promote gut health

Administering with alkalizing agents to increase pH

Administering with acidifying agents to lower pH (correct)

Which of the following bacteria is not susceptible to nitrofurantoin?

E. coli

Staphylococcus saprophyticus

Proteus (correct)

Pseudomonas aeruginosa

What is the primary characteristic of urinary antiseptics?

Rapid excretion into the urine Signup and view all the answers

Why do urinary antiseptics lack systemic antibacterial effects?

They are excreted too rapidly Signup and view all the answers

What is the primary mechanism by which nalidixic acid acts against gram-negative organisms?

Inhibition of DNA gyrase Signup and view all the answers

Which of the following drugs is NOT active against Proteus?

Methenamine mandelate Signup and view all the answers

What is the consequence of combining methenamine with sulfonamides?

Formation of insoluble complexes Signup and view all the answers

What is the primary route of excretion of nalidixic acid?

Renal excretion via filtration and secretion Signup and view all the answers

What is a common adverse effect of nitrofurantoin?

Gastrointestinal irritation Signup and view all the answers