Urinary Antiseptics, Disinfectants, and Sterilants

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Questions and Answers

What is the primary mechanism of action of urinary antiseptics in the treatment of UTIs?

  • Reducing the pH of urine
  • Boosting the immune system
  • Systemic antibacterial effects
  • Inhibiting bacterial growth in urine (correct)

What is the common practice when administering urinary antiseptics?

  • Administering with antibiotics to enhance effects
  • Administering with probiotics to promote gut health
  • Administering with alkalizing agents to increase pH
  • Administering with acidifying agents to lower pH (correct)

Which of the following bacteria is not susceptible to nitrofurantoin?

  • E. coli
  • Staphylococcus saprophyticus
  • Proteus (correct)
  • Pseudomonas aeruginosa

What is the primary characteristic of urinary antiseptics?

<p>Rapid excretion into the urine (A)</p> Signup and view all the answers

Why do urinary antiseptics lack systemic antibacterial effects?

<p>They are excreted too rapidly (C)</p> Signup and view all the answers

What is the primary mechanism by which nalidixic acid acts against gram-negative organisms?

<p>Inhibition of DNA gyrase (C)</p> Signup and view all the answers

Which of the following drugs is NOT active against Proteus?

<p>Methenamine mandelate (B)</p> Signup and view all the answers

What is the consequence of combining methenamine with sulfonamides?

<p>Formation of insoluble complexes (D)</p> Signup and view all the answers

What is the primary route of excretion of nalidixic acid?

<p>Renal excretion via filtration and secretion (C)</p> Signup and view all the answers

What is a common adverse effect of nitrofurantoin?

<p>Gastrointestinal irritation (C)</p> Signup and view all the answers

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