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Questions and Answers
What is the primary source of uric acid in the body?
What is the primary source of uric acid in the body?
Which of the following statements about uric acid is true?
Which of the following statements about uric acid is true?
How much uric acid does the body typically produce each day?
How much uric acid does the body typically produce each day?
In what form is uric acid predominantly found in plasma?
In what form is uric acid predominantly found in plasma?
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Where in the body is a significant amount of uric acid turnover occurring?
Where in the body is a significant amount of uric acid turnover occurring?
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Study Notes
Uric Acid Metabolism
- Uric acid is the final product of purine metabolism in the liver.
- Purines include adenine and guanine, components of RNA and DNA.
- Uric acid production also results from the high turnover of nucleoproteins in bone marrow and the gastrointestinal tract (GIT). These nucleoproteins contain purines and pyrimidines.
- Uric acid exists as monosodium salt in plasma.
- The total body pool of uric acid is approximately 1200 mg.
- About half of the uric acid pool (600 mg) is turned over daily.
- Approximately 600 mg of uric acid is produced daily.
- An equivalent amount of 600 mg is lost daily.
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Description
This quiz covers the key aspects of uric acid metabolism, focusing on its production as the end product of purine metabolism in the liver. Explore how various components such as nucleoproteins and daily turnover contribute to the body's uric acid levels.
