Urea Cycle Reactants and Enzymes Quiz
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Questions and Answers

Where does the first reaction of the urea cycle take place?

  • Golgi apparatus
  • Mitochondria (correct)
  • Endoplasmic reticulum
  • Cytosol

    • What is the activator of Carbamoyl phosphate synthetase I (CPS I)?

  • N-Acetyl-Glutamate (correct)
  • Carbamoyl phosphate
  • Ornithine
  • Argininosuccinate

    • Which syndrome is caused by the mutation of the ornithine transport gene?

  • Huntington's disease
  • HHH syndrome (correct)
  • Marfan syndrome
  • Turner syndrome

    • What is the product formed when citrulline reacts with 1 more ammonia from Aspartic acid in the cytosol?

    <p>Argininosuccinate</p> Signup and view all the answers

    Why do we still need to get ornithine from the diet if it is immediately converted to urea?

    <p>For protein synthesis</p> Signup and view all the answers

    Which enzyme catalyzes the conversion of arginine to urea and ornithine in the urea cycle?

    <p>Arginase</p> Signup and view all the answers

    What is the immediate consequence of the deficiency of any enzyme in the urea cycle?

    <p>Hyperammonemia</p> Signup and view all the answers

    Which step in the urea cycle involves the detoxification of 1 mole of ammonia?

    <p>1st reaction catalyzed by CPS I</p> Signup and view all the answers

    Which molecule is NOT produced as a direct result of the urea cycle?

    <p>Fumarate</p> Signup and view all the answers

    What is the total amount of ATP consumed in both the 1st and 3rd reactions of the urea cycle?

    <p>4 moles of ATP</p> Signup and view all the answers

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