Podcast
Questions and Answers
Which complication is primarily associated with upper tract renal conditions?
Which complication is primarily associated with upper tract renal conditions?
- General malaise (correct)
- Chronic pain
- Dehydration
- Lower tract infections
What is a common symptom of conditions affecting the upper tract, such as a cut pyelonephritis?
What is a common symptom of conditions affecting the upper tract, such as a cut pyelonephritis?
- Fever (correct)
- Hematuria
- Costovertebral angle tenderness
- Dysuria
Which of the following is least likely to be a symptom of upper tract renal conditions?
Which of the following is least likely to be a symptom of upper tract renal conditions?
- Vomiting
- Loin pain
- Urgency (correct)
- Nausea
In comparing upper and lower tract issues, which symptom is more indicative of a lower tract problem?
In comparing upper and lower tract issues, which symptom is more indicative of a lower tract problem?
What type of renal trauma is more consistent with a cut affecting the upper tract?
What type of renal trauma is more consistent with a cut affecting the upper tract?
Which combination of substances is considered appropriate for treating certain infections?
Which combination of substances is considered appropriate for treating certain infections?
What is the effective duration of treatment for lower tract and upper tract infections?
What is the effective duration of treatment for lower tract and upper tract infections?
What is the minimal course duration recommended for certain types of infections?
What is the minimal course duration recommended for certain types of infections?
Which class of antibiotics is mentioned for use in conjunction with ceftriaxone?
Which class of antibiotics is mentioned for use in conjunction with ceftriaxone?
Which of the following antibiotics would NOT be used alone for treating the specified infections?
Which of the following antibiotics would NOT be used alone for treating the specified infections?
Which method is stated to be faster and less expensive compared to urinalysis?
Which method is stated to be faster and less expensive compared to urinalysis?
What is indicated about urine culture in children under 2 years of age?
What is indicated about urine culture in children under 2 years of age?
What is a significant limitation of urinalysis when used for infants?
What is a significant limitation of urinalysis when used for infants?
What type of evidence does urinary tract symptoms provide?
What type of evidence does urinary tract symptoms provide?
Why might urine culture be considered avoidable?
Why might urine culture be considered avoidable?
In what scenario does the necessity for urinalysis increase?
In what scenario does the necessity for urinalysis increase?
During which circumstance might the leukocyte esterase activity test be particularly advantageous?
During which circumstance might the leukocyte esterase activity test be particularly advantageous?
What does lower sensitivity in urinalysis for infants suggest about its use?
What does lower sensitivity in urinalysis for infants suggest about its use?
What is a potential consequence of urinary obstruction as mentioned in the content?
What is a potential consequence of urinary obstruction as mentioned in the content?
Which mechanism is likely involved in the development of urinary issues according to the passage?
Which mechanism is likely involved in the development of urinary issues according to the passage?
What may result from inadequate habit formation related to urinary health?
What may result from inadequate habit formation related to urinary health?
Which of the following is not indicated as a risk factor associated with urinary issues?
Which of the following is not indicated as a risk factor associated with urinary issues?
An important factor to be aware of concerning urinary tract conditions is:
An important factor to be aware of concerning urinary tract conditions is:
What is a likely lifestyle effect mentioned regarding urinary health?
What is a likely lifestyle effect mentioned regarding urinary health?
Which bacterial condition is referenced as a potential contributing factor to urinary tract issues?
Which bacterial condition is referenced as a potential contributing factor to urinary tract issues?
In the context of urinary issues, what role does the lower urinary tract play?
In the context of urinary issues, what role does the lower urinary tract play?
What should be performed for all children after the first proven UTI?
What should be performed for all children after the first proven UTI?
Which factor is NOT taken into account when deciding on subsequent investigations after an initial UTI?
Which factor is NOT taken into account when deciding on subsequent investigations after an initial UTI?
What percentage of children with a history of UTI are found to have VUR?
What percentage of children with a history of UTI are found to have VUR?
Why might renal scarring occur in children with UTIs?
Why might renal scarring occur in children with UTIs?
What does a negative combination diagnostic result imply regarding UTIs in infants?
What does a negative combination diagnostic result imply regarding UTIs in infants?
In the context of investigating UTIs, how should subsequent investigations be tailored?
In the context of investigating UTIs, how should subsequent investigations be tailored?
What is a common misconception regarding VUR and renal scarring?
What is a common misconception regarding VUR and renal scarring?
What combination of factors is critical for assessing a child's condition after a UTI?
What combination of factors is critical for assessing a child's condition after a UTI?
What is a potential complication associated with severe obstruction during the neonatal period?
What is a potential complication associated with severe obstruction during the neonatal period?
Which diagnostic method is used to establish a diagnosis of urinary obstruction?
Which diagnostic method is used to establish a diagnosis of urinary obstruction?
What is the consequence of inserting a Foley catheter into the bladder of a healthy neonate?
What is the consequence of inserting a Foley catheter into the bladder of a healthy neonate?
What should not be used in neonates for urinary obstruction due to the risk of severe bladder complications?
What should not be used in neonates for urinary obstruction due to the risk of severe bladder complications?
When is the preferred management approach for treating urethral stricture in neonates?
When is the preferred management approach for treating urethral stricture in neonates?
What is a common long-term issue as a result of less severe urinary obstruction in children?
What is a common long-term issue as a result of less severe urinary obstruction in children?
What treatment is suggested when serum creatinine levels are normal in cases of obstruction?
What treatment is suggested when serum creatinine levels are normal in cases of obstruction?
What complication might occur if the urethra is too small in a neonate?
What complication might occur if the urethra is too small in a neonate?
What is the risk of using a Foley catheter for an extended period in a neonate?
What is the risk of using a Foley catheter for an extended period in a neonate?
What type of imaging may be used to assess urinary obstruction via perineal assessment?
What type of imaging may be used to assess urinary obstruction via perineal assessment?
What is a common presentation of neonates suffering from urinary obstruction?
What is a common presentation of neonates suffering from urinary obstruction?
What is the risk associated with not treating urinary obstruction promptly in neonates?
What is the risk associated with not treating urinary obstruction promptly in neonates?
What form of treatment is essential in controlling infection associated with urinary obstruction?
What form of treatment is essential in controlling infection associated with urinary obstruction?
Flashcards
Complete Blood Count (CBC)
Complete Blood Count (CBC)
A test used to measure white blood cells, which are important for fighting off infections.
Urine Leukocyte Test
Urine Leukocyte Test
A test specifically looking for the presence of white blood cells in urine.
Sensitivity Testing
Sensitivity Testing
A test used to assess the effectiveness of antibiotics in treating bacterial infections.
Culture and Sensitivity Test
Culture and Sensitivity Test
Signup and view all the flashcards
Microscopy
Microscopy
Signup and view all the flashcards
Fever
Fever
Signup and view all the flashcards
Infection Detection
Infection Detection
Signup and view all the flashcards
Symptom Complex
Symptom Complex
Signup and view all the flashcards
Vesicoureteral Reflux (VUR)
Vesicoureteral Reflux (VUR)
Signup and view all the flashcards
Uropathogenic Bacteria
Uropathogenic Bacteria
Signup and view all the flashcards
Urinary Tract Defense Mechanisms
Urinary Tract Defense Mechanisms
Signup and view all the flashcards
Urinary Frequency
Urinary Frequency
Signup and view all the flashcards
Incomplete Bladder Emptying
Incomplete Bladder Emptying
Signup and view all the flashcards
Urinary Incontinence
Urinary Incontinence
Signup and view all the flashcards
Impaired Urinary Tract Defense
Impaired Urinary Tract Defense
Signup and view all the flashcards
Bacterial Colonization
Bacterial Colonization
Signup and view all the flashcards
Short course of antibiotics
Short course of antibiotics
Signup and view all the flashcards
Standard course of antibiotics
Standard course of antibiotics
Signup and view all the flashcards
Amoxicillin
Amoxicillin
Signup and view all the flashcards
Cefaclor
Cefaclor
Signup and view all the flashcards
Upper Tract
Upper Tract
Signup and view all the flashcards
Lower Tract
Lower Tract
Signup and view all the flashcards
Urinary Tract Infection (UTI)
Urinary Tract Infection (UTI)
Signup and view all the flashcards
Flank Pain
Flank Pain
Signup and view all the flashcards
Culture and Sensitivity Testing
Culture and Sensitivity Testing
Signup and view all the flashcards
Urinary Tract Obstruction
Urinary Tract Obstruction
Signup and view all the flashcards
Voiding Cystourethrogram (VCUG)
Voiding Cystourethrogram (VCUG)
Signup and view all the flashcards
Ultrasonography
Ultrasonography
Signup and view all the flashcards
Cystoscopy
Cystoscopy
Signup and view all the flashcards
Foley Catheter
Foley Catheter
Signup and view all the flashcards
Obstruction Relief
Obstruction Relief
Signup and view all the flashcards
Urinary Diversion
Urinary Diversion
Signup and view all the flashcards
Antibiotic Prophylaxis
Antibiotic Prophylaxis
Signup and view all the flashcards
Study Notes
Urinary Tract Infections (UTIs) in Childhood
- UTIs are common bacterial infections in children, affecting 8% of girls and 1% of boys in the first 10 years of life.
- Females are predominantly affected, except in the first six months.
- Recurrence rates are 50% in girls and 15% in boys.
- Fever is present in 50% of cases.
Diagnosis
- Urine microbiology is the basis of diagnosis.
- Midstream urine sample (MSSU) or clean-catch urine (CCU) are preferred, with >105 colony-forming units (CFU)/mL indicating infection.
- If clinical urgency exists, suprapubic aspiration or urethral catheterization may be used, aiming for >10³ CFU/mL.
- Urine collected in adhesive bags or pads is prone to contamination.
Pyuria
- Pyuria (presence of white blood cells in urine) is a useful rapid investigation.
-
10 white blood cells/mm³ in boys, and > 50/mm³ in girls, is a helpful indicator of UTI.
- Pyuria may be absent in 25% of recurrent UTIs.
- Pyuria isn't always indicative of significant bacteruria (bacteria in urine).
Leucocyte Esterase and Nitrite
- Combination dipstick urinalysis (measuring leucocyte esterase and nitrite) is faster and less expensive than microscopy.
- Absence in children older than 2 years can make Urine culture potentially avoidable.
- This is because urinary tract symptoms become a more reliable indication of infection in older individuals.
- Sensitivity is lower in infants.
Infectious Agents
- Escherichia coli is the leading cause of community-acquired UTIs in children (up to 75%).
- Enterococci, Klebsiella, Proteus, Serratia, and others account for the remainder.
- UTIs usually ascend from the urethra, with urinary stasis (urine retention) contributing to risk.
Conditions Contributing to UTIs
- Anatomical obstructions
- Vesicoureteric reflux (VUR)
- Incomplete or inefficient voiding habits
- Low fluid intake
- Constipation
Upper and Lower Tract UTIs
- Upper tract: Fever, lethargy, general malaise, vomiting, loin pain.
- Lower tract: dysuria, urgency, frequency, wetting, frank haematuria, non-specific abdominal pain.
Treatment
- Antibiotics should initially be selected based on a educated guess, followed by culture and sensitivity.
- Oral administration (Trimethoprim, Co-amoxiclav, Nitrofurantoin, Cephradine)
- IV therapy may be required in infants and young children , more seriously ill or those who aren't responding.
- Third-generation cephalosporins (cefotaxime, ceftazidime, ceftriaxone) or aminoglycoside and amoxicillin combinations can be used in hospitalized patients
- Antibiotics are given for 7-10 days for both upper and lower tracts.
- Prophylaxis may be needed until the urinary tract is fully investigated.
Vesicoureteric Reflux (VUR)
- Retrograde flow of urine from bladder to ureter.
- Common in UTI patients (30%).
- Occurs in ~1% of healthy neonates.
- Related to underlying conditions such as urethral obstruction or neuropathic bladder dysfunction.
Long-Term Implications
- Children with high-grade VUR with scarring, and those with high-grade VUR with malformations might have long-term complications such as acute pyelonephritis.
- Data suggest risk of hypertension or chronic renal insufficiency with bilateral renal scarring but is limited likely occurs only in those with renal dysplasia.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Related Documents
Description
Test your knowledge on renal conditions affecting the upper and lower tracts. This quiz covers symptoms, complications, and treatments associated with various renal issues, emphasizing effective antibiotic usage. Challenge yourself with questions that differentiate between upper and lower tract symptoms and their management.