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Questions and Answers

Match an active form of vitamin A to its specific function:

Retinol = a product of beta-carotene degeneration Retinoic acid = a metabolite of vitamin A required for degeneration of epithelial cells in conjunctiva Retinal = a light sensitive photochrome

Light if brought to focus behind the retina in this visual deficit, such that in the absence of the powerful accomodation response, it is difficult to focus clearly on nearby objects

  • astigmatism
  • binasal hemianopia
  • hyperopia (correct)
  • myopia
  • bitemporal hemianopia

Small firm nodule was excised in the left hand during surgical procedure. Conclusion of pathology report: neurofibroma. Most likely, morphologic features visible by light microscopy in this case:

  • palisading pattern
  • small cells with elongated nuclei (correct)
  • wavy pattern (correct)
  • acellular areas
  • glomeruloid vascular proliferation
  • psammoma bodies

Light shining on the retina will result in which of the following events?

  1. Synthesis of rhodopsin from vitamin A
  2. Hydrolysis of cyclic GMP
  3. Generation of action potentials by rod photoreceptors
  4. Hyperpolarization of cone photoreceptors

<p>All are correct (@)</p> Signup and view all the answers

This structure, which receives afferents traveling in the inferior brachium, has projections to the superior temporal gyrus

<p>Medial geniculate nucleus (A)</p> Signup and view all the answers

By which feature the receptive fields of the simple cortical cells differ from those of LGN ones?Select one:

<p>Orientation tuning (B)</p> Signup and view all the answers

A person has unilateral hearing loss. Based only on this limited amount of information, which of the following statements best indicates a likely site of lesion? Select one:

<p>Acoustic division of the eighth cranial nerve (B)</p> Signup and view all the answers

Constriction of the pupil

  1. Is mediated via sympathetic nerves
  2. Can be elicited by light directed into one eye the optic nerve of which is cut
  3. Increases the refractive power of the eye
  4. Improves visual acuity

<p>4 is correct (A)</p> Signup and view all the answers

The focal length of the convex lens is 20 cm. At what distance from the lens should the object be so that the image size is the same as object size?

<p>40 cm (B)</p> Signup and view all the answers

Which of the statements are correct describing phenomenon of neuroinflamation? Select one or more:

<p>Microglial cells are involved in neuroinflammatory response in the brain (A), Excessive production of reactive oxygen species may occur during neuroinflammation (B)</p> Signup and view all the answers

Assign the properties of photoreceptors to either rods or cones.

<p>The location is in the periphery of the retina. = Rods Do not mediate color vision. = Rods Active at higher light levels = Cones The visual pigment is iodopsin. = Cones</p> Signup and view all the answers

Which of the following statements about mechanism of light-induced signaling in retina is correct? Select one or more:

<p>In response to light, a release of neurotransmitter glutamate is increased from a photoreceptor (B), Under illumination, concentration of Ca ions decreases in a photoreceptor (C)</p> Signup and view all the answers

Which nucleus is damaged in Alzheimer's disease that projects cholinergic fibers to the cerebral cortex? Select one:

<p>substantia innominata (C)</p> Signup and view all the answers

Which statement (s) about olfactory sensory cells is (are) correct? Select one or more:

<p>They are modified bipolar neurons (A), They contain cilia (C), They can be renewed (D)</p> Signup and view all the answers

What is the standing wave?

<p>A wave that oscillates in time but whose peak amplitude profile does not move in space (A)</p> Signup and view all the answers

An encapsulated firm nodule of 1.3 cm excised from left forearm area during surgical procedure is examined by light microscopy: mixed areas of increased and decreased cellularity, also palisading pattern of neoplastic cells, rare mitoses are observed, no necrosis, no glomeruloid vascular proliferation are detected. Most likely it is:

<p>schwannoma (A)</p> Signup and view all the answers

Cortical area receiving input from the medial geniculate body is: Select one:

<p>primary auditory cortex (B)</p> Signup and view all the answers

Sectioning of the mammillothalamic tract is likely to inhibit affrents to which of the following parts of the thalamus? Select one:

<p>anterior nuclear group (C)</p> Signup and view all the answers

In case of convex lens, the ray parallel to the principal optical axis after refraction goes trough:

<p>the focus point of the lens (D)</p> Signup and view all the answers

Axons of the retinal ganglion neurons project mainly to the: Select one:

<p>lateral geniculate body (B)</p> Signup and view all the answers

Testing revealed blindness in the right eye; arteriograms of the circle of Willis and cerebral arterial supply showed a complete occlusion of the right internal carotid artery where it lyies within the cavernous sinus. This is due to decreased perfusion through wich branch of the internal carotid artery? Select one:

<p>ophthalmic (D)</p> Signup and view all the answers

During accommodation for near vision:

  1. The ciliary muscle constricts
  2. The tension on lens ligaments increases
  3. The curvature of the lens increases
  4. The pupil dilates

<p>1 and 3 are correct (B)</p> Signup and view all the answers

In which manner the cells with spectral (color) selectivity are distributed in the primary visual cortex? Select one:

<p>Forming the blobs in the II and III layers (D)</p> Signup and view all the answers

The otolith organs are responsible for ➢ producing the vestibular-ocular reflex ➢ producing rotatory nystagmus ➢ detecting angular acceleration ➢ detecting the position of the head in space

<p>4 is correct (B)</p> Signup and view all the answers

The optical system of eye is considered to be:

<p>Variable focus length convex lens (C)</p> Signup and view all the answers

What image will be formed with a convex lens, if the object is between single and double focal length?

<p>real, inverted, and magnified (C)</p> Signup and view all the answers

Which definition of the node of the standing wave is incorrect?

<p>The nodes are the points along the medium that undergo vibrations between a large positive and large negative displacement (C)</p> Signup and view all the answers

Which structure is NOT part of the Papez circuit?

<p>Nucleus caudatus (@)</p> Signup and view all the answers

What kind of waves can form the standing wave?

<p>All types of mechanical and electromagnetic waves (C)</p> Signup and view all the answers

30 years old male patient was diagnosed with von Hippel - Lindau disease. Most likely the diagnosed disease of this patient may have manifested with:

<p>mediastinal paraganglioma (C), spinal cord hemangioblastoma (@)</p> Signup and view all the answers

Which of the following statements about a vitamin A are correct?

<p>Vitamin A is a precursor of cis retinal, which is an integral part of the photopigment rhodopsin (A), The deficiency of vitamin A cause night blindness by affecting rods response of dark adaptation and scotopic vision (D)</p> Signup and view all the answers

The anterior cerebral artery supplies all of the following structures except:

<p>Wernicke area (C)</p> Signup and view all the answers

Which of the following statements about mechanism of light induced signaling in retina is correct?

<p>Under illumination, concentration of Ca ions decreases in a photoreceptor (C)</p> Signup and view all the answers

A person has unilateral hearing loss. Based only on this limited amount of information, which of the following statements best indicates a likely site of lesion?

<p>Acoustic division of the eighth cranial nerve (A)</p> Signup and view all the answers

Which nucleus is damaged in Alzheimer's disease that projects cholinergic fibers to the cerebral cortex?

<p>nucleus of Meynert (D)</p> Signup and view all the answers

Delta wave activity in the electroencephalogram:

Refers to low frequency waves of very low amplitude Indicates that the patient is thinking deeply In the waking state is commoner in adults than in children On the left side (when there is alpha activity on the right side) suggests a left-sided brain abnormality

<p>4 is correct (B)</p> Signup and view all the answers

Olfactory impulses are relayed directly to the cerebral cortex by the:

<p>lateral olfactory stria (C)</p> Signup and view all the answers

A 39-year-old handball hustler reported that every time he looked at a court where he had lost a match in the finals of a tournament the previous year, his blood pressure went up. The most important neural link underlying this reaction was a projection from the "----------" to the "-------"*

<p>Amygdala, hypothalamus</p> Signup and view all the answers

What is true about the eye?

The pressure within the eye (the intraocular pressure) is about 15 mmHg The pupils constrict when the eye is focused on a near object. When light is shone in one eye, both pupils constrict. The diameter of the pupils is controlled exclusively by the sympathetic innervation.

<p>1 and 3 are correct (C)</p> Signup and view all the answers

Cortical area receiving input from the medial geniculate body is:

<p>primary auditory cortex (C)</p> Signup and view all the answers

Which of the following compounds are necessary for NO biosynthesis?

<p>L-arginine (C), Molecular oxygen (@), Reduced nicotinamide adenine dinucleotide phosphate (@)</p> Signup and view all the answers

The utricle: contains endolymph contains gravity receptors contains calcified granules can initiate reflex changes in muscle tone

<p>all are correct (A)</p> Signup and view all the answers

A patient with the inability to recognize the source of sounds may be expected to have damage to which of the following nuclei?

<p>Superior olivary (A)</p> Signup and view all the answers

Which statement about eye is correct?

<p>the blind spot produced by the optic disc is medial to the visual axis (B)</p> Signup and view all the answers

Match the connections in the column on the left with the thalamic nuclei in the column on the right; a given thalamic nucleus may be used more than once or not at all.

<p>Input from the medial lemniscus = Ventral posterolateral nucleus (VPL) Inputs from the mammillothalamic tract = Anterior nucleus Outputs to the superior temporal gyrus = Medial geniculate nucleus (MGN)</p> Signup and view all the answers

Match the connections in the column on the left with the thalamic nuclei in the column on the right; a given thalamic nucleus may be used more than once or not at all.

<p>Outputs to the postcentral gyrus = Ventral posteromedial nucleus (VPM) Outputs to the precentral gyrus = Ventral lateral nucleus (VL) Outputs to the postcentral gyrus = Ventral posterolateral nucleus (VPL) Outputs to the occipital lobe = Lateral geniculate nucleus</p> Signup and view all the answers

If the focal length of the lens is 20 cm, the power of the lens is:

<p>5 D (D)</p> Signup and view all the answers

Which of the following structures is NOT involved with the sensation of taste?

<p>ventral posterolateral nucleus of thalamus (B)</p> Signup and view all the answers

Which of the statements are correct describing phenomenon of neuroinflamation?

<p>Excessive production of reactive oxygen species may occur during neuroinflammation (B), Microglial cells are involved in neuroinflammatory response in the brain (D)</p> Signup and view all the answers

Aphasia:

Causes loss of speech without paralysis of the speech muscles Usually results from right-sided cortical damage Is motor if a patient understands words but lacks the skills to express them Is sensory if caused by impairment of hearing

<p>1 and 3 are correct (D)</p> Signup and view all the answers

Neurons projecting directly to cerebral cortex without thalamic relay include:

<p>all are correct (D)</p> Signup and view all the answers

Endolymph:

Is found in the scala media Has a potassium concentration close to that of intracellular fluid Bathes the cilia of the hair cells of the inner ear Is electrically positive with respect to perilymph

<p>all are correct (D)</p> Signup and view all the answers

Match the type of damage in the visual pathway to its corresponding visual field defect:

<p>Damage to optic tract = Contralateral homonymous hemianopia Damage to Meyer's loop = Contralateral superior quadrantanopia Damage to the center of the optic chiasm = Bitemporal hemianopia</p> Signup and view all the answers

Please match the nuclei of the amygdala with their respective roles:

<p>Basolateral nuclei = Attaching emotional significance to stimulus Corticomedial nuclei = Emotional affective response to smell and food Central nucleus = Regulation of visceral responses to stimuli</p> Signup and view all the answers

Bilateral loss of hippocampus results in

<p>Anterograde amnesia (A)</p> Signup and view all the answers

Fornix connects hippocampus to

<p>Mamillary body (A)</p> Signup and view all the answers

Hippocampal formation includes

<p>Dentate gyrus (A), Hippocampus proper (D), Subiculum (@)</p> Signup and view all the answers

Limbic system includes

<p>Cingulate gyrus (A), Hippocampal formation (B), Amygdala (@)</p> Signup and view all the answers

The red arrow indicates:

<p>Subiculum (D)</p> Signup and view all the answers

Stria terminalis originates at:

<p>Amygdala (@)</p> Signup and view all the answers

Which of these structures is (are) included in limbic lobe?

<p>Cingulate gyrus (B), Parahippocampal gyrus (D)</p> Signup and view all the answers

Which of the nuclei of thalamus is (are) part of limbic system?

<p>Anterior nuclei (A)</p> Signup and view all the answers

Which representation of the visual fields corresponds to a lesion at E?

<p>C (@)</p> Signup and view all the answers

What statement (statements) is (are) correct about detachment of the retina?

<p>Neural retina separates from the pigmental epithelium (A), Nutrients from the choroid capillaries cannot reach photosensory cells (@)</p> Signup and view all the answers

Paradoxical (rem) sleep

Is the first state of sleep entered when a person falls asleep Occurs only once during the night while other sleep stages occur several times Is associated with a cortical EEG pattern of delta (1-4hz) range activity Is characterized by rapid eye movements

<p>4 (C)</p> Signup and view all the answers

Small firm nodule was excised in the left hand during surgical procedure. Conclusion of pathology report: schwannoma. Most likely morphologic features visible by light microscopy in this case:

<p>hypo - and hypercellular areas in same neoplasm (D)</p> Signup and view all the answers

Which statements about the auditory system are true?

The normal range of audible frequencies for humans is from 20hz to 50000hz (50kHz) For normal speech we need to hear approximately from 300Hz to 4kHz There is a linear relationship between increase in sound pressure and the perceived increase in loudness A time delay between the arrival of a sound at each ear is one way in which the direction of a sound can be localized

<p>2 and 4 are correct (@)</p> Signup and view all the answers

Which statement (s) about macule of the utricle is (are) correct?

<p>contain sensory cells with many stereocilia and one kinocilium (B), the macula of the utricle is oriented at right angle to that of the saccule (C), sensory cells have glucoprotein coating secreted by supporting cells (@), sensory cells provide information about increase or decrease of the velocity of the movement (acceleration and deceleration) (@)</p> Signup and view all the answers

Which statement (s) about amacrine cells of the retina is (are) correct?

<p>amacrine cells connect bipolar cells with several ganglionic cells (B), amacrine cells (their cell bodies) are located in the inner nuclear layer of the retina (C)</p> Signup and view all the answers

An MRI of head area was performed for a 56 year old female, and a tumor mass was identified in the left frontal cerebral lobe. Most likely, morphologic feature(-s) of cerebral neoplasm observed in the image is/are:

<p>increased mitotic rate (B), focal necrosis (D)</p> Signup and view all the answers

Bilateral damage to which cortical region can result in color agnosia?

<p>V4 (D)</p> Signup and view all the answers

Occlusion of which artery would most severely comprise the blood supply to the visual cortex

<p>posterior cerebral (D)</p> Signup and view all the answers

Which nerve innervates teeth?

<p>trigeminal (B)</p> Signup and view all the answers

Fibers from this structure travel in the radiatio optica (meyer loop) before synapsing in the occipital lobe

<p>lateral geniculate nucleus (A)</p> Signup and view all the answers

Taste:

From the anterior of the tongue is transmitted via the chorda tympani For bitterness is transduced through a second messenger system For sourness (acid) is transduced by direct blockade of apical k+ channels on the receptor cells For saltiness is mainly located at the back of the tongue

<p>1, 2, 3 (C)</p> Signup and view all the answers

19-year old college student is a member of the schools hockey team. During a recent game he had been hit forcefully in the right eye by an opponent's stick. Fortunately, no bones were fractured. Soon after the incident, he began to experience double vision (diplopia) when looking to his right. Which of the following nerves is MOST likely damaged?

<p>Abducens (D)</p> Signup and view all the answers

Although 72-year old women was unconcerned herself, her daughters inspired mother examination, because her personality was changing drastically. For example, she now laughed inappropriately and seemed utterly unconcerned with things that had previously interested her. After examination neurologist suspected tumor. If the patient does have a tumor, which part of the brain is most likely being compressed by the tumor?

<p>Frontal lobe (D)</p> Signup and view all the answers

By which feature the receptive fields of the simple cortical cells differ from those of LGN?

<p>Orientation selectivity (D)</p> Signup and view all the answers

When light is directed into one eye, the pupil:

<p>Does not respond if cholinergic effects are blocked (D)</p> Signup and view all the answers

Match the following responses to the location where the signal of light and activation of rhodopsin induce effects:

<p>In the ganglion cells = firing of action potential In the bipolar cells = depolarization In the photoreceptors = hyperpolarization</p> Signup and view all the answers

Identify the region indicated by the red circle

<p>optic disc (C)</p> Signup and view all the answers

What supporting cells are located in the retina?

<p>astrocytes (A), microglia (B), muller cells (C)</p> Signup and view all the answers

What cells are indicated by the arrows

<p>ganglion cells (B)</p> Signup and view all the answers

What statement (statements) is (are) characteristic for taste buds:

<p>a single taste bud contains 50-100 taste cells that represent all 5 taste sensations (A), taste cell's receptors are located on its apical surface (D)</p> Signup and view all the answers

Adaptation of the eyes for vision in poor light

<p>is partly due to dilatation of the pupil (B), is better for more peripheral than for foveal vision (D)</p> Signup and view all the answers

Identify the structures pointed by the arrows

<p>bowman's (olfactory) glands (@)</p> Signup and view all the answers

What is characteristic for olfactory sensory cells?

<p>they are bipolar neurons (C), they are renewed after 60 days of functioning (@)</p> Signup and view all the answers

This structure has connections with the reticular system and plays an important role in cortical activation:

<p>intralaminar nuclei (B)</p> Signup and view all the answers

Learning and memory:

<p>For long term potentiation induction glutamate NMDA receptors have to pass calcium ions (B), Hippocampus returns information to association cortex for long term memory storage (D)</p> Signup and view all the answers

Which one of the following statements about photopigment is correct?

<p>Photopigment is a complex protein with 11-cis retinal as a component (A)</p> Signup and view all the answers

What statement about ear is correct?

<p>bipolar neurons in the spiral ganglion have a peripheral process which end on hair cells, and central process which are components of the cochlear nerve (B)</p> Signup and view all the answers

What statement (statements) is (are) correct about aqueous humor of the eye?

<p>it is secreted by the ciliary epithelium (D), it fills posterior and anterior chambers of the eye (@)</p> Signup and view all the answers

The basilar membrane of the cochlea

<p>vibrates with the same frequency as the applied sound (C), vibrates more strongly the louder the sound (B), is broader at the apex of the cochlea than at the base (A)</p> Signup and view all the answers

Structure C is:

<p>amygdala (D)</p> Signup and view all the answers

The cochlea is sectioned at its first spiral turn and the spiral organ of Corti is revealed at high magnification. Identify the space indicated by the asterisk

<p>tunnel of Corti (C)</p> Signup and view all the answers

What statement(s) is (are) correct about canal of Schlemm

<p>glaucoma develops due to obstruction of Schlemm canal (D), structure is similar to lymphatic vessels, basal lamina is discontinuous (@), it drains aqueous humor from anterior chamber of the eye to episcleral veins (@)</p> Signup and view all the answers

Tympanic membrane has a contact with:

<p>malleus (D)</p> Signup and view all the answers

A patient complains of difficulty seeing in dim light or at night. The impaired "----------" I adaptation of retina indicates the malfunction of "-------" and so called "----------". It is a result of "---------" "----------" as it is required for the regeneration of rhodopsin

<p>A patient complains of difficulty seeing in dim light or at night. The impaired &quot;dark&quot; I adaptation of retina indicates the malfunction of &quot;rods&quot; and so called &quot;night blindness&quot;. It is a result of &quot;retinol&quot; &quot;deficiency&quot; as it is required for the regeneration of rhodopsin</p> Signup and view all the answers

Identify the structure noted by the green asterisk

<p>It is a spiral ganglion; it contains bipolar neurons which axons are going to the cochlear nuclei of the brain (@)</p> Signup and view all the answers

Tile otolith organs are responsible for

  1. producing the vestibular-ocular reflex
  2. producing rotatory nystagmus
  3. detecting angular acceleration
  4. detecting the posttion oi the head in space

<p>4 (D)</p> Signup and view all the answers

The region indicated with oval dashed line is "-------" and area indicated by the green asterisk is very important because here we may find "-------------"

<p>The region indicated with oval dashed line is &quot;optic disc&quot; and area indicated by the green asterisk is very important because here we may find &quot;Axons of retinal ganglion cells&quot;</p> Signup and view all the answers

Which statement(s) regarding embryological development of the eye is(are) correct?

<p>optic cup develops from the optic vesicle (A), retina of the eye develops from inner layer of the optic cup (C)</p> Signup and view all the answers

Cerebral area concerned with spatial concepts, recognition of faces, music, and pictographic language

<p>nondominant hemisphere (B)</p> Signup and view all the answers

Which stablemen's about the auditory system are true?

  1. The tympanic membranes tend to bulge inwards during descent in an airplane who~ cabin is not pressurized
  2. The tympanic membrane has an area smaller than that of the oval window
  3. Vibrations of the oval window exert more force per unit area than tile tympanic membrane vibrations
  4. Sound waves sound twice as loud when !heir intensity is doubled

<p>1 and 3 are correct (A)</p> Signup and view all the answers

Most of the fibers in the anterior commissure interconnect the:

<p>temporal lobes (D)</p> Signup and view all the answers

Analgesia produced by brain stimulation is mediated by:

  1. neurons of tile periaqueductal gray matter in tile midbrain
  2. raphe neurons
  3. opiate receptors
  4. enkephalins

<p>all are correct (A)</p> Signup and view all the answers

Which of the following is the most likely cause inability to speak in a patient suffering from a stroke?

<p>occlusion of the left middle cerebral artery, resulting in damage to the portion of the frontal lobe (B)</p> Signup and view all the answers

Select, which of the following features differ comparing photoreceptors of retina- rods and cones.

<p>Visual acuity (C), Photopigment (D)</p> Signup and view all the answers

When the cochlea is sectioned at its first spiral turn and the spiral organ of Corti is revealed at high magnification, which structure is indicated by the arrow?

<p>tectorial membrane (@)</p> Signup and view all the answers

Learning and memory

  1. Habituation is due to reduction of sensory signal
  2. Long term potentiation lasts longer than half an hour
  3. Declarative memory is saved in motor cortical areas
  4. Long term potentiation requires strong influx of calcium ions

<p>2 and 4 are correct (A)</p> Signup and view all the answers

A 65-year-old man presents with persistent headaches and gradual visual field loss in his fight eye. Ophthalmic examination demonstrates high intraocular pressure. The patient is subsequently diagnosed with closed-angle glaucoma, caused by inadequate drainage of aqueous humor. Which of the following produce the aqueous humor of the eye?

<p>Non-pigmented epithelial cells of the ciliary processes (@)</p> Signup and view all the answers

Outer wall of the cochlear duct is made of:

<p>Stria vascularis that secretes perilymph (A)</p> Signup and view all the answers

In an individual with myopia:

<p>the eye tends to be longer than average from cornea to retina (D)</p> Signup and view all the answers

What structures are indicated by the labels in this picture?

<p>1- cornea epithelium, 2 - Bowman's membrane, 3 - corneal stroma, 4 - posterior basement membrane, 5 - corneal endothelium (A)</p> Signup and view all the answers

30 years old male patient was diagnosed with von Hippel - Lindau disease. Most likely the diagnosed disease of this patient may have manifested with:

<p>spinal cord hemangioblastoma (A), mediastinal paraganglioma (@)</p> Signup and view all the answers

Which statements about amacrine cells of the retina is (are) correct?

<p>Amacrine cells connect bipolar cells with several ganglionic cells (B), Amacrine cells (their cell bodies) are located in the inner nuclear layer of the retina (C)</p> Signup and view all the answers

Photoreceptors:

<p>contain pigments which are broken dawn, or bleached, by light (A), in the fovea are all cones (C)</p> Signup and view all the answers

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