Unveiling the Secrets of T Cell Anergy
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Questions and Answers

Which of the following is the main reason for the induction of anergy in T cells?

  • Recognition of self antigens with high levels of costimulators
  • Recognition of non-self antigens without costimulation
  • Recognition of self antigens without costimulation (correct)
  • Recognition of non-self antigens with high levels of costimulators
  • Which receptors are involved in inhibiting T cell responses during anergy induction?

  • CD152 and APC
  • CD28 and PD-1 (correct)
  • TCR and CTLA-4
  • CD28 and CD279
  • What happens to T cell receptors when T cells recognize self antigens without costimulation?

  • They become more sensitive to antigen recognition
  • They become resistant to inhibitory signals
  • They lose their ability to transmit activating signals (correct)
  • They undergo intracellular destruction
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