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Questions and Answers
Which of the following is the main reason for the induction of anergy in T cells?
Which of the following is the main reason for the induction of anergy in T cells?
- Recognition of self antigens with high levels of costimulators
- Recognition of non-self antigens without costimulation
- Recognition of self antigens without costimulation (correct)
- Recognition of non-self antigens with high levels of costimulators
Which receptors are involved in inhibiting T cell responses during anergy induction?
Which receptors are involved in inhibiting T cell responses during anergy induction?
- CD152 and APC
- CD28 and PD-1 (correct)
- TCR and CTLA-4
- CD28 and CD279
What happens to T cell receptors when T cells recognize self antigens without costimulation?
What happens to T cell receptors when T cells recognize self antigens without costimulation?
- They become more sensitive to antigen recognition
- They become resistant to inhibitory signals
- They lose their ability to transmit activating signals (correct)
- They undergo intracellular destruction
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