Podcast
Questions and Answers
Which process produces siRNAs that silence complementary sequences?
Which process produces siRNAs that silence complementary sequences?
- RNA Interference (correct)
- Gene disruption/knockout
- Synthetic siRNAs
- microRNA (miRNA)
What is the main function of synthetic siRNAs?
What is the main function of synthetic siRNAs?
- To protect the germline from transposable elements
- To introduce mutated genes to embryonic stem cells
- To produce a transient outcome by targeting mRNA (correct)
- To block post-transcriptional expression of genes
Which method of vaccine production involves making recombinant gene to produce recombinant protein as vaccine?
Which method of vaccine production involves making recombinant gene to produce recombinant protein as vaccine?
- Traditional method (correct)
- Kariko & Weissman method
- Bivalent vaccines
- mRNA vaccines
What is the role of microRNA (miRNA) in gene expression?
What is the role of microRNA (miRNA) in gene expression?
Which scientists discovered that base-modified mRNA can be used to block activation of inflammatory reactions?
Which scientists discovered that base-modified mRNA can be used to block activation of inflammatory reactions?
What is the precursor of siRNA that forms a hairpin loop?
What is the precursor of siRNA that forms a hairpin loop?
Which of the following is an advantage of using lipid nanoparticles for delivering mRNA vaccines?
Which of the following is an advantage of using lipid nanoparticles for delivering mRNA vaccines?
What is the main function of PIWI-interacting RNA (piRNA)?
What is the main function of PIWI-interacting RNA (piRNA)?
Which companies used lipid nanoparticles with PEG in their mRNA vaccines?
Which companies used lipid nanoparticles with PEG in their mRNA vaccines?
What enzyme complex binds to siRNA and attaches to the guide strand?
What enzyme complex binds to siRNA and attaches to the guide strand?
What is a limitation of mRNA vaccines?
What is a limitation of mRNA vaccines?
What enzyme is part of the RISC and cleaves and degrades mRNA?
What enzyme is part of the RISC and cleaves and degrades mRNA?
Which organisms are commonly used as eukaryotic model organisms for genome editing?
Which organisms are commonly used as eukaryotic model organisms for genome editing?
What is the function of Dicer in RNA interference?
What is the function of Dicer in RNA interference?
What is the classic way of genome editing that involves changing DNA at a desired position using a PCR-based technique?
What is the classic way of genome editing that involves changing DNA at a desired position using a PCR-based technique?
Which type of RNA contains the genetic information for protein translation?
Which type of RNA contains the genetic information for protein translation?
What is the purpose of cassette mutagenesis in genome editing?
What is the purpose of cassette mutagenesis in genome editing?
What is the limitation of synthetic siRNAs as a treatment?
What is the limitation of synthetic siRNAs as a treatment?
What is the difference between random and targeted insertion in genome editing using viral vectors?
What is the difference between random and targeted insertion in genome editing using viral vectors?
What is the purpose of knockout mice in genome editing?
What is the purpose of knockout mice in genome editing?