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Questions and Answers
Arrange the following cellular events in the proper order in
which they occur in the activation of NFkB pathway
1= IKK complexes phosphorylate IκB proteins
2= IκB ubiquitination and proteasomal degradation
3= NF-κB complexes translocate into the nucleus
4= NF-κB complexes induce target gene expression
Arrange the following cellular events in the proper order in which they occur in the activation of NFkB pathway 1= IKK complexes phosphorylate IκB proteins 2= IκB ubiquitination and proteasomal degradation 3= NF-κB complexes translocate into the nucleus 4= NF-κB complexes induce target gene expression
How does NF-κB induce gene expression?
How does NF-κB induce gene expression?
Activation of NFkB pathway results in the transcription of
genes involved in cell survival and inflammation. What
prevents this process from occurring in the absence of
stimuli?
Activation of NFkB pathway results in the transcription of genes involved in cell survival and inflammation. What prevents this process from occurring in the absence of stimuli?
Ubiquitination is a post-translational modification process, that
attaches ubiquitin to a target protein. This process plays an
important role in the activation of NFkB pathway. What is
ubiquitin?
Ubiquitination is a post-translational modification process, that attaches ubiquitin to a target protein. This process plays an important role in the activation of NFkB pathway. What is ubiquitin?
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