term 1 -week 7
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Questions and Answers

Which of the following is NOT true about glucagon?

  • It is produced in the alpha cells of the pancreas
  • It inhibits glycogenolysis (correct)
  • It is released in response to low blood glucose level ( hypoglycaemia)
  • It is a peptide hormon

In a G protein coupled receptor (GPCR):

  • The G protein alpha subunit is activated by binding with GTP (correct)
  • ) The G protein alpha subunit is activated by binding with GDP
  • The G protein is activated by binding of insulin to its receptor
  • The G protein receptor is only found in liver cells

cAMP is crucial for regulating the action of epinephrine because:

  • ) It activates protein kinase A (PKA) (correct)
  • ) it inactivates PKA
  • cAMP is not required for the action of epinephrine
  • ) cAMP is removed by epinephrine

Which out of the following statements is true about Gprotein coupled receptors?

<p>The N-terminal chain is extracellular and C-terminal chain is intracellular (A)</p> Signup and view all the answers

Protein kinase A is _________

<p>Allosterically activated by cyclic AMP (C)</p> Signup and view all the answers

Which of the following catalyses the cutting of PIP2 into IP3 and diacylglycerol in cell signalling?

<p>) Phospholipase C (B)</p> Signup and view all the answers

A hormone can be considered as ___________

<p>First messenger (A)</p> Signup and view all the answers

. Which second messenger signals the release of Ca+2 from endoplasmic reticulum?

<p>IP3 (A)</p> Signup and view all the answers

. Glycogen phosphorylase kinase has its activity increased by

<p>b/c (D)</p> Signup and view all the answers

How does epinephrine release glucose so quickly?

<p>Enzyme cascades magnify its effect (D)</p> Signup and view all the answers

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