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Questions and Answers
What is the primary purpose of vaccinating newborns against tuberculosis in the first week of life?
To prevent the development of severe forms of tuberculosis
What is the key genetic difference between the M. Bovis (BCG) vaccine strain and virulent MBT strains?
The M. Bovis (BCG) vaccine strain lacks a fragment of the RD1 genome that encodes the secretion of CFP10 and ESAT6 proteins
What is the duration of specific immunity against tuberculosis following vaccination with the BCG vaccine?
Up to 7 years of age
What proteins are encoded by the RD1 genome fragment that are involved in the virulent properties of MBT strains?
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What is the age range during which newborns are vaccinated against tuberculosis in this country?
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What is the significance of the RD1 genome fragment in determining the virulent properties of MBT strains?
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Why is the M.Bovis (BCG) vaccine strain used for vaccination against tuberculosis?
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What is the role of CFP10 and ESAT6 proteins in the pathogenesis of tuberculosis?
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How does the M.Bovis (BCG) vaccine strain contribute to the development of long-term immunity against tuberculosis?
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What is the significance of vaccinating newborns against tuberculosis in the first week of life?
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Study Notes
Formation of Anti-Tuberculosis Immunity
- Newborns are vaccinated against tuberculosis on days 3-7 of life in our country to prevent severe forms of the disease.
- The vaccine contains live strains of M.Bovis (BCG).
- The M.Bovis (BCG) vaccine strain lacks the RD1 genome fragment, which encodes the secretion of CFP10 and ESAT6 proteins.
- CFP10 and ESAT6 proteins determine the main virulent properties of the tuberculosis pathogen.
- As a result of vaccination, a long-term specific immunity against tuberculosis is formed.
- This immunity lasts up to 7 years of age, either under or over.
Formation of Anti-Tuberculosis Immunity
- Newborns are vaccinated against tuberculosis on days 3-7 of life in our country to prevent severe forms of the disease.
- The vaccine contains live strains of M.Bovis (BCG).
- The M.Bovis (BCG) vaccine strain lacks the RD1 genome fragment, which encodes the secretion of CFP10 and ESAT6 proteins.
- CFP10 and ESAT6 proteins determine the main virulent properties of the tuberculosis pathogen.
- As a result of vaccination, a long-term specific immunity against tuberculosis is formed.
- This immunity lasts up to 7 years of age, either under or over.
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Description
This quiz covers the formation of anti-tuberculosis immunity, specifically the vaccination process in newborns and the role of the BCG vaccine strain in preventing severe forms of the disease. It also explores the proteins involved in determining the virulent properties of the tuberculosis pathogen.
