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组织分布的HLA系统复杂性

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Questions and Answers

HLA-B*5801基因在台灣人口中的檢出率約為多少？

15-20% (correct)

5-10%

10-15%

20-25%

HLA-A基因共有多少種不同的sero-types？

237

21 (correct)

SJS/TEN在台灣每年每百萬人口的發生率是多少？

2-3例

6-7例

8例 (correct)

4-5例

HLA system中DR類別有多少個不同的alleles？

368 Signup and view all the answers

PCR-SSP (PCR with sequence specific primers) 的第一步是什麼？

加入taq和DNA到Dmix Signup and view all the answers

脊髓性肌肉萎縮症(SMA)的遺傳模式為下列何者？

自體染色體隐性遗传模式 Signup and view all the answers

SMN1和SMN2基因之间的主要区别在于哪个部分？

exon 7 Signup and view all the answers

以下哪种基因檢测方法被認定為脊髓性肌肉萎縮症(SMA)的標準方法？

MLPA Signup and view all the answers

利用MLPA进行SMA基因检测的主要局限性是什么？

SMN1基因位于同一染色体上 Signup and view all the answers

哪种治疗脊髓性肌肉萎缩症(SMA)的药物需要进行脊髓内注射？

Nusinersen髓鞘内给药 Signup and view all the answers