Stomach Mucosa and Gastric Glands
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Questions and Answers

What type of epithelium lines the mucosa of the stomach?

  • Pseudostratified epithelium
  • Simple cuboidal epithelium
  • Simple columnar epithelium (correct)
  • Stratified squamous epithelium
  • What is the function of chief cells in the gastric fundic glands?

  • Producing pepsin for protein digestion (correct)
  • Regenerating damaged cells
  • Secreting hydrochloric acid
  • Regulating blood flow and smooth muscle movement
  • What is the primary function of the mucosa in the stomach?

  • Producing digestive enzymes
  • Protecting the stomach wall from acid and enzymes (correct)
  • Regulating blood flow and smooth muscle movement
  • Absorbing nutrients from food
  • What type of cells are responsible for secreting hydrochloric acid in the stomach?

    <p>Parietal cells (C)</p> Signup and view all the answers

    What is the name of the plexus of nerves found in the submucosa of the stomach?

    <p>Meissner's plexus (A)</p> Signup and view all the answers

    What is the function of the muscularis mucosa in the stomach?

    <p>Coordinating the movement of the mucosa (C)</p> Signup and view all the answers

    What type of muscle is found in the muscularis externa of the stomach?

    <p>Smooth muscle (A)</p> Signup and view all the answers

    What is the outermost layer of the stomach wall?

    <p>Serosa (A)</p> Signup and view all the answers

    What is the function of the mucosa in the small intestine?

    <p>To absorb nutrients from food (B)</p> Signup and view all the answers

    What is the function of the pylorus gland?

    <p>To secrete intrinsic factor for vitamin B12 absorption (B)</p> Signup and view all the answers

    What is the purpose of the villi in the small intestine?

    <p>To increase the surface area for absorption (D)</p> Signup and view all the answers

    What is the function of the muscularis in the small intestine?

    <p>To perform peristaltic contractions (A)</p> Signup and view all the answers

    What is the function of the fundic gland?

    <p>To secrete hydrochloric acid and pepsin for digestion (C)</p> Signup and view all the answers

    What is the function of the Brunner's glands in the small intestine?

    <p>To produce alkaline mucus to protect the duodenum (B)</p> Signup and view all the answers

    What is the function of the goblet cells in the small intestine?

    <p>To secrete mucus for lubrication (B)</p> Signup and view all the answers

    What is the length of the small intestine?

    <p>6 meters (D)</p> Signup and view all the answers

    What is the primary function of the large intestine?

    <p>Absorption of water and storage of fecal matter (C)</p> Signup and view all the answers

    Which type of cell is responsible for secreting anti-bacterial lysozymes in the small intestine?

    <p>Paneth cells (C)</p> Signup and view all the answers

    What is the characteristic of the mucosa in the large intestine?

    <p>Simple columnar absorptive cells with many goblet cells (A)</p> Signup and view all the answers

    What is the location of the intestinal renewal stem cells in the small intestine?

    <p>In the base of the crypt (C)</p> Signup and view all the answers

    What is the function of the M-cells in the small intestine?

    <p>Antigen transport from the gut lumen (A)</p> Signup and view all the answers

    What is the characteristic of the muscularis externa in the large intestine?

    <p>Three separate longitudinal ribbons of smooth muscle (C)</p> Signup and view all the answers

    What is the name of the skeletal voluntary muscles located between the outer and inner lips?

    <p>Orbicularis oris (D)</p> Signup and view all the answers

    What type of epithelium covers the Red Margin of the lip?

    <p>Partially keratinized stratified squamous (B)</p> Signup and view all the answers

    What is the function of the tongue during mastication and swallowing?

    <p>To mix food with saliva and aid in swallowing (B)</p> Signup and view all the answers

    What is the characteristic of the dorsal surface of the tongue?

    <p>It is rough and partially keratinized (C)</p> Signup and view all the answers

    What is the function of the Labial muco-serous glands found in the inner surface of the lip?

    <p>Produce saliva (D)</p> Signup and view all the answers

    What is the structure that comes into contact with the Red Margin of the lip?

    <p>Tongue (B)</p> Signup and view all the answers

    What type of papillae are present on the edge of the tongue?

    <p>Fungiform papillae (D)</p> Signup and view all the answers

    What is the type of skin found on the outer surface of the lip?

    <p>Thin hairy skin (A)</p> Signup and view all the answers

    What is the function of Von Ebner glands?

    <p>To facilitate taste sensation and wash away food particles (D)</p> Signup and view all the answers

    What is the layer of tissue found under the epithelium of the inner surface of the lip?

    <p>Connective tissue (D)</p> Signup and view all the answers

    What is the characteristic of the ventral surface of the tongue?

    <p>It is smooth and non-keratinized (C)</p> Signup and view all the answers

    What is the purpose of the lingual papillae?

    <p>To facilitate taste sensation (A)</p> Signup and view all the answers

    How many vallate papillae are present on the dorsal surface of the tongue?

    <p>8-12 (B)</p> Signup and view all the answers

    What is the color of the fungiform papillae?

    <p>Reddish (B)</p> Signup and view all the answers

    What is the shape of the filiform papillae on the tongue?

    <p>Conical (A)</p> Signup and view all the answers

    What is the function of the supporting cells in the taste buds?

    <p>They act as bodyguards for the taste buds. (A)</p> Signup and view all the answers

    What is the name of the place where food enters the taste buds?

    <p>Taste pore (B)</p> Signup and view all the answers

    What type of epithelium is found in the lips and tongue?

    <p>Non-keratinizing stratified squamous epithelium (D)</p> Signup and view all the answers

    What is the function of the basal cells in the taste buds?

    <p>They act as stem cells for renewal of other cells. (A)</p> Signup and view all the answers

    What is the shape of the fungiform papillae on the tongue?

    <p>Fungiform (C)</p> Signup and view all the answers

    What is the function of the cardiac glands in the mucosa of the esophagus?

    <p>They produce alkaline secretions to neutralize acid. (B)</p> Signup and view all the answers

    How many layers are present in the wall of the esophagus?

    <p>4 (B)</p> Signup and view all the answers

    Flashcards

    Stomach Mucosa

    The lining of the stomach, composed of simple columnar epithelium and containing branched tubular gastric glands.

    Mucous Surface Cells

    Specialized cells found in the gastric glands that secrete mucus to protect the stomach lining from acidic gastric juice.

    Chief Cells

    Cells in the gastric glands that produce pepsin, an enzyme essential for protein digestion.

    Parietal Cells

    Cells in the gastric glands that secrete hydrochloric acid (HCl) and intrinsic factor, crucial for vitamin B12 absorption.

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    Gastric Enteroendocrin Cells

    These cells in gastric glands regulate blood flow and muscle movement in the stomach.

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    Stem Cells

    Found in the stomach lining, they constantly replace damaged cells, ensuring the stomach's integrity.

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    Serosa

    The outermost layer of the stomach wall, providing protection and support. It is made up of connective tissue and blood vessels.

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    Muscularis Externa

    A layer of smooth muscle in the stomach wall responsible for churning food and propelling it towards the small intestine.

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    Auerbach's Plexus

    Located in the stomach wall, it contains nerves that control muscle contractions and help regulate digestion.

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    Submucosa

    A layer of connective tissue beneath the mucosa, containing nerves, blood vessels, and lymphatic system.

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    Meissner's Plexus

    Located in the submucosa, they control smooth muscle contractions and regulate digestive processes.

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    Mucosa

    The innermost layer of the stomach wall, composed of epithelium, lamina propria, and muscularis mucosa.

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    Pylorus

    A muscular valve that controls the passage of food from the stomach to the small intestine.

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    Pylorus Gland

    Specialized glands located in the pyloric region of the stomach, secreting mucus and contributing to digestion.

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    Mixing of Food in the Stomach

    The process of mixing and churning food in the stomach with gastric juice.

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    Gastric Juice

    A mixture of hydrochloric acid, enzymes, and mucus secreted by the stomach lining.

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    Pepsin

    A protein-digesting enzyme produced by chief cells in the stomach.

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    Intrinsic Factor

    A key component of gastric juice that helps in the absorption of vitamin B12.

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    Small Intestine

    The long, coiled tube that follows the stomach, responsible for most nutrient absorption.

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    Villi

    Finger-like projections in the small intestine that increase the surface area for nutrient absorption.

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    Crypts

    Small depressions in the lining of the small intestine that contain glands secreting digestive enzymes.

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    Goblet Cells

    Specialized cells in the small intestine that produce mucus, lubricating food and aiding in its passage.

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    Paneth Cells

    Cells in the small intestine that secrete antibacterial agents like lysozyme.

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    Intestinal Renewal Stem Cells

    These cells, located in the base of the crypts of the small intestine, are responsible for renewing the intestinal lining.

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    Enteroendocrine Cells

    Cells in the small intestine that monitor and regulate digestive function.

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    Large Intestine

    The final section of the digestive tract, where water absorption and waste processing occur.

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    Goblet Cells in Large Intestine

    Cells in the large intestine that produce mucus to soften stool and ease its passage.

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    Appendices Epiploicae

    Structures in the large intestine that contain pockets of fat and serve to absorb water and electrolytes.

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    Appendix

    A small, finger-like projection that extends from the large intestine and plays a role in immunity.

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    Teniae Coli

    A muscular band that runs along the length of the colon, helping to move feces along.

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    Defecation

    The process of eliminating waste from the body.

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    Study Notes

    Stomach Mucosa

    • Lined by simple columnar epithelium and contains branched tubular gastric glands.

    Gastric Gland Cells

    • Simple columnar epithelium: mucous surface secreting and protects the stomach wall from HCL (pH 2.5).
    • Chief cells (zymogen cells): produce pepsin for protein digestion.
    • Parietal (oxyntic) cells: secrete hydrochloric acid and intrinsic factors.
    • Gastric enteroendocrin cells: coordinate blood flow and smooth muscle movement.
    • Stem cells: regenerate damaged cells.

    Stomach Layers

    • Mucosa: consists of three parts - epithelial lining, lamina propria of C.T. with fundic gland, and muscularis mucosa.
    • Submucosa: contains Meissner's plexus of nerves and lymphatics, and fundic glands.
    • Muscularis externa: smooth muscle layer with Auerbach's plexus, responsible for peristaltic contractions.
    • Serosa: peritoneal or C.T. covering.

    Function of Stomach

    • Mixes food with gastric juice (HCL, mucosa protection, pepsin enzyme, and intrinsic factor for vitamin B12 absorption).
    • Absorbs water and electrolytes.

    Pylorus

    • Muscular sphincter.
    • Pylorus gland: contains mucus, stem cells, and enteroendocrin cells.
    • Short, wide gastric pit.

    Small Intestine

    • Function: absorption of food.
    • Length: 6 meters.
    • Mucosa: forms villi, crypts, and simple columnar (absorptive) cells with goblet cells that lubricate food.
    • Submucosa: contains mucous glands (Brunner's glands) and Peyer's patches of lymphatic nodules.
    • Muscularis: smooth muscles with Auerbach's plexus, performs peristaltic contractions.
    • Serosa: simple squamous peritoneum.

    Small Intestine Mucosal Cells

    • Surface simple columnar absorptive cells on villi with microvilli.
    • Goblet cells.
    • Paneth (exocrinocytes) cells: secrete antibacterial lysozymes and tumor necrosis factor.
    • Caveolated cells: present in crypt.
    • M-cells: transporting in crypt.
    • Intestinal renewal stem cells: in base of crypt.
    • Entero-endocrine cells: in crypt.

    Large Intestine

    • Function: absorbs water and stores fecal or residual part during defecation.
    • No villi, only crypts.
    • Mucosa: simple columnar (absorptive) cells with many goblet cells to soften stool.
    • Enteroendocrin and stem cells.
    • Submucosa: Meissner's plexus.
    • Muscularis externa: teniae coli with three separate longitudinal ribbons.
    • Serosa: fat cell appendices epiploicae and appendix.

    The Digestive System

    • The digestive system, also known as the gastrointestinal tract or alimentary canal, consists of the oral cavity, digestive tract, and digestive glands.

    Oral Cavity

    • The oral cavity consists of the lips, tongue, palate, and cheeks.
    • The lips have three histological regions: the outer surface (thin hairy skin), the inner surface (mucous membrane), and the red margin (vermilion).
    • The color of the lip margin can indicate health conditions: pale red (anemia), blue (cyanosis), or red (healthy).

    The Tongue

    • The tongue is a mass of lingual striated muscle covered by mucosa, which helps mix food during mastication and swallowing.
    • The tongue has two surfaces: the dorsal surface (rough, covered by partially keratinized stratified squamous epithelium) and the ventral surface (smooth, covered by non-keratinized stratified squamous epithelium).
    • There are four types of lingual papillae on the tongue:
    • Filiform papillae (most common, with partially keratinized stratified squamous epithelium)
    • Fungiform papillae (reddish in color, with few taste buds)
    • Foliate papillae (on each side of the tongue)
    • Vallate or circumvallate papillae (rich in taste buds, with Von Ebner glands)

    Taste Buds

    • Taste buds are neuro-epithelial organs found on the tongue, containing three layers: receptor taste cells (with microvilli), supporting cells, and basal cells.
    • Taste buds have a taste pore where food enters to be tasted.

    The Esophagus

    • The esophagus is a 25 cm long muscular tube that connects the oral cavity and stomach, conducting food without digesting it.
    • The esophageal wall consists of four layers: mucosa, submucosa, musculosa, and adventitia.
    • The mucosa layer has three sublayers: non-keratinizing stratified squamous epithelium, lamina propria with cardiac glands, and muscularis mucosa.
    • The submucosa layer contains esophageal glands that secrete mucus.
    • The musculosa layer is composed of skeletal muscle in the upper 1/3, mixed in the middle 1/3, and smooth muscle in the lower 1/3.
    • The adventitia layer is connective tissue covering the esophagus with blood vessels and lymphatic vessels.

    The Stomach

    • The stomach is a sac-like, muscular, and extended organ, acting as the first station for digestion.

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