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Questions and Answers
What is the primary mechanism of action of phenytoin?
What is the primary mechanism of action of phenytoin?
- Enhancement of GABA Ion Channels
- Inhibition of Na+ influx
- Stabilization and prolongation of the inactive state (correct)
- Inhibition of Ca2+ influx
Which neurotransmitter is predominantly affected by phenytoin's mechanism of action?
Which neurotransmitter is predominantly affected by phenytoin's mechanism of action?
- Dopamine
- Serotonin
- GABA (correct)
- Glutamate
What is the structural feature that distinguishes phenytoin as a hydantoin?
What is the structural feature that distinguishes phenytoin as a hydantoin?
- 5-membered ring containing 2 nitrogens (correct)
- 7-membered ring containing 3 nitrogens
- 6-membered ring containing 1 nitrogen
- 4-membered ring containing 2 nitrogens
What is the main consequence of inhibiting Na+ influx due to phenytoin usage?
What is the main consequence of inhibiting Na+ influx due to phenytoin usage?
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How does phenytoin affect the generation of action potentials?
How does phenytoin affect the generation of action potentials?
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Which ion channels are primarily targeted by phenytoin's mechanism of action?
Which ion channels are primarily targeted by phenytoin's mechanism of action?
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What is the significance of phenytoin's poor water solubility?
What is the significance of phenytoin's poor water solubility?
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How does phenytoin differ from carbamazepine in terms of mechanism of action?
How does phenytoin differ from carbamazepine in terms of mechanism of action?
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What is the major impact of phenytoin on action potentials in nerve cells?
What is the major impact of phenytoin on action potentials in nerve cells?
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