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Phenytoin Administration and Mechanism of Action Quiz
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Phenytoin Administration and Mechanism of Action Quiz

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@JudiciousSwaneeWhistle

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Questions and Answers

What is the primary mechanism of action of phenytoin?

  • Enhancement of GABA Ion Channels
  • Inhibition of Na+ influx
  • Stabilization and prolongation of the inactive state (correct)
  • Inhibition of Ca2+ influx

    • Which neurotransmitter is predominantly affected by phenytoin's mechanism of action?

  • Dopamine
  • Serotonin
  • GABA (correct)
  • Glutamate

    • What is the structural feature that distinguishes phenytoin as a hydantoin?

  • 5-membered ring containing 2 nitrogens (correct)
  • 7-membered ring containing 3 nitrogens
  • 6-membered ring containing 1 nitrogen
  • 4-membered ring containing 2 nitrogens

    • What is the main consequence of inhibiting Na+ influx due to phenytoin usage?

    <p>Diminished spread of electrical seizure activity</p> Signup and view all the answers

    How does phenytoin affect the generation of action potentials?

    <p>Decreases action potential generation</p> Signup and view all the answers

    Which ion channels are primarily targeted by phenytoin's mechanism of action?

    <p>Na+ channels</p> Signup and view all the answers

    What is the significance of phenytoin's poor water solubility?

    <p>It leads to precipitation in acidic environments</p> Signup and view all the answers

    How does phenytoin differ from carbamazepine in terms of mechanism of action?

    <p>Phenytoin inhibits sodium influx, while carbamazepine enhances GABA neurotransmission</p> Signup and view all the answers

    What is the major impact of phenytoin on action potentials in nerve cells?

    <p>Prolongs the inactive state.</p> Signup and view all the answers

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