Plasmodium malariae, Plasmodium vivax, Plasmodium ovale, and Plasmodium falciparum ʹ The queens and warlords of Plasmodium
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Questions and Answers

What is the Plasmodium species associated with quartan fever cycle?

  • Plasmodium vivax
  • Plasmodium ovale
  • Plasmodium falciparum
  • Plasmodium malariae (correct)
  • Which antimalarial drug blocks Plasmodium heme polymerase?

  • Chloroquine (correct)
  • Quinine
  • Primaquin
  • Mefloquine
  • What is the characteristic of Plasmodium vivax and ovale under microscopy?

  • Irregular-shaped
  • Sickle-shaped
  • Oval-shaped
  • Banana-shaped (correct)
  • Which Plasmodium species is associated with neurologic symptoms due to parasitized RBC occluding the brain, kidney, and lungs?

    <p>Plasmodium falciparum</p> Signup and view all the answers

    What is the drug combination used to treat hypnozoites in the liver, but with caution in G6PD deficiency patients?

    <p>Chloroquine and Primaquin</p> Signup and view all the answers

    What is the purpose of Atovaquone with Proguanil for travelers in the Caribbean?

    <p>Prophylaxis for Caribbean travelers</p> Signup and view all the answers

    What is indicated by the 'buttons' symbol?

    <p>Quartan fever cycle</p> Signup and view all the answers

    Which Plasmodium species is characterized by banana-shaped structures under microscopy?

    <p>Plasmodium ovale</p> Signup and view all the answers

    What is the purpose of Mefloquine?

    <p>Prophylaxis for Caribbean travelers</p> Signup and view all the answers

    Which antimalarial drug is used to treat sickle cell anemia patients?

    <p>Primaquin</p> Signup and view all the answers

    What is the purpose of Atovaquone with Proguanil?

    <p>Prophylaxis for Caribbean travelers</p> Signup and view all the answers

    What is the significance of the 'warlord with shield and axe' symbol?

    <p>Plasmodium vivax and ovale</p> Signup and view all the answers

    Which of the following is associated with an irregular fever pattern?

    <p>Torn shirt</p> Signup and view all the answers

    What is the purpose of Primaquin with Chloroquine?

    <p>To treat hypnozoites in the liver</p> Signup and view all the answers

    Which of the following is used to treat severe malaria infections?

    <p>Artesonate</p> Signup and view all the answers

    What is the purpose of Atovaquone with Proguanil for Caribbean travelers?

    <p>As prophylaxis for travelers</p> Signup and view all the answers

    Which of the following is associated with a bad smelling warlord?

    <p>Plasmodium malariae</p> Signup and view all the answers

    Which of the following is used to treat patients with sickle cell anemia?

    <p>Artemisinins</p> Signup and view all the answers

    Study Notes

    Plasmodium Location and Diagnosis

    • Plasmodium is found in the African wilderness.
    • A blood smear with Giemsa stain is used for diagnosis.

    Plasmodium Species

    • There are four warlords, representing different Plasmodium species.
    • Bad smelling warlord represents Plasmodium malariae.

    Plasmodium Malariae

    • Plasmodium malariae causes quartan fever, with the highest fever on days 1 and 4.

    Plasmodium Vivax and Ovale

    • Warlord with shield and axe represents Plasmodium vivax and ovale.
    • These species produce dormant hypnozoites in the liver.

    Fever Patterns

    • Swinging balls represent the fever cycle, with tertian fever having every other circle on the balls.
    • Torn shirt represents an irregular fever pattern.

    Plasmodium Falciparum

    • False mask represents Plasmodium falciparum.
    • Red headdress, gold chest plate, and belt represent neurologic symptoms, as parasitized RBCs occlude the brain, kidney, and lungs.

    Microscopy

    • Headdress looks like bananas, representing the banana-shaped form of Plasmodium under microscopy.

    Antimalarial Drugs

    • Color queen represents chloroquine, which blocks Plasmodium heme polymerase.
    • Primal queen represents primaquin with chloroquine, used for hypnozoites in the liver, with caution for G6PD deficiency.
    • Me fly queen in palanquin represents mefloquine, used for Caribbean travelers.
    • Top of palanquin with backpacks represents prophylaxis for Caribbean travelers.
    • Ato-vampire queen in palanquin and iguana, with backpacks represents atovoquone with proguanil for travelers in the Caribbean.
    • Artist painting a picture of ato-vampire queen represents artimesians used to treat P.falciparum with atovaquone.
    • Sickle cells in the artist's hand represent the use of these drugs to treat sickle cell anemia patients.
    • IV artesonate represents the treatment for severe malaria infections.
    • Dining queen with tin cans represents quinidine for resistant P.falciparum, which can cause cinchonism.
    • Ivy wrapped around the arm represents IV delivery.

    Life Cycle of Plasmodium

    • Cow with liver spot, mushrooms represents the life cycle of Plasmodium, where Anopholes mosquito carry sporozoites in saliva, which mature to trophozoites in the liver, then divide into merozoites that burst from hepatocyte and infect RBCs.
    • Ring shape represents the immature form of Plasmodium, which has a ring form. Merozoite can also form a gametocyte.

    Plasmodium Location and Diagnosis

    • Plasmodium is found in the African wilderness.
    • A blood smear with Giemsa stain is used for diagnosis.

    Plasmodium Species

    • There are four warlords, representing different Plasmodium species.
    • Bad smelling warlord represents Plasmodium malariae.

    Plasmodium Malariae

    • Plasmodium malariae causes quartan fever, with the highest fever on days 1 and 4.

    Plasmodium Vivax and Ovale

    • Warlord with shield and axe represents Plasmodium vivax and ovale.
    • These species produce dormant hypnozoites in the liver.

    Fever Patterns

    • Swinging balls represent the fever cycle, with tertian fever having every other circle on the balls.
    • Torn shirt represents an irregular fever pattern.

    Plasmodium Falciparum

    • False mask represents Plasmodium falciparum.
    • Red headdress, gold chest plate, and belt represent neurologic symptoms, as parasitized RBCs occlude the brain, kidney, and lungs.

    Microscopy

    • Headdress looks like bananas, representing the banana-shaped form of Plasmodium under microscopy.

    Antimalarial Drugs

    • Color queen represents chloroquine, which blocks Plasmodium heme polymerase.
    • Primal queen represents primaquin with chloroquine, used for hypnozoites in the liver, with caution for G6PD deficiency.
    • Me fly queen in palanquin represents mefloquine, used for Caribbean travelers.
    • Top of palanquin with backpacks represents prophylaxis for Caribbean travelers.
    • Ato-vampire queen in palanquin and iguana, with backpacks represents atovoquone with proguanil for travelers in the Caribbean.
    • Artist painting a picture of ato-vampire queen represents artimesians used to treat P.falciparum with atovaquone.
    • Sickle cells in the artist's hand represent the use of these drugs to treat sickle cell anemia patients.
    • IV artesonate represents the treatment for severe malaria infections.
    • Dining queen with tin cans represents quinidine for resistant P.falciparum, which can cause cinchonism.
    • Ivy wrapped around the arm represents IV delivery.

    Life Cycle of Plasmodium

    • Cow with liver spot, mushrooms represents the life cycle of Plasmodium, where Anopholes mosquito carry sporozoites in saliva, which mature to trophozoites in the liver, then divide into merozoites that burst from hepatocyte and infect RBCs.
    • Ring shape represents the immature form of Plasmodium, which has a ring form. Merozoite can also form a gametocyte.

    Plasmodium Location and Diagnosis

    • Plasmodium is found in the African wilderness.
    • A blood smear with Giemsa stain is used for diagnosis.

    Plasmodium Species

    • There are four warlords, representing different Plasmodium species.
    • Bad smelling warlord represents Plasmodium malariae.

    Plasmodium Malariae

    • Plasmodium malariae causes quartan fever, with the highest fever on days 1 and 4.

    Plasmodium Vivax and Ovale

    • Warlord with shield and axe represents Plasmodium vivax and ovale.
    • These species produce dormant hypnozoites in the liver.

    Fever Patterns

    • Swinging balls represent the fever cycle, with tertian fever having every other circle on the balls.
    • Torn shirt represents an irregular fever pattern.

    Plasmodium Falciparum

    • False mask represents Plasmodium falciparum.
    • Red headdress, gold chest plate, and belt represent neurologic symptoms, as parasitized RBCs occlude the brain, kidney, and lungs.

    Microscopy

    • Headdress looks like bananas, representing the banana-shaped form of Plasmodium under microscopy.

    Antimalarial Drugs

    • Color queen represents chloroquine, which blocks Plasmodium heme polymerase.
    • Primal queen represents primaquin with chloroquine, used for hypnozoites in the liver, with caution for G6PD deficiency.
    • Me fly queen in palanquin represents mefloquine, used for Caribbean travelers.
    • Top of palanquin with backpacks represents prophylaxis for Caribbean travelers.
    • Ato-vampire queen in palanquin and iguana, with backpacks represents atovoquone with proguanil for travelers in the Caribbean.
    • Artist painting a picture of ato-vampire queen represents artimesians used to treat P.falciparum with atovaquone.
    • Sickle cells in the artist's hand represent the use of these drugs to treat sickle cell anemia patients.
    • IV artesonate represents the treatment for severe malaria infections.
    • Dining queen with tin cans represents quinidine for resistant P.falciparum, which can cause cinchonism.
    • Ivy wrapped around the arm represents IV delivery.

    Life Cycle of Plasmodium

    • Cow with liver spot, mushrooms represents the life cycle of Plasmodium, where Anopholes mosquito carry sporozoites in saliva, which mature to trophozoites in the liver, then divide into merozoites that burst from hepatocyte and infect RBCs.
    • Ring shape represents the immature form of Plasmodium, which has a ring form. Merozoite can also form a gametocyte.

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