L26 - MCQ - Acetylcholine and Amino Acids
29 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which compound is an agonist of the nicotinic ACh receptor?

  • Nicotine (correct)
  • Acetylcholine
  • Muscarine
  • α-bungarotoxin
  • Which compound is an antagonist of the ACh ionotropic receptor?

  • α-bungarotoxin (correct)
  • Nicotine
  • Acetylcholine
  • Muscarine
  • Which G protein is activated by M1, M3, and M5 muscarinic ACh receptors?

  • Gq (correct)
  • Go
  • Gs
  • Gi
  • Which compound is a fungal alkaloid that binds with high affinity to muscarinic ACh receptors?

    <p>Muscarine (D)</p> Signup and view all the answers

    Which compound inhibits acetylcholinesterase?

    <p>Sarin nerve gas (A)</p> Signup and view all the answers

    Where is acetylcholinesterase degraded?

    <p>In the synaptic cleft (A)</p> Signup and view all the answers

    What is the most important neurotransmitter for normal brain function?

    <p>Glutamate (C)</p> Signup and view all the answers

    Which ion(s) flux through the NMDA receptor upon Glu binding and membrane depolarization?

    <p>Na+ and Ca2+ (C)</p> Signup and view all the answers

    Which compound is an antagonist of the NMDA receptor?

    <p>MK801 (C)</p> Signup and view all the answers

    Which receptor requires two signals to open: Glu binding and membrane depolarization?

    <p>NMDA receptor (D)</p> Signup and view all the answers

    Which compound was discovered by Henry Dale that produced effects on organs similar to those produced by nerves?

    <p>Acetylcholine (D)</p> Signup and view all the answers

    Who discovered that stimulation of nerves attached to a frog's heart caused the release of chemical substances, one of which was named vagusstoffe?

    <p>Otto Loewi (C)</p> Signup and view all the answers

    What is the name of the receptor that acetylcholine (ACh) can bind to?

    <p>Nicotinic receptor (D)</p> Signup and view all the answers

    How many subunits make up the nicotinic acetylcholine receptor channel?

    <p>5 (A)</p> Signup and view all the answers

    Which subunits are mostly involved in ligand binding in the nicotinic acetylcholine receptor?

    <p>α-subunits (C)</p> Signup and view all the answers

    What is the term for a compound that binds to a receptor and mimics the action of the physiological ligand?

    <p>Agonist (A)</p> Signup and view all the answers

    What is the term for a compound that binds to a receptor and blocks the action of the physiological ligand?

    <p>Antagonist (B)</p> Signup and view all the answers

    What is the name of the transporter responsible for the storage of acetylcholine (ACh) into synaptic vesicles?

    <p>VAChT (A)</p> Signup and view all the answers

    What did Thomas Elliott suggest in 1903 about the transmission of information between neurons?

    <p>The message is transmitted via chemical compound (A)</p> Signup and view all the answers

    Which receptor is mainly postsynaptic and linked to activation of phospholipase C?

    <p>mGluR1 (D)</p> Signup and view all the answers

    What is the role of mGluR inhibitors in memory formation?

    <p>They block memory formation at some synapses (B)</p> Signup and view all the answers

    What causes excitotoxic cell death in stroke?

    <p>Excessive release of glutamate (B)</p> Signup and view all the answers

    Which neurotransmitter is the main inhibitory neurotransmitter in the brain?

    <p>GABA (C)</p> Signup and view all the answers

    Which transporter is responsible for packaging GABA into vesicles?

    <p>VIAAT (C)</p> Signup and view all the answers

    Which type of GABA receptor is structurally related to nicotinic acetylcholine receptors?

    <p>GABAA receptor (B)</p> Signup and view all the answers

    What is the main effect of Valium (diazepam) on GABA-A receptor signaling?

    <p>It increases chloride ion influx (D)</p> Signup and view all the answers

    What is the main function of inhibitory neurotransmitters in presynaptic inhibition?

    <p>To reduce depolarization of the presynaptic nerve terminal (B)</p> Signup and view all the answers

    Which type of neurotransmission is mediated by ionotropic receptors?

    <p>Fast neurotransmission (B)</p> Signup and view all the answers

    What is the effect of inhibitory neurotransmitters on the inside of the cell?

    <p>It becomes more negative (D)</p> Signup and view all the answers

    More Like This

    L26 - male
    35 questions

    L26 - male

    SilentHydrogen avatar
    SilentHydrogen
    L26 GRAMMAR
    63 questions

    L26 GRAMMAR

    CelebratoryYeti avatar
    CelebratoryYeti
    L26. GA - Thyroid & Root of the Neck
    40 questions
    Use Quizgecko on...
    Browser
    Browser