Podcast
Questions and Answers
Which compound is an agonist of the nicotinic ACh receptor?
Which compound is an agonist of the nicotinic ACh receptor?
Which compound is an antagonist of the ACh ionotropic receptor?
Which compound is an antagonist of the ACh ionotropic receptor?
Which G protein is activated by M1, M3, and M5 muscarinic ACh receptors?
Which G protein is activated by M1, M3, and M5 muscarinic ACh receptors?
Which compound is a fungal alkaloid that binds with high affinity to muscarinic ACh receptors?
Which compound is a fungal alkaloid that binds with high affinity to muscarinic ACh receptors?
Signup and view all the answers
Which compound inhibits acetylcholinesterase?
Which compound inhibits acetylcholinesterase?
Signup and view all the answers
Where is acetylcholinesterase degraded?
Where is acetylcholinesterase degraded?
Signup and view all the answers
What is the most important neurotransmitter for normal brain function?
What is the most important neurotransmitter for normal brain function?
Signup and view all the answers
Which ion(s) flux through the NMDA receptor upon Glu binding and membrane depolarization?
Which ion(s) flux through the NMDA receptor upon Glu binding and membrane depolarization?
Signup and view all the answers
Which compound is an antagonist of the NMDA receptor?
Which compound is an antagonist of the NMDA receptor?
Signup and view all the answers
Which receptor requires two signals to open: Glu binding and membrane depolarization?
Which receptor requires two signals to open: Glu binding and membrane depolarization?
Signup and view all the answers
Which compound was discovered by Henry Dale that produced effects on organs similar to those produced by nerves?
Which compound was discovered by Henry Dale that produced effects on organs similar to those produced by nerves?
Signup and view all the answers
Who discovered that stimulation of nerves attached to a frog's heart caused the release of chemical substances, one of which was named vagusstoffe?
Who discovered that stimulation of nerves attached to a frog's heart caused the release of chemical substances, one of which was named vagusstoffe?
Signup and view all the answers
What is the name of the receptor that acetylcholine (ACh) can bind to?
What is the name of the receptor that acetylcholine (ACh) can bind to?
Signup and view all the answers
How many subunits make up the nicotinic acetylcholine receptor channel?
How many subunits make up the nicotinic acetylcholine receptor channel?
Signup and view all the answers
Which subunits are mostly involved in ligand binding in the nicotinic acetylcholine receptor?
Which subunits are mostly involved in ligand binding in the nicotinic acetylcholine receptor?
Signup and view all the answers
What is the term for a compound that binds to a receptor and mimics the action of the physiological ligand?
What is the term for a compound that binds to a receptor and mimics the action of the physiological ligand?
Signup and view all the answers
What is the term for a compound that binds to a receptor and blocks the action of the physiological ligand?
What is the term for a compound that binds to a receptor and blocks the action of the physiological ligand?
Signup and view all the answers
What is the name of the transporter responsible for the storage of acetylcholine (ACh) into synaptic vesicles?
What is the name of the transporter responsible for the storage of acetylcholine (ACh) into synaptic vesicles?
Signup and view all the answers
What did Thomas Elliott suggest in 1903 about the transmission of information between neurons?
What did Thomas Elliott suggest in 1903 about the transmission of information between neurons?
Signup and view all the answers
Which receptor is mainly postsynaptic and linked to activation of phospholipase C?
Which receptor is mainly postsynaptic and linked to activation of phospholipase C?
Signup and view all the answers
What is the role of mGluR inhibitors in memory formation?
What is the role of mGluR inhibitors in memory formation?
Signup and view all the answers
What causes excitotoxic cell death in stroke?
What causes excitotoxic cell death in stroke?
Signup and view all the answers
Which neurotransmitter is the main inhibitory neurotransmitter in the brain?
Which neurotransmitter is the main inhibitory neurotransmitter in the brain?
Signup and view all the answers
Which transporter is responsible for packaging GABA into vesicles?
Which transporter is responsible for packaging GABA into vesicles?
Signup and view all the answers
Which type of GABA receptor is structurally related to nicotinic acetylcholine receptors?
Which type of GABA receptor is structurally related to nicotinic acetylcholine receptors?
Signup and view all the answers
What is the main effect of Valium (diazepam) on GABA-A receptor signaling?
What is the main effect of Valium (diazepam) on GABA-A receptor signaling?
Signup and view all the answers
What is the main function of inhibitory neurotransmitters in presynaptic inhibition?
What is the main function of inhibitory neurotransmitters in presynaptic inhibition?
Signup and view all the answers
Which type of neurotransmission is mediated by ionotropic receptors?
Which type of neurotransmission is mediated by ionotropic receptors?
Signup and view all the answers
What is the effect of inhibitory neurotransmitters on the inside of the cell?
What is the effect of inhibitory neurotransmitters on the inside of the cell?
Signup and view all the answers