Podcast
Questions and Answers
Which of the following is a hallmark of cancer according to the text?
Which of the following is a hallmark of cancer according to the text?
- Resisting cell death
- Sustaining growth signalling
- Enabling replicative immortality (correct)
- Evading growth suppressors
What is the role of telomeres in cell lifespan according to the text?
What is the role of telomeres in cell lifespan according to the text?
- Telomeres shorten genome instability/apoptosis
- Telomeres maintain chromosome ends (correct)
- Telomeres cause cell death
- Telomeres lead to immortalization phase
What is the function of telomerase in normal cells according to the text?
What is the function of telomerase in normal cells according to the text?
- Telomerase leads to immortalization phase
- Telomerase maintains telomere length (correct)
- Telomerase causes cell death
- Telomerase shortens telomeres
Which of the following is a hallmark of cancer?
Which of the following is a hallmark of cancer?
Which of the following is an environmental factor that can lead to genetic changes and cause cancer to develop?
Which of the following is an environmental factor that can lead to genetic changes and cause cancer to develop?
What is the primary site in the body where the cancer first developed in Australia in 2022?
What is the primary site in the body where the cancer first developed in Australia in 2022?
Which theory of carcinogenesis proposes that normal cells are transformed into cancer cells through abnormal cell division?
Which theory of carcinogenesis proposes that normal cells are transformed into cancer cells through abnormal cell division?
Which of the following best describes the concept of carcinogenesis?
Which of the following best describes the concept of carcinogenesis?
Which of the following accurately describes oncogenes?
Which of the following accurately describes oncogenes?
Which hypothesis describes the role of tumor suppressor genes in cancer development?
Which hypothesis describes the role of tumor suppressor genes in cancer development?
Which of the following is NOT a mechanism of oncogene activation?
Which of the following is NOT a mechanism of oncogene activation?
What type of mutation can lead to uncontrolled continuous activity of an oncogene?
What type of mutation can lead to uncontrolled continuous activity of an oncogene?
Which gene is commonly amplified in small-cell lung cancer, breast/ovarian cancer, and leukemias?
Which gene is commonly amplified in small-cell lung cancer, breast/ovarian cancer, and leukemias?
What is the role of the TAX gene in adult T-cell leukemia/lymphoma?
What is the role of the TAX gene in adult T-cell leukemia/lymphoma?
Which type of recurrent rearrangement involves a segment being reversed end to end?
Which type of recurrent rearrangement involves a segment being reversed end to end?
Which mechanism of oncogene activation involves the formation of novel hybrid fusion genes?
Which mechanism of oncogene activation involves the formation of novel hybrid fusion genes?
Which gene is involved in G1 to S transition and is activated by chromosomal translocation in mantle cell lymphoma?
Which gene is involved in G1 to S transition and is activated by chromosomal translocation in mantle cell lymphoma?
Which is NOT an outcome triggered by tumor suppressor activation?
Which is NOT an outcome triggered by tumor suppressor activation?
Which of the following is a mechanism of oncogene activation?
Which of the following is a mechanism of oncogene activation?
What is the function of a growth suppressor?
What is the function of a growth suppressor?
Which of the following is a hallmark of cancer?
Which of the following is a hallmark of cancer?
How can cancer cells resist apoptosis?
How can cancer cells resist apoptosis?
According to the Tissue Organization Field Theory (TOFT), how do carcinogenic agents contribute to cancer development?
According to the Tissue Organization Field Theory (TOFT), how do carcinogenic agents contribute to cancer development?
Which theory of carcinogenesis involves a multi-step process that requires more than one mutation?
Which theory of carcinogenesis involves a multi-step process that requires more than one mutation?
What are epigenetic modifications in the context of cancer development?
What are epigenetic modifications in the context of cancer development?
Which of the following is NOT a characteristic of cancer-associated genes?
Which of the following is NOT a characteristic of cancer-associated genes?
Which type of chromosomal rearrangement is often detected in haematological malignancies and some solid tumors?
Which type of chromosomal rearrangement is often detected in haematological malignancies and some solid tumors?
What are the two mechanisms by which oncogenes can be activated through chromosomal rearrangements?
What are the two mechanisms by which oncogenes can be activated through chromosomal rearrangements?
Which type of abnormality refers to segments within a chromosome that are reversed end to end?
Which type of abnormality refers to segments within a chromosome that are reversed end to end?
Which technique is commonly used to detect gene amplification in haematological malignancies?
Which technique is commonly used to detect gene amplification in haematological malignancies?
