Unravel the Secrets of Myocardial Electrophysiology
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Questions and Answers

Which cells in the heart generate force and are connected by intercalated discs?

  • Conduction cells
  • Desmosome cells
  • Sarcomere cells
  • Work cells (correct)

What initiates the heartbeat in the heart?

  • Work cells
  • Sinoatrial node (correct)
  • Desmosome cells
  • Conduction cells

What is the role of the nerve supply in the heart?

  • To regulate the heartbeat (correct)
  • To generate force
  • To spread electrical events
  • To initiate the heartbeat

What drives the beating of the heart?

<p>Electrical signals generated by the heart itself (B)</p> Signup and view all the answers

What happens to the heart if it is not provided with oxygen and kept moist?

<p>The heart gradually slows down and eventually stops. (D)</p> Signup and view all the answers

Which node in the heart initiates the electrical impulse?

<p>Sino atrial node (SAN) (B)</p> Signup and view all the answers

What happens if the SA node is damaged?

<p>AV node takes over as pacemaker (D)</p> Signup and view all the answers

What is the main cause of the AV delay in the heart?

<p>Very few gap junctions (B)</p> Signup and view all the answers

Which fibers carry the electrical signal to the ventricle muscle cells?

<p>Purkinje fibers (C)</p> Signup and view all the answers

Which type of action potential is exhibited by the SA node and AV node?

<p>Slow response action potential (A)</p> Signup and view all the answers

Which channels are stimulated during hyperpolarization in slow response cardiac fibers?

<p>Funny channels (D)</p> Signup and view all the answers

What is the membrane potential during repolarization in slow response cardiac fibers?

<p>-70 mV (C)</p> Signup and view all the answers

What is the main characteristic of the pacemaker potential in slow response cardiac fibers?

<p>Slow depolarization (B)</p> Signup and view all the answers

Which node in the heart acts as the fastest pacemaker and can be influenced by the autonomic nervous system?

<p>SA node (A)</p> Signup and view all the answers

During phase 0 of the action potential in working cells (ventricular cells), what causes depolarization?

<p>Opening of Na channels (C)</p> Signup and view all the answers

What initiates repolarization during phase 1 of the action potential in working cells?

<p>Closing of Na channels (D)</p> Signup and view all the answers

What causes the plateau phase during phase 2 of the action potential in working cells?

<p>Ca influx &gt; K efflux (A)</p> Signup and view all the answers

What initiates rapid repolarization during phase 3 of the action potential in working cells?

<p>Opening of delayed K channels (B)</p> Signup and view all the answers

Which type of muscle contraction requires intracellular support to induce contraction?

<p>Cardiac muscle contraction (A)</p> Signup and view all the answers

What is the mechanism by which ryanodine receptors in cardiac muscles are operated?

<p>Ca binding (B)</p> Signup and view all the answers

What is the term for the process where the opening of ryanodine receptors allows more Ca in cardiac muscles?

<p>Calcium induced Calcium release (A)</p> Signup and view all the answers

What provides 90% of the intracellular Ca in cardiac muscles?

<p>Intracellular source (A)</p> Signup and view all the answers

Which type of channel blocker is commonly used to control force of contraction in cardiac muscles?

<p>L-type Ca+ channel blocker (A)</p> Signup and view all the answers

Which part of the heart is primarily innervated by the right vagus nerve?

<p>SA node (D)</p> Signup and view all the answers

Which part of the heart is primarily innervated by the left vagus nerve?

<p>AV node (D)</p> Signup and view all the answers

Which part of the heart is lightly innervated by vagal efferent nerves?

<p>Ventricular myocardium (C)</p> Signup and view all the answers

Which receptors are activated by the parasympathetic nervous system in the heart?

<p>Muscarinic ACh receptors (A)</p> Signup and view all the answers

Which receptors are activated by the sympathetic nervous system in the heart?

<p>B1-adrenergic receptors (C)</p> Signup and view all the answers

What effect does the sympathetic nervous system have on the cardiac excitability of the fast response action potential in cardiac muscle?

<p>Positive bathmotropic effect (D)</p> Signup and view all the answers

What effect does the sympathetic nervous system have on the rate and rhythm of the fast response action potential in cardiac muscle?

<p>Positive chronotropic effect (B)</p> Signup and view all the answers

What effect does the sympathetic nervous system have on the conduction speed of the fast response action potential in cardiac muscle?

<p>Positive dromotropic effect (B)</p> Signup and view all the answers

Which ion is primarily responsible for speeding up the rate of pacemaker depolarization in the presence of sympathetic nervous system activation?

<p>Na+ (D)</p> Signup and view all the answers

What effect does the parasympathetic nervous system have on the rate of firing of the slow response action potential in cardiac muscle?

<p>Decreases the rate of firing (A)</p> Signup and view all the answers

Which channels are inhibited by the parasympathetic nervous system in order to slow down the rate of pacemaker depolarization?

<p>Ca++ channels (D)</p> Signup and view all the answers

Why does smoking increase the likelihood of a heart attack?

<p>It helps atheroma to develop (B)</p> Signup and view all the answers

Which type of muscle does not tetanize?

<p>Cardiac muscle (B)</p> Signup and view all the answers

During which phase of the action potential in working cells does depolarization occur?

<p>Phase 0 (A)</p> Signup and view all the answers

What is the duration of the absolute refractory period?

<p>2/3rd part of the cardiac AP (C)</p> Signup and view all the answers

What happens if a new stimulus occurs during the absolute refractory period?

<p>It is unable to elicit a new response (A)</p> Signup and view all the answers

What is the effect of the relative refractory period on the generation of an action potential?

<p>A stronger stimulus is needed to generate an action potential (B)</p> Signup and view all the answers

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