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Unlocking the Mysteries of Hemolytic Anemias and Blood Disorders

Test your knowledge on various types of hemolytic anemias, neutropenia, and lymphopenia with this informative quiz. Discover the differences between warm and cold AIHA, and learn about the causes and treatments for these conditions. Explore the various types of hemolytic anemias and their associated symptoms, as well as the causes and effects of neutropenia and lymphopenia. Challenge yourself with questions on eosinopenia and how it can be caused by certain medical conditions.

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Questions and Answers

What is the difference between warm and cold AIHA?

Warm AIHA is chronic and caused by IgG, while cold AIHA is acute and caused by IgM and complement.

What is the characteristic feature of neutropenia?

Absolute neutrophil count < 1500 cells/mm3

What can cause eosinopenia?

Cushing syndrome and glucocorticoids

Which condition can cause microangiopathic hemolytic anemia?

<p>Hypertensive emergency</p> Signup and view all the answers

How is warm AIHA treated?

<p>Steroids and splenectomy</p> Signup and view all the answers

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Study Notes

  • Extrinsic hemolytic anemias include autoimmune, drug-induced, microangiopathic, and macroangiopathic types.
  • Warm AIHA is a chronic anemia caused by IgG, while cold AIHA is an acute anemia caused by IgM and complement.
  • Spherocytes and agglutinated RBCs are seen in warm AIHA, while schistocytes are seen in microangiopathic and macroangiopathic hemolytic anemias.
  • Hemolytic anemia can also be caused by infection, such as malaria and Babesia.
  • Neutropenia is characterized by an absolute neutrophil count < 1500 cells/mm3 and can be caused by sepsis, drugs, and autoimmune disorders.
  • Lymphopenia is characterized by an absolute lymphocyte count < 1500 cells/mm3 and can be caused by HIV, radiation, and sepsis.
  • Eosinopenia is characterized by an absolute eosinophil count < 30 cells/mm3 and can be caused by Cushing syndrome and glucocorticoids.
  • Glucocorticoids can cause neutrophilia despite causing lymphopenia and eosinopenia.
  • Warm AIHA can be treated with steroids, rituximab, and splenectomy, while cold AIHA can be treated with cold avoidance and rituximab.
  • Microangiopathic hemolytic anemia can be seen in DIC, TTP/HUS, SLE, HELLP syndrome, and hypertensive emergency.

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