10 Questions
What is the physiological role of COX-1 in the stomach?
Inhibits gastric acid secretion and enhances the formation of gastric mucosa
What is the physiological role of COX-1 in platelets?
Increases platelet aggregation and causes vasoconstriction
What is the physiological role of COX-2 in the kidney?
Important for the maintenance of renal blood flow & normal renal function
What is the main difference between COX-1 and COX-2?
COX-1 is constitutive while COX-2 is inducible and responsible for inflammation, fever & pain
What are the clinical indications of NSAIDs?
Relieving mild to moderate pain and reducing inflammation
Which enzyme is responsible for maintaining renal blood flow and normal renal function?
COX-2
What is the physiological role of COX-1 in platelets?
Increases platelet aggregation
What is the primary function of COX-1 in the stomach?
Enhances gastric mucosa formation
Which COX isoenzyme is responsible for inflammation, fever, and pain?
COX-2
5
NSAIDs are less powerful than opioids but adequate for mild to moderate pain.
Test your knowledge about the physiological roles of cyclooxygenase (COX) enzyme and its relationship with prostaglandins. Learn about the different COX isoenzymes and their specific functions in the body.
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