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Questions and Answers
What is the physiological role of COX-1 in the stomach?
What is the physiological role of COX-1 in the stomach?
- Reduces the formation of gastric mucosa and promotes peptic ulcer
- Stimulates gastric acid secretion and decreases gastric blood flow
- Has no significant role in stomach physiology
- Inhibits gastric acid secretion and enhances the formation of gastric mucosa (correct)
What is the physiological role of COX-1 in platelets?
What is the physiological role of COX-1 in platelets?
- Has no effect on platelet function
- Increases platelet aggregation and causes vasoconstriction (correct)
- Inhibits platelet aggregation and prevents clot formation
- Promotes bleeding time and clot formation
What is the physiological role of COX-2 in the kidney?
What is the physiological role of COX-2 in the kidney?
- Promotes renal vasoconstriction & decreases renal blood flow
- Important for the maintenance of renal blood flow & normal renal function (correct)
- Has no significant role in kidney physiology
- Induces inflammation & impairs renal function
What is the main difference between COX-1 and COX-2?
What is the main difference between COX-1 and COX-2?
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What are the clinical indications of NSAIDs?
What are the clinical indications of NSAIDs?
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Which enzyme is responsible for maintaining renal blood flow and normal renal function?
Which enzyme is responsible for maintaining renal blood flow and normal renal function?
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What is the physiological role of COX-1 in platelets?
What is the physiological role of COX-1 in platelets?
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What is the primary function of COX-1 in the stomach?
What is the primary function of COX-1 in the stomach?
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Which COX isoenzyme is responsible for inflammation, fever, and pain?
Which COX isoenzyme is responsible for inflammation, fever, and pain?
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5
5
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