Immunology Lec 1

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Which of the following are the two branches of the immune system?

Innate and acquired

What are the main functions of the immune system?

Prevent infections, control infections, and eliminate pathogens

What are the types of immunity mentioned in the text?

Innate and passive

What are the effector mechanisms within each type of immunity?

Complement system and phagocytosis

Which component of the immune system responds to non-self antigens rather than specific pathogens?

Macrophages

What is the single most important attribute of the immune system as stated in the text?

Ability to differentiate self from non-self

What is the primary function of lymph nodes in the immune system?

Removal of antigens

Which component of the immune system is responsible for antibody production?

B cells

What is the function of PAMP recognition in the innate immune system?

Recognition of specific pathogens

Which blood component is involved in immunity and circulates in/out of the bloodstream?

Leukocytes

What is the network of vessels and nodes that circulate and filter lymph called?

Lymphatic system

Which type of immunity responds to non-self antigens rather than specific pathogens?

Innate immunity

Which type of immune response involves the production of antibodies to protect against extracellular pathogens and products?

Humoral immunity

Which branch of adaptive immunity protects against intracellular pathogens and is carried out by specialized T cells?

Cell-mediated immunity

What type of immune response is non-specific, always on, and relies on chemical and cellular barriers?

Innate immunity

Which type of immunity protects against pathogens at the interface with mucosal tissues or within mucosal tissues and makes up most of our adaptive immune responses?

Mucosal immunity

What are the key cellular components of adaptive immunity?

Lymphocytes, leukocytes, and antigen-presenting cells

How does innate immunity regulate adaptive immunity?

Through complement proteins and cytokines

What type of immune response involves interactions between the innate and adaptive immune branches, with each branch affecting the other?

Adaptive immune responses

What triggers an immune response through recognition of conserved structures on many pathogens but not on self?

Aureus bacterium

What is a specific, targeted response that gets better with each encounter and provides memory for the next encounter?

Adaptive immunity

Which type of immunity is non-specific, always on, relying on chemical and cellular barriers?

Innate immunity

What triggers an immune response through recognition of conserved structures on many pathogens but not on self?

PAMP recognition

Which branch of adaptive immunity protects against intracellular pathogens and is carried out by specialized T cells?

Cell-mediated immunity

How does adaptive immunity regulate innate immunity?

Through T cells

What are the effector mechanisms within humoral immunity?

Antibody production

Which type of immune response involves interactions between the innate and adaptive immune branches, with each branch affecting the other?

Adaptive immunity

What is the network of vessels and nodes that circulate and filter lymph called?

Lymphatic system

What is the primary function of lymph nodes in the immune system?

Filter lymph and trap pathogens

Which component of the immune system responds to non-self antigens rather than specific pathogens?

Innate immunity

What are the key cellular components of adaptive immunity?

Lymphocytes, leukocytes, and antigen-presenting cells

Which immune response involves a specific, targeted response that improves with each encounter and provides memory for the next encounter?

Adaptive immunity

What triggers an immune response through recognition of conserved structures on many pathogens but not on self?

PAMP recognition

What are the key cellular components of adaptive immunity?

B cells and T cells

What is the network of vessels and nodes that circulate and filter lymph called?

Lymphatic system

What is the primary function of lymph nodes in the immune system?

Filter lymph

Which branch of adaptive immunity protects against intracellular pathogens and is carried out by specialized T cells?

Cellular immunity

What type of immune response is non-specific, always on, and relies on chemical and cellular barriers?

Innate immunity

Which component of the immune system responds to non-self antigens rather than specific pathogens?

B cells

What are the main functions of the immune system?

Provide defense against infection and disease

What component of the immune system is responsible for antibody production?

B cells

Which of the following is NOT an effector mechanism of innate immunity?

Antibody neutralization

What is the primary function of lymph nodes in the immune system?

Filter interstitial fluids and remove antigens

Which component of the immune system circulates in/out of the bloodstream and lymphatic system?

Leukocytes

What is the difference between lymph and interstitial fluid?

Location within the body

Which type of immunity responds to non-self antigens rather than specific pathogens?

Innate immunity

What is the single most important attribute of the immune system according to the text?

Antigen-specific receptors (antibodies, TCRs, MHCs)

What happens if the immune system fails to recognize non-self antigens?

Autoimmune disease

What are the two parts/activities of an immune response mentioned in the text?

Recognition of antigen and effector mechanisms

What is the network of vessels and nodes that circulate and filter plasma-derived fluid called?

Lymphatic system

Which type of immunity is always on, non-specific, and relies on chemical and cellular barriers?

Innate immunity

Study Notes

  • Aureus bacterium triggers an immune response through recognition of conserved structures on many pathogens but not on self

  • Innate immunity initiates inflammatory responses to remove or contain pathogens and help in tissue repair

  • Adaptive immunity is a specific, targeted response that gets better with each encounter and provides memory for next encounter

  • Adaptive immunity can be divided into three types: humoral, cell-mediated, and mucosal

  • Humoral immunity involves the production of antibodies to protect against extracellular pathogens and products

  • Cell-mediated immunity protects against intracellular pathogens and is carried out by specialized T cells

  • Mucosal immunity protects against pathogens at the interface with mucosal tissues or within mucosal tissues and makes up most of our adaptive immune responses

  • Lymphocytes, leukocytes, and antigen-presenting cells are key cellular components of adaptive immunity

  • Adaptive immune responses involve interactions between the innate and adaptive immune branches, with each branch affecting the other

  • Innate immunity regulates adaptive immunity through complement proteins and cytokines, while adaptive immunity regulates innate immunity through T cells and antibodies

  • Innate immunity is non-specific and always on, relying on chemical and cellular barriers, while adaptive immunity is specific and requires activation and memory.

  • Aureus bacterium triggers an immune response through recognition of conserved structures on many pathogens but not on self

  • Innate immunity initiates inflammatory responses to remove or contain pathogens and help in tissue repair

  • Adaptive immunity is a specific, targeted response that gets better with each encounter and provides memory for next encounter

  • Adaptive immunity can be divided into three types: humoral, cell-mediated, and mucosal

  • Humoral immunity involves the production of antibodies to protect against extracellular pathogens and products

  • Cell-mediated immunity protects against intracellular pathogens and is carried out by specialized T cells

  • Mucosal immunity protects against pathogens at the interface with mucosal tissues or within mucosal tissues and makes up most of our adaptive immune responses

  • Lymphocytes, leukocytes, and antigen-presenting cells are key cellular components of adaptive immunity

  • Adaptive immune responses involve interactions between the innate and adaptive immune branches, with each branch affecting the other

  • Innate immunity regulates adaptive immunity through complement proteins and cytokines, while adaptive immunity regulates innate immunity through T cells and antibodies

  • Innate immunity is non-specific and always on, relying on chemical and cellular barriers, while adaptive immunity is specific and requires activation and memory.

Test your knowledge of the immune system with this quiz covering the two branches of the immune system and their distinctions. This quiz is based on learning objectives from Abbas: Cellular and Molecular Immunology, 2018.

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