Seizure therapeutics 1
40 Questions
2 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Awareness that a seizure is about to occur _______

prodrome

At least ONE seizure that is not provoked and that can occur again _______

epilepsy

Refractory seizures occur if failure of 2 or more ASMs AND 1 or more seizures per month over _______

18 months

status epilepticus: Continuous seizure lasting _____ or more OR 2 or more seizure without full recovery

<p>5 min</p> Signup and view all the answers

What is the T1 for absense seizures? ______ mins

<p>15</p> Signup and view all the answers

Diazepam rectal gel is a seizure ______ medication.

<p>rescue</p> Signup and view all the answers

Which of the following is NOT a known cause of seizures?

<p>Excessive carbohydrate intake</p> Signup and view all the answers

Prodrome in relation to seizures refers to:

<p><em>Awareness that a seizure is about to occur</em></p> Signup and view all the answers

Which of the following is a negative predictor of discontinuation of anti-seizure medications?

<p>Multiple seizure types in the same person</p> Signup and view all the answers

What is a risk associated with the abrupt withdrawal of anti-seizure medications?

<p>Seizure recurrence</p> Signup and view all the answers

When should carbamazepine (Tegretol) be avoided?

<p>In absence seizures</p> Signup and view all the answers

What is the major active metabolite shared by eslicarbazepine acetate and oxcarbazepine?

<p>Carbamazepine</p> Signup and view all the answers

Which of the following dermatologic risks is associated with eslicarbazepine acetate?

<p>Stevens-Johnson Syndrome</p> Signup and view all the answers

What is the black box warning associated with lamotrigine (Lamictal)?

<p>Risk of serious skin rashes including SJS and TEN</p> Signup and view all the answers

When does SJS and TEN typically develop in patients taking lamotrigine (Lamictal)?

<p>Within 2-8 weeks</p> Signup and view all the answers

What are the warnings and precautions associated with levetiracetam (Keppra) and brivaracetam?

<p>Behavioral and psychiatric disturbances</p> Signup and view all the answers

What is a serious adverse effect associated with carbamazepine (Tegretol)?

<p>Agranulocytosis</p> Signup and view all the answers

Why should carbamazepine (Tegretol) be taken with food?

<p>To decrease stomach upset</p> Signup and view all the answers

Which of the following is true about carbazepine ?

<p>It can induce its own metabolism</p> Signup and view all the answers

What should be closely monitored in patients taking oxcarbazepine (Trileptal)?

<p>CMP levels</p> Signup and view all the answers

Which statement is true regarding the risk of hyponatremia between carbamazepine (Tegretol) and oxcarbazepine (Trileptal)?

<p><strong>Hyponatremia</strong> is more common with oxcarbazepine (Trileptal)</p> Signup and view all the answers

Which medication significantly decreases lamotrigine serum concentrations?

<p>Oral contraceptions</p> Signup and view all the answers

What is not an AE associated with valproate (Depakote) ?

<p>Weight loss</p> Signup and view all the answers

When is the typical timeframe for the development of serious skin rashes, including SJS and TEN, with lamotrigine (Lamictal)?

<p>2-8 weeks</p> Signup and view all the answers

Which of the following is a specific warning/precaution for levetiracetam (Keppra) and brivaracetam?

<p>Potential behavioral and psychiatric disturbances</p> Signup and view all the answers

Which drug DOES NOT require renal dose adjustments?

<p>Lamotrigine</p> Signup and view all the answers

What is the schedule classification of brivaracetam?

<p>CV</p> Signup and view all the answers

What is a common first-line agent for focal seziures according to the text?

<p>Levetiracetam (Keppra)</p> Signup and view all the answers

Which medication is most commonly used in the treatment of neuropathic pain?

<p>Gabapentin</p> Signup and view all the answers

Which is not a Boxed warning for Valproate?

<p>New onset aggression and psychiatric disturbances</p> Signup and view all the answers

Valproate is contraindicated in ____ ____?

<p>Mitochondrial Disorders</p> Signup and view all the answers

Valproate Therapeutic Range

<p>50-125 mcg/ml</p> Signup and view all the answers

IV use of Brivaracetam is limited to ___ consecutive days

<p>4</p> Signup and view all the answers

What is a contraindication for phenytoin and fosphenytoin?

<p>Sinus bradychardia</p> Signup and view all the answers

Match the drug with the Box warning

<p>Phenytoin = CV risk rapid infusion Perampanel = psychiatric and behavioral disturbances Felbamate = Aplastic Anemia Valproate = Pancreatits</p> Signup and view all the answers

Felbamate should be discontinued if ___ are 2x normal upper limit normal

<p>LFTs</p> Signup and view all the answers

Which drug is an NMDA-R blocker

<p>Felbamate</p> Signup and view all the answers

T/F: Pentobarbital is a GABA-A Pam that increases channel opening time

<p>True</p> Signup and view all the answers

Primidone is metablized by CYP____ into Phentobarbital and PEMA

<p>CYP2C9</p> Signup and view all the answers

Which ASM is NOT contraindicated in Familial Short QT syndrome

<p>Epidolex</p> Signup and view all the answers

More Like This

Seizure Terms Quiz
10 questions

Seizure Terms Quiz

TrustingUvite avatar
TrustingUvite
Epilepsy and Seizure Definitions Quiz
36 questions
Seizures and Epilepsy Overview
6 questions
Use Quizgecko on...
Browser
Browser