Understanding Positive Psychology & Mental Health

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Questions and Answers

How does 'positive psychology' relate to mental health?

  • It examines the genetic predispositions to mental disorders.
  • It studies the characteristics that compose mental health. (correct)
  • It emphasizes pharmacological interventions for mental health.
  • It focuses on the absence of mental illness symptoms.

Which of the following is an element of mental health?

  • The ability to form healthy relationships (correct)
  • Suppression of emotions during adversity
  • Disregard for self-esteem and sexuality
  • Maintaining rigid expectations

What is a crucial component of the American Psychiatric Association's definition of mental illness?

  • An expected response to a particular event
  • A clinically significant behavioral or psychological syndrome (correct)
  • A transient feeling of discomfort
  • A pattern of normal behavior

Maladaptive responses to stress are characterized by:

<p>Interference with social or occupational functioning (D)</p> Signup and view all the answers

In a psychiatric assessment, what aspect of the client's history is important to consider beyond just the presenting problem?

<p>Cognitive abilities and perceptions (A)</p> Signup and view all the answers

During the 'resistance stage' of the General Adaptation Syndrome, what is the body attempting to do?

<p>Adapt to the stress level and return to homeostasis. (B)</p> Signup and view all the answers

What guiding principle determines the appropriate 'level of care' in mental health treatment?

<p>The least restrictive setting alternative for adequate treatment (D)</p> Signup and view all the answers

The Diagnostic and Statistical Manual of Mental Disorders (DSM) is primarily used for:

<p>Classifying and diagnosing mental disorders (C)</p> Signup and view all the answers

Which of the following is NOT one of the interdependent components of psychotherapeutic management?

<p>Patient's financial status (A)</p> Signup and view all the answers

What role does a psychiatric mental health nurse play in milieu management?

<p>Overseeing the therapeutic community around the clock (C)</p> Signup and view all the answers

According to Hildegard Peplau, in which of the following ways do nurses assist individuals in need of mental health services?

<p>Technical expert (D)</p> Signup and view all the answers

What is a key distinction between a social and a therapeutic relationship?

<p>Therapeutic relationships are focused on the patient's needs and goals. (C)</p> Signup and view all the answers

Which of the following is essential for a Psychiatric Mental Health Nurse to successfully build therapeutic relationships with patients?

<p>Demonstrating skill at building trust (D)</p> Signup and view all the answers

What does the term 'therapeutic use of self' refer to in the context of a nurse-patient relationship?

<p>Employing personal aspects to benefit the patient (D)</p> Signup and view all the answers

What activity is associated with the working stage of the Therapeutic Nurse-Patient Relationship?

<p>In-depth data collection (A)</p> Signup and view all the answers

When using the BATHE technique in patient communication, what does the 'H' stand for?

<p>Handling (B)</p> Signup and view all the answers

What is the primary goal of milieu therapy?

<p>Scientific structuring of the environment (A)</p> Signup and view all the answers

In a therapeutic milieu, what is the perspective on patient interactions?

<p>They should be approached as opportunities for interventions. (A)</p> Signup and view all the answers

Which of the following best describes the role that a mental health technician plays as part of the interdisciplinary team?

<p>Assisting hospital staff. (B)</p> Signup and view all the answers

What is the main objective of an 'Educational Group' within a therapeutic setting?

<p>To convey knowledge and information (D)</p> Signup and view all the answers

Which of the following is considered a primary function of a therapeutic group?

<p>Providing empowerment (D)</p> Signup and view all the answers

In the milieu setting, what is the registered nurse's priority related to patient activities?

<p>Patient safety (C)</p> Signup and view all the answers

When is it ethically permissible to administer medication without informed consent?

<p>If there is a documented court order (C)</p> Signup and view all the answers

What is a key consideration when contemplating the use of medication in psychopharmacology?

<p>Considering the effect of target symptoms (A)</p> Signup and view all the answers

Which neurotransmitter is most closely associated with Alzheimer's disease?

<p>Acetylcholine (A)</p> Signup and view all the answers

How does aging generally affect drug absorption in the elderly?

<p>Decreased intestinal motility (D)</p> Signup and view all the answers

Which of the following is a potential side effect of neuroleptics in elderly patients that requires careful monitoring?

<p>Orthostatic hypotension (B)</p> Signup and view all the answers

What characterizes Schizophrenia?

<p>Disturbances in perception (D)</p> Signup and view all the answers

What is the primary focus of typical antipsychotic medications in treating schizophrenia?

<p>Treating positive symptoms such as hallucinations and delusions (B)</p> Signup and view all the answers

Atypical antipsychotics are known for treating which symptoms of schizophrenia?

<p>Both positive and negative symptoms (A)</p> Signup and view all the answers

Why is regular blood monitoring essential for patients taking Clozapine (Clozaril)?

<p>Due to the risk of agranulocytosis (B)</p> Signup and view all the answers

The extrapyramidal symptoms (EPS) are adverse side effects from what imbalance?

<p>Acetylcholine and dopamine (A)</p> Signup and view all the answers

What is the pharmacological action of anticholinergic medications prescribed with antipsychotics?

<p>Restore dopamine and acetylcholine balance (A)</p> Signup and view all the answers

Blurred vision, as a side effect of anticholinergics, requires which nursing intervention?

<p>Caution with driving (C)</p> Signup and view all the answers

Tardive dyskinesia (TD) is characterized by what set of symptoms?

<p>Bizarre facial and tongue movements (B)</p> Signup and view all the answers

What is a rare, but potentially fatal side effect of antipsychotic medication?

<p>Neuroleptic Malignant Syndrome (NMS) (D)</p> Signup and view all the answers

What is the cardinal symptom for Neuroleptic Malignant Syndrome (NMS)?

<p>Elevated temperature (B)</p> Signup and view all the answers

What is an important education point regarding Monoamine Oxidase Inhibitors (MAOIs)?

<p>Avoiding tyramine-rich foods (B)</p> Signup and view all the answers

Why is a short supply of antidepressants recommended, especially when initiating treatment?

<p>To limit suicide potential (C)</p> Signup and view all the answers

What is a sign/symptom of Serotonin Syndrome?

<p>Myoclonus (D)</p> Signup and view all the answers

What is the therapeutic range for Lithium?

<p>0.6-1.2 mEq/L (A)</p> Signup and view all the answers

According to the General Adaptation Syndrome, during the alarm stage, the body prepares to respond to a stressor by:

<p>Activating the 'fight or flight' response. (C)</p> Signup and view all the answers

What is the guiding principle for determining the right level of mental health care?

<p>Selecting the least restrictive setting that still provides effective treatment. (B)</p> Signup and view all the answers

In the context of psychotherapeutic management, what signifies the relationship among therapeutic nurse-patient interactions, milieu management, and psychopharmacology?

<p>They are interdependent components essential for a holistic treatment approach. (D)</p> Signup and view all the answers

How does a psychiatric mental health nurse utilize the nursing process within a therapeutic milieu?

<p>To manage the therapeutic environment and ensure patient needs are met around the clock. (D)</p> Signup and view all the answers

In Hildegard Peplau's framework, what role involves the nurse providing specific answers related to the patient's healthcare questions?

<p>Resource Person (C)</p> Signup and view all the answers

What underlying element is key to a Psychiatric Mental Health Nurse's skill in establishing effective therapeutic relationships?

<p>Exhibiting skill at trust, congruence, empathy, acceptance, and positive regard. (A)</p> Signup and view all the answers

During the working stage of a therapeutic nurse-patient relationship, which activity is most indicative of progress?

<p>Promoting change and teaching new skills. (D)</p> Signup and view all the answers

Within the BATHE technique, what aspect of the patient's experience does the 'T' (Trouble) specifically explore?

<p>The most bothersome aspect of the patient's current situation. (A)</p> Signup and view all the answers

How does the concept of 'owning their own behavior' apply to patients within a therapeutic milieu?

<p>Patients are encouraged to take responsibility for the consequences of their actions. (A)</p> Signup and view all the answers

In a therapeutic group setting, what function is served when members share personal experiences and offer encouragement to one another?

<p>Camaraderie (B)</p> Signup and view all the answers

What is the psychiatric nurse's key responsibility in ensuring safety related to patient activities?

<p>Closely monitoring patients' movements and activities to prevent harm. (D)</p> Signup and view all the answers

A patient has been prescribed a medication that requires informed consent; what critical information must be included in the consent process?

<p>Maximum dosages, intended benefits, and potential risks. (B)</p> Signup and view all the answers

In the context of psychopharmacology, what is the most crucial consideration when using medications?

<p>Using the lowest effective dose for sufficient time to target symptoms. (B)</p> Signup and view all the answers

Which of the following neurotransmitters is associated with mania and depression?

<p>Serotonin (B)</p> Signup and view all the answers

How does decreased intestinal motility in elderly individuals affect drug absorption?

<p>It decreases the rate of drug absorption. (A)</p> Signup and view all the answers

What is a common side effect of neuroleptics in elderly patients that necessitates careful monitoring?

<p>Orthostatic hypotension (B)</p> Signup and view all the answers

What symptoms of schizophrenia are addressed by Atypical antipsychotics?

<p>Both positive and negative symptoms (A)</p> Signup and view all the answers

Extrapyramidal symptoms (EPS) result from an imbalance of which neurotransmitters?

<p>Acetylcholine and dopamine (B)</p> Signup and view all the answers

What is the purpose of prescribing anticholinergic medications alongside antipsychotics?

<p>To counteract extrapyramidal symptoms (B)</p> Signup and view all the answers

What nursing intervention is appropriate for a patient experiencing blurred vision as a side effect of anticholinergic medication?

<p>Recommend the use of sunglasses (D)</p> Signup and view all the answers

The primary initial symptom of Neuroleptic Malignant Syndrome involves:

<p>Elevated temperature (A)</p> Signup and view all the answers

What dietary consideration is critical for patients taking Monoamine Oxidase Inhibitors (MAOIs)?

<p>Avoiding foods high in tyramine to prevent hypertensive crisis (A)</p> Signup and view all the answers

When starting a patient on antidepressant medication, why is it important to dispense only a limited supply?

<p>To reduce the risk of intentional overdose (B)</p> Signup and view all the answers

Which of the following signs or symptoms indicates Serotonin Syndrome?

<p>Severe muscle rigidity and hyperthermia (C)</p> Signup and view all the answers

A nurse is assessing therapeutic communication with a patient and uses the acronym BATHE. What does the acronym BATHE stand for?

<p>Background, Affect, Troubles, Handling, Empathy (B)</p> Signup and view all the answers

A nurse is working with a patient who is experiencing mania, what is first line treatment for bipolar disorder?

<p>Lithium (C)</p> Signup and view all the answers

What lab value is most important to monitor when a patient is prescribed valproic acid?

<p>LFTs (B)</p> Signup and view all the answers

A patient with suspected benzodiazepine overdose has been admitted, which medication reversal agent is most appropriate?

<p>Flumazenil (C)</p> Signup and view all the answers

Which group of medications are found to be dangerous if they are mixed with CNS depressants?

<p>Benzodiazepines (C)</p> Signup and view all the answers

A patient is newly prescribed Buspirone, what important teaching is needed regarding onset of action?

<p>Relief of anxiety within 7-10 days, but takes 1-6 weeks maximum benefit (B)</p> Signup and view all the answers

A patient is newly prescribed Lithium and asks questions about what side effects to look out for; what should be included in the nurses response?

<p>Contact MD with V, severe tremor, &gt; sedation muscle weakness, vertigo (B)</p> Signup and view all the answers

A patient taking an antidepressant is admitted to the emergency department and is demonstrating signs of restlessness, agitation, and shivering; which condition should the nurse suspect?

<p>Serotonin Syndrome (D)</p> Signup and view all the answers

A nurse is preparing to administer medications and notes there is a lack of consent in the chart; what is the best action?

<p>Hold the dose (A)</p> Signup and view all the answers

A patient is newly ordered to take the a Monoamine Oxidase Inhibitors (MAOIs); what are the important foods to avoid?

<p>Tyramine (A)</p> Signup and view all the answers

Flashcards

Positive psychology

The study of the characteristics that make up mental health.

Resilience

The ability to bounce back from adversity.

Mental Illness

A clinically significant behavioral or psychological syndrome associated with distress or disability.

Alarm stage

Immediate physiological response to a threat (fight or flight).

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Exhaustion stage

Prolonged stress adaptation that depletes the body's resources.

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Psychiatric Nurse's role

Using the nursing process to manage the therapeutic community around the clock.

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Hildegard Peplau

Six nursing roles were defined in assisting people with mental health services.

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Therapeutic Use of Self

The ability of the nurse to use aspects of his personality, values, and feelings to establish a therapeutic relationship with patients.

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Orientation Stage

Building trust and setting an agenda when working with a client.

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Termination Stage

The last stage of the nurse-client relationship involving evaluating goal attainment and summarizing progress.

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BATHE Technique

A communication technique to help patients identify problems and coping strategies.

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Milieu Therapy

Scientifically structuring the environment to effect behavioral changes and improve mental health.

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Task Group

Group that accomplishes a specific outcome

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Educational Group

Group that conveys knowledge and information.

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Group definition

A collection of individuals founded on shared commonalities of interest, values, norms, or purpose.

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Safety Considerations

Supervising patient movements and activities

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Medication Administration

Informed consent, must identify medication, dosages, benefits and risks.

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Acetylcholine

Alzheimer's Disease and Parkinsonism

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Dopamine

Schizophrenia & Parkinsonism

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GABA

Anxiety Disorders

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Norepinephrine

Mania & Depression

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Serotonin

Mania & Depression

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Psychotropics

Medications that require informed consent

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Absorption

decreased intestinal motility and blood flow to the gut

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Distribution

Decreased body water, increased body fat, decreased plasma proteins

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Metabolism

Decreased blood flow to liver and decreased liver function

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Excretion

Diminished kidney function and decreased creatinine clearance

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Schizophrenia

Diagnostic term with disturbances in perception, thought processes, and reality testing.

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Typical Antipsychotics

Addresses positive symptoms like hallucinations and delusions.

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Atypical Antipsychotics

Addresses both positive and negative symptoms of schizophrenia.

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Extrapyramidal symptoms

An imbalance between acetylcholine and dopamine

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treatment for NMS

Dantrolene (Dantrium) and Bromocriptine

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Mood Disorders

Antidepressants are used to major depression, panic disorder and other anxiety disorders

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Examples of SSRI's

Fluoxetine (Prozac) & Sertraline (Zoloft)

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MAOI's & cyclic antidepressants

Medication with cardiovascular toxicity associated with it

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Examples of Novel Antidepressants

Bupropion (Wellbutrin, Zyban)

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Antimanic agent

Lithium carbonate (Lithium)

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Alternative to Lithium

Carbamazepine (Tegretol) and Valproic Acid (Depakote)

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Benzodiazepines

Clonazepam (Klonopin) & Lorazepam (Ativan)

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Anxiolytics

Anxiety Disorders, OCD, Panic Disorder

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Benzos

Enhance GABA

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Benzodiazepines Teaching

Benzos not intended for minor stresses

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Study Notes

  • Positive psychology studies the characteristics that make up mental health.
  • Mental health includes the ability to enjoy life and having resilience, which is the ability to bounce back from adversity.
  • Mental health depends on having balance in life and having emotional and cognitive flexibility.
  • Mentally healthy people are in the process of realizing their potential.
  • Mental health includes the ability to form healthy relationships, have healthy self-esteem and sexuality, and have a perspective on death, dying, and loss.
  • The American Psychiatric Association defines mental illness as a clinically significant behavioral or psychological syndrome or pattern.
  • Mental illnesses are associated with present distress, increased risk of suffering death, pain disability, or an impairment loss of freedom, but is not merely an expectable response to a particular event.
  • Mental illness manifests as maladaptive responses to stressors from the internal or external environment.
  • These responses are evidenced by thoughts, feelings, and behaviors that are incongruent with cultural norms and interfere with the individual’s functioning.

Psych Assessment

  • The information gathered will explain why the patient is seeking help.
  • Information includes the client's name, race/ethnic data, marital status, #/ages of children and siblings, living arrangements, occupation, education, religious affiliations
  • Information to gather includes feelings of depression, anxiety, hopelessness, being overwhelmed, suspiciousness or confusion, and recent difficulties or alterations in relationships, usual level of functioning, behavior, perceptions and cognitive abilities.
  • Somatic changes to note include constipation, diarrhea, insomnia, lethargy, changes in weight, anorexia, palpitations, pruritus, nausea, vomiting, and headache.
  • Important family history to gather includes childhood, caregiver information, abuse, and parental drinking history.
  • Assess for use of drugs, the effect on the family, any physical or mental problems, and how it has affected the family.
  • Relevant personal history includes previous illness, hospitalization, education- highest grade completed and special skills.
  • Occupational background, where, how long employed, and job description important.
  • Social patterns include importance of friends and usual daily activities.
  • Sexual patterns include if active, orientation, and any difficulties.
  • Note interests and abilities, including spare time activities, what the patient is good at, and if it gives pleasure.
  • Substance abuse profiles should note medications the patient is taking and if they use alcohol or drugs.
  • Assess the patient's stress coping methods.

General Adaption Syndrome

  • Alarm stage: there is an immediate physiological response to a threat or perceived threat (fight or flight).
  • Resistance stage: If the stress continues, the body adapts to the levels of stress and attempts to return to homeostasis.
  • Exhaustion stage: Prolonged exposure and stress adaptation can deplete the body’s resources; without intervention, death is a possibility.

Levels of Care

  • Right to treatment in the least restrictive setting alternative is a guiding principle.
  • Care environments range from outpatient primary healthcare and counselor, to emergency department, to in-patient psychiatric hospitalization, to home, board and care, residential facility, assisted living or homeless shelter.
  • Inpatient psychiatric care could be voluntary or involuntary and commitment legal status.

Diagnostic and Statistical Manual for Mental Disorders-V-TR

  • Lists a number of classifications of Mental Health Disorders to include: Neurodevelopmental, Schizophrenia Spectrum, Bipolar & Related/Depressive, Anxiety/Obsessive-Compulsive, Trauma & Stressor Related
  • Others include Dissociative/Somatic Symptom, Feeding & Eating/Elimination/Sleep-Wake, Sexual Dysfunctions/Gender Dysphoria, Disruptive/Impulse-Control & Conduct, Substance Related & Addictive, Neurocognitive, Personality/Paraphilic and Medication Induced.

Psychotherapeutic Management

  • The therapeutic nurse-patient relationship, milieu management, and psychopharmacology are interdependent components of the psychotherapeutic management model.
  • Nurses manage the therapeutic community 24 hours a day.
  • The nurse is responsible for ensuring the patient's physiological and psychological needs are met.
  • Psychiatric nurses perform medication administration, develop therapeutic nurse-patient relationships, set limits, and teach patients.

Hildegard Peplau

  • Nurses function as resource person, counselor, teacher, leader, technical expert, and surrogate assisting individuals in need of mental health services.

Nurse-Patient Relationships

  • A PMH nurse’s building of therapeutic relationships is demonstrably skillful
  • This may be a brief therapeutic or a collaborative relationship, differentiating from a social relationship

Establishing Therapeutic Relationships

  • Critical components include trust, congruence, empathy, acceptance, and positive regard.
  • "Therapeutic use of self” occurs when the nurse uses aspects of his or her personality, experience, values, feelings, intelligence, needs, coping skills, and perceptions to establish a beneficial relationship with patients.

Stages of Therapeutic Nurse-Patient Relationship

  • Orientation: Build trust, ask permission, assess, manage emotions, set agenda, provide support & structure.
  • Working: In-depth data collection, reality testing, cognitive restructuring, writing and journaling, supportive confrontation, promote change, teach new skills.
  • Termination: Evaluate goal attainment and summarize progress.

BATHE Technique

  • The BATHE technique is a good communication technique for nursing students.
  • It is used in brief encounters and a focused interview technique.
  • BATHE helps the patient identify problems and coping strategies, and is supportive of the patient, however is not for suicidal patients.
  • BATHE stands for background, affect, trouble, handling, and empathy.
  • Some example questions are: What is going on/brought you here, How does this make you feel, what troubles you most in your situation, how are you able to handle this situation
  • The interviewer shows the patient they understand their view of the situation by empathizing with them.

Milieu Therapy

  • Scientific structuring of the environment is done in order to effect behavioral changes and improve the psychological health and functioning of the individual
  • Within the therapeutic community, the patient is expected to learn adaptive coping, appropriate interaction and relationship skills that can be applied to other aspects of their life

Basic Milieu Assumptions

  • The health in each individual is to be recognized and encouraged to grow
  • Every interaction is an opportunity for therapeutic intervention
  • The patient owns their own environment
  • Each patient owns their own behavior
  • Peer pressure is a useful and powerful tool
  • Inappropriate behavior is dealt with as it occurs
  • Restrictions and punishment are to be avoided

Interdisciplinary Team

  • A multi-disciplinary team consists of psychiatrists, clinical psychologists, psychiatric registered nurses, clinical nurse specialists, licensed vocational nurses, psychiatric technicians, psychiatric social workers
  • Case managers, mental health technicians, hospital assistants, therapists in art, recreation, psychodrama, music & occupational fields.
  • Additional members include dietitians and chaplains.

Modalities of Treatment

  • These include individual, couples or family therapy.
  • Group therapy is also used, including task groups, educational groups, self-help groups and supportive/therapeutic groups.
  • A task group accomplishes a specific outcome
  • An educational group conveys knowledge and information.
  • A self-help group is composed of individuals with similar issues with rotating leadership roles
  • Supportive/Therapeutic groups can involve group therapy, which are based on theory with an advanced degree clinician (autocratic, democratic, or laissez-faire leadership).
  • Therapeutic groups have less theory so they can focus on group relations and select issues for interaction of group members.
  • Important parts are the group process (how members interact with each other) And the group content (topic or issue discussed in the group).

Interventions in Groups

  • A group is a collection of individuals whose association is founded on shared commonalities of interest, values, norms or purpose.
  • Functions include socialization, support, task completion, camaraderie, informational, normative, empowerment and governance.

Safety Issues in the Milieu

  • Ensuring safety is a key role for the Registered Nurse.
  • This includes monitoring patients, movements and activities with safety as the foremost goal
  • Nurses are responsible for assessing psychodynamic issues and evaluating effectiveness of treatment and medications for individual patients, as well as the art of delegation.

Medication Administration

  • Informed consent is mandatory and driven by state law.
  • Informed consent must be signed and dated by the patient, doctor and a witness.
  • Consent must identify medication, maximum dosages, intended benefits and potential risks.
  • Medications that require informed consent are: psychotropics, antidepressants, antimanics, stimulants, and anxiolytics.
  • Documented medication consent is required prior to administrations.
  • If there is no consent, a dilemma arises between the necessity of the medication, legal ramifications, and the act of holding the dose; patient issues, courts etc may provide consent.

Psychopharmacology

  • There are general considerations to guide the use of medications, including the effect on target symptoms, adequate dosage for sufficient time, and lowest dose for maintenance.
  • Medications should be tapered, rather than abruptly ceased, to avoid rebound/withdrawal
  • Always follow up with primary physician
  • Neurotransmitters such as Acetylcholine, Dopamine, GABA, Norepinephrine and Serotonin are critical to conceptualize pathology and treatment of diseases.
  • Decreased intestinal motility and blood flow cause decreased absorption in the elderly.
  • Decreased body water, increased body fat, decreased plasma proteins and decreased lean body mass cause decreased distribution in the elderly.
  • Metabolism in the elderly is decreased due to decreased blood flow to the liver and decreased liver function.
  • Excretion in the elderly decrease due to diminished kidney function and decreased creatinine clearance.

Psychotropics in the Elderly

  • Start low and go slow
  • Neuroleptics can cause lower BP, confusion, dry mouth, constipation, urinary retention or TD.
  • Tricyclic Antidepressants can aggravate glaucoma, and cause urinary retention, hypotension, sedation, cardiotoxicity
  • Benzodiazepines can cause daytime sleepiness, confusion, fall risk, and be addictive, so avoid if possible.

Schizophrenia and Other Psychoactive Disorders

  • Schizophrenia characterizes a major psychotic disorder with disturbances in Perception, Thought processes, Reality testing, Feeling, Behavior, Attention, Motivation

Treatment for Schizophrenia

  • Use typical antipsychotics to target positive symptoms (hallucinations, delusions, disorganized thinking & behavior); but note the higher incidence of side effects.
  • Treat acute psychotic episodes with high potency neuroleptics such as Haloperidol (Haldol).
  • Haloperidol and Fluphenazine (Prolixin) are available in sesame oil based depot form (IM lasts 30 days).
  • Examples of typical antipsychotics include: Chlorpromazine (Thorazine), Thioridazine (Mellaril), Fluphenazine (Prolixin), Trifluoperazine (Stelazine), Haloperidol (Haldol), Chlorprothixene (Taractan), Thiothixene (Navane), Dibenzoxazepine (Loxapine), and Dihydroindolone (Moban).
  • Atypical Antipsychotics: can treat both the positive and negative symptoms of schizophrenia.
  • These do not exhibit as severe a side effect profile but new side effects can include Weight gain and New onset of diabetes.
  • Atypical Antipsychotic Med Examples: Aripiprazole (Abilify), Clozapine (Clozaril), Lurasidone (Latuda ), Olanzapine (Zyprexa), Paliperidone (Invega), Quetiapine (Seroquel), Risperidone (Risperdal), Ziprasidone (Geodon).

Clozapine (Clozaril)

  • This is a last option med used for refractory psychosis and is an expensive treatment option.
  • Patients trialed on this med have previously failed many antipsychotic trials.
  • Adverse side effects include orthostasis, sedation, weight gain, lower seizure threshold, sialorrhea, myocarditis and enuresis
  • Agranulocytosis/bone marrow suppression are likely, so monitor CBC and WBC.

Antiparkinson Medication

  • Extrapyramidal symptoms (EPS) that are adverse side effects from antipsychotic medication are caused by an imbalance between acetylcholine and dopamine.
  • EPS is caused by a blockade of dopamine receptors in the basal ganglia at the end of the dopamine tracts in an effort to decrease psychotic symptoms.
  • Anticholinergic drugs treat extrapyramidal symptoms and work to restore the balance between dopamine and acetylcholine.
  • Examples are Benztropine (Cogentin), Trihexyphenidyl (Artane), Diphenhydramine (Benadryl).
  • Side effects of anticholinergics can cause dry mouth, nasal congestion, urinary hesitation/retention, blurred vision, constipation, mydriasis.
  • Nursing interventions should be to provide sugarless candy/gum and water for dry mouth, nasal decongestant, warm water for urinary issues, sunglasses for light sensitivity, and diet/roughage for constipation.
  • Monitor for eye pain, and temperature regulation issues.
  • Other side effects and nursing interventions for anticholinergics include caution regarding orthostatic hypotension and sedation.
  • Monitor temperature and provide sponge bath for decreased sweating.
  • Loose fitting clothing can help control temperature.
  • Extrapyramidal Side Effects (EPS): Negative side effects of antipsychotic medication that occur in the basal ganglion of the brain
  • Symptoms include Acute dystonic reactions, Muscular rigidity, Pseudoparkinsonism, Akathisia, Akinesia, Tremors, Tardive dyskinesia (TD), Oculogyric crisis and Torticollis.

Tardive Dyskinesia (TD)

  • This is a nonreversable neurologic side effect that develops after long-term antipsychotic use
  • characterized by bizarre facial and tongue movements, stiff neck, and difficulty swallowing

Neuroleptic Malignant Syndrome (NMS)

  • This rare but potentially fatal complication of antipsychotic medication constitutes a medical emergency.
  • Monitor for Hyperthermia, Altered levels of consciousness, Severe muscle rigidity, Autonomic instability – tachycardia, Fluctuations in blood pressure, Elevated CPK's, Diaphoresis
  • Rapid deterioration of mental status, Rhabdomyolysis, Stupor, Coma and ultimately Death from this syndrome.
  • Monitor adverse side effects closely, especially 3-9 days after initiation of antipsychotic medication, and note elevated temperature.
  • Transfer to medicine for Inpatient psych transfer and use Dantrolene and Bromocriptine to treat.
  • Restart antipsychotics after a two week “wash out” period.

Anti-Depressants

  • Used to treat major depression, panic disorder, anxiety disorders, bipolar depression and psychotic depression

Selective Serotonin Reuptake Inhibitors (SSRI’s)

  • These are first-line agents with the fewest side effects, but can cause anxiety, agitation, akathisia, nausea, insomnia and sexual dysfunction.
  • Examples are Fluoxetine (Prozac), Fluvoxamine (Luvox), Paroxetine (Paxil), Sertraline (Zoloft) and Citalopram (Celexa).

Tricyclic and Tetracyclic Antidepressants (TCA’s)

  • These are second line agents that block reuptake of norepinephrine and serotonin.
  • They are associated with anticholinergic side effects, sedation, weight gain, tachycardia and sexual dysfunction.
  • Amitriptyline (Elavil) is a Tricyclic Antidepressant.

TCA Overdose

  • Nursing interventions include monitoring BP, HR & rhythm and RR, maintain patent airway and cardiac monitoring
  • Physostigmine (Antilirium) is used as an antidote for TCA poisoning.

Monoamine Oxidase Inhibitors MAOI’s

  • These are third line agents with side effects of daytime sedation, insomnia, weight gain, dry mouth, orthostatic hypotension, and require diet adherence to be effective.
  • Restrict tyramine in the diet (beer, wine, aged foods)
  • Maintain moderation in Chocolate and caffeine.
  • Avoid OTC cold medicine and diet pills to prevent hypertensive crisis.
  • Inform patients that a therapeutic effect should be achieved in 2-4 weeks.
  • Caution about driving if drowsy, check with doctors before mixing OTC medications and avoid high-tyramine foods.
  • Action in hypertensive crisis is to discontinue MAOI, administer Phenotolamine and monitor VS.

Novel Antidepressants

  • Selective Serotonin Reuptake Inhibitors SSRI's and Novel Antidepressants are the first line agents to treat depression.
  • Examples of Novel Antidepressants include: Bupropion (Wellbutrin, Zyban), Mirtazapine (Remeron), Nefazodone (Serzone), Trazodone (Desyrel) and Venlafaxine (Effexor).
  • Monitor for suicidal potential in these treatment medications. Prescriptions are provided with limited refills.

Serotonin Syndrome

  • Results from drug/drug interaction: SSRI & MAOI's, tryptophan, St. John's Wort
  • Symptoms include mental status changes, restlessness, agitation, myoclonus, hyperreflexia, diaphoresis, shivering or chills, tremors, Diarrhea, abdominal cramps & nausea, ataxia or incoordination and headache.

Mood Stabilizers

  • Antimanics treat Bipolar Disorders by addressing the whole spectrum.

Antimanic Agents

  • These include Lithium, Carbamazepine, Valproic Acid, Olanzapine, Aripiprazole.
  • Lithium therapeutic range is 0.6-1.2 mEq/L
  • Lithium side effects include: Fatigue, headache, impaired memory, ECG changes, bloating, weight gain, nausea, dry mouth, metallic taste, edema of hands & ankles, diarrhea, abdominal pain, thirst, mild hand tremors, acne, pruritus, polyuria, polydipsia, seizures and arrhythmias.
  • Monitor thyroid function and instruct patients on how to maintain adequate hydration and electrolyte balance.
  • Lithium toxicity presents at 1.5 mEq/L with diarrhea, vomiting, drowsiness, muscular weakness, ataxia.
  • Lithium Toxicity at 2.0-3.0 mEq/L presents moderate ataxia, giddiness, tinnitus, blurred vision, large output of dilute urine.
  • Lithium Toxcity at >3.0 mEq/L multiple leads to Organisms and organism systems involved, coma and death.
  • Intervention with 1.5-3.0 mEq/L is to hold the medication and administer supportive care.

Treatments for Lithium Toxity

  • There is no antidote.
  • For Severe Li+ poisoning, forced diuresis or hemodialysis is done.
  • Valproic Acid (Depakote) stabilizes mood by working on increasing GABA, increasing resting membrane potential and suppressing calcium with therapeutic levels between 50-100 ug/ml.
  • Side effects include Transient hair loss, weight gain, tremors, GU upset, thrombocytopenia.
  • Effective for patients who have no Li+ or depakote response, Carbamazepine controls normalizes sodium-channel activity with Therapeutic serum level: 8-12ug/ml but presents side effects.

Other Drugs to Treat Bipolar Disorder

  • Clonazepam (Klonopin), Lorazepam (Ativan), Clozapine (Clozaril), Risperidone, Quetiapine (Seroquel), Gabapentin (Neurontin), Lamotrigine and Topiramate.

Anxiety Drugs

  • Anxiolytics are used in the treatment of Generalized Anxiety Disorder, OCD, Panic Disorder, PTSD, Phobic Disorders and Insomnia
  • Benzodiazepines treat time limited crisis by enhancing GABA response to stressors to depress the central nervous system
  • They are psychologically and physiologically addictive and side effects include over-sedation, memory impairment, paradoxical excitement, emotional blunting, CNS depression, drowsiness, fatigue, ataxia and mental impairment.
  • Mixing benzos with CNS depressants can be lethal.
  • They are used as Anxiolytics, Hypnotics, Muscle relaxants, Anticonvulsants and Amnesics.
  • Examples are Alprazolam (Xanax), Chlordiazepoxide (Librium), Clonazepam (Klonopin), Clorazepate (Tranxene), Diazepam (Valium), Lorazepam (Ativan) and Oxazepam (Serax).
  • For overdose, look for Somnolence, Confusion, Coma, Diminished reflexes and Hypotension, and treat with gastric lavage, activated charcoal and monitor.
  • Physostigmine Is the antidote to diazepam poisoning while Flumazenil blocks Benzo's sites on gaba receptors and speed metabolism.

Anxiety: Other Treatment

  • Benzodiazepines can lead to overdose somnolence, confusion and reduced reflexes, which necessitate induced vomiting/lavage.
  • Long-acting Benzos such as Diazepam are contraindicated in the elderly.
  • Other Anti-Anxiety Agents Propranolol, Clomipramine, Imipramine, SSRI's (Prozac, Luvox, Paxil and Zoloft) and Venlafaxine are used as well.
  • The date rape drug Flunitrazepam renders an Amnesic effect.

Buspirone (Buspar)

  • This Nonbenzodiazepine treats anxiety by relaxing within 1-6 weeks with no known withdrawal and little interaction.
  • In the elderly, Lorazepam and Oxazepam are preferred and Temazepam and Alprazolam may be used.
  • Herbl such as kava and valerian cause an addictive effect, and to avoid overdose and driving while unsafe.
  • Benzos are not to be used to resolve minor/everyday stress, and may be unsafe combined with with alcohol/ cns depressants.

Dementia of the Alzheimer’s Type

  • Medications such as Tacrine, Donepezil, Galantamine treat mild to moderate forms of Alzheimer’s.
  • Memantine treat moderate to severe types of Alzheimer’s.
  • The focus of psychiatric management is the appreciation of current practices and implementation of nurse:patient relationship, Milieu management and Medication protocol.

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