Understanding Muscle and NMJ Lesions

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15 Questions

Which of the following is a 'positive' clinical manifestation of muscle disorders?

Cramps

What is the most common 'negative' symptom reported by a patient with muscle disease?

Weakness

Which of the following is a muscle disease commonly associated with myalgias?

Inflammatory myopathies

What is the primary meaning of 'myopathy'?

Suffering from muscle disease

Which type of muscle disease results in continuous, involuntary, painful, and localized muscle contractions?

Muscle cramps

What is the objective loss of power or strength resulting from pathology along the motor pathway called?

Weakness

Which of the following is an example of a known cause for muscle myotonia?

Dehydration

What is the common symptom associated with exercise intolerance?

Muscle pain

Which type of muscular hypertrophy refers to an increase in muscle glycogen storage?

Sarcoplasmic increase

What is the common cause of Duchene muscular dystrophy (DMD)?

Absence of dystrophin gene

Which gene mutation causes Myotonic Dystrophy type 1 (DM1)?

DMPK gene

What is the most common kind of muscular dystrophy in adults?

Myotonic dystrophy (MD)

What is the phenomenon of impaired relaxation of muscle after forceful voluntary contraction called?

Myotonia

What is the primary symptom of exercise intolerance?

Fatigue

What causes progressive muscle weakness and degeneration in Duchene muscular dystrophy (DMD)?

Absence of dystrophin gene

This quiz covers the definition, types, diagnosis, and treatment of myopathy and neuromuscular junction (NMJ) lesions. It includes important information about myopathy as a group of disorders primarily affecting skeletal muscle structure, metabolism, or ion channel function.

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