Understanding Haemolytic Anaemias
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Questions and Answers

Which type of thalassemia is characterized by impaired production of the β-chain due to mutation of one gene?

  • Beta thalassemia major
  • Beta thalassemia trait (correct)
  • Alpha thalassemia
  • Beta thalassemia intermediate

At what age does the switch from γ to β chain synthesis occur in beta thalassemia?

  • 18-24 months
  • 6-12 months (correct)
  • At birth
  • 3-6 months

Which subtype of beta thalassemia is characterized by hgF > 75%?

  • -Thalassemia major (correct)
  • -Thalassemia intermedia
  • -Thalassemia intermediate
  • -Thalassemia trait

In which type of thalassemia are the disorders due to mutations that decrease the rate of synthesis of one of the two globin chains (α or β)?

<p>Alpha thalassemia (C)</p> Signup and view all the answers

What is the genetic background of β thalassemia, which may be roughly divided into subtypes according to genetic defect?

<p>Heterozygous (A)</p> Signup and view all the answers

What is the genetic background of beta thalassemia, which may be roughly divided into subtypes according to genetic defect?

<p>Impaired production of beta chain due to mutation of one gene (heterozygous or both genes homozygous) (C)</p> Signup and view all the answers

Which type of thalassemia is characterized by impaired production of the beta-chain due to mutation of one gene?

<p>Beta thalassemia (C)</p> Signup and view all the answers

At what age does the switch from gamma to beta chain synthesis occur in beta thalassemia?

<p>$6-12$ months (D)</p> Signup and view all the answers

In which type of thalassemia are the disorders due to mutations that decrease the rate of synthesis of one of the two globin chains (alpha or beta)?

<p>Beta thalassemia (A)</p> Signup and view all the answers

Which subtype of beta thalassemia is characterized by hgF $>$ 75%?

<p>-Thalassemia major (A)</p> Signup and view all the answers

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