Understanding Autoimmune Diseases

What happens in an autoimmune disease?

How do genetic variations in MHC genes contribute to autoimmune diseases?

What role do environmental factors play in triggering autoimmune responses?

In autoimmune diseases, what can dysfunction in regulatory T cells lead to?

What happens when the immune system fails to distinguish between foreign invaders and the body's own cells?

What initiates the activation of self-reactive T lymphocytes in autoimmune diseases?

______ is a condition in which the body's immune system mistakenly attacks its own tissues

The immune system identifies and targets foreign substances such as bacteria, viruses, and other pathogens to protect the body from ______

Dysfunction in the regulatory mechanisms of the immune system, including impaired function of regulatory T cells, can lead to an imbalance between pro-inflammatory and anti-inflammatory responses, contributing to the development of ______ diseases

Certain genetic variations in the major histocompatibility complex (MHC) genes can increase susceptibility to autoimmune diseases by influencing how the immune system recognises self and ______

Environmental factors such as viral infections can trigger autoimmune responses by causing tissue ______

In autoimmune diseases, the immune system fails to distinguish between foreign invaders and the body’s own cells, leading to ______, tissue damage, and dysfunction of affected organs or systems