Podcast
Questions and Answers
Which of the following is NOT a cause of antibiotic therapy failure?
Which of the following is NOT a cause of antibiotic therapy failure?
- Wrong dose regimen
- Suppressed host response (correct)
- Poor selection
- Unjustified therapy
What is the purpose of carrying out microbial diagnosis?
What is the purpose of carrying out microbial diagnosis?
- To measure sensitivity
- To determine resistance
- To identify the type of bacteria (correct)
- To ensure owner compliance
How is resistance determined using disk-diffusion method?
How is resistance determined using disk-diffusion method?
- By observing the color change of the disk
- By analyzing the genetic material of the bacteria
- By measuring the relative diameter of inhibition (correct)
- By counting the number of colonies
What are clinical breakpoints used for?
What are clinical breakpoints used for?
Which organization sets lab standards for antibiotic resistance testing in the US?
Which organization sets lab standards for antibiotic resistance testing in the US?
What is the MIC value used to define resistance in the example criteria?
What is the MIC value used to define resistance in the example criteria?
Which of the following is an example of intrinsic resistance?
Which of the following is an example of intrinsic resistance?
What is the major mechanism of resistance for β-Lactams?
What is the major mechanism of resistance for β-Lactams?
Which of the following is an example of acquired resistance?
Which of the following is an example of acquired resistance?
What is the role of methicillin in methicillin resistance?
What is the role of methicillin in methicillin resistance?
Which of the following is NOT a common resistance mechanism for β-Lactams?
Which of the following is NOT a common resistance mechanism for β-Lactams?
What is the purpose of efflux systems in bacteria?
What is the purpose of efflux systems in bacteria?
Which mechanism of resistance is associated with aminoglycosides?
Which mechanism of resistance is associated with aminoglycosides?
Which mechanism of resistance is associated with quinolones?
Which mechanism of resistance is associated with quinolones?
Which mechanism of resistance is associated with glycopeptides?
Which mechanism of resistance is associated with glycopeptides?
Which mechanism of resistance is associated with tetracyclines?
Which mechanism of resistance is associated with tetracyclines?
Which mechanism of resistance is associated with rifamycins?
Which mechanism of resistance is associated with rifamycins?
Which mechanism of resistance is associated with oxazolidinones?
Which mechanism of resistance is associated with oxazolidinones?
Which mechanism of resistance is associated with pleuromutilins?
Which mechanism of resistance is associated with pleuromutilins?
What is the region between MIC and MSC called?
What is the region between MIC and MSC called?
What is the purpose of measuring sensitivity in antibiotic resistance testing?
What is the purpose of measuring sensitivity in antibiotic resistance testing?
What is the main difference between disk-diffusion and MIC determination methods in antibiotic resistance testing?
What is the main difference between disk-diffusion and MIC determination methods in antibiotic resistance testing?
What are clinical breakpoints used for in antibiotic resistance testing?
What are clinical breakpoints used for in antibiotic resistance testing?
Which organization sets lab standards for antibiotic resistance testing in Europe?
Which organization sets lab standards for antibiotic resistance testing in Europe?
What is the major mechanism of resistance for β-Lactams?
What is the major mechanism of resistance for β-Lactams?
What is the MIC value used to define resistance in the example criteria?
What is the MIC value used to define resistance in the example criteria?
What is the major difference between intrinsic and acquired resistance?
What is the major difference between intrinsic and acquired resistance?
What is the main mechanism of acquired resistance by mutation and modification of the target?
What is the main mechanism of acquired resistance by mutation and modification of the target?
Which group of antibiotics inhibits cell-wall synthesis?
Which group of antibiotics inhibits cell-wall synthesis?
What is the major mechanism of resistance for β-Lactams?
What is the major mechanism of resistance for β-Lactams?
Which bacteria are generally resistant to cephalosporins?
Which bacteria are generally resistant to cephalosporins?
What is mecA in the context of methicillin resistance?
What is mecA in the context of methicillin resistance?
Which of the following antibiotics inhibits the formation of the 70S ribosomal complex?
Which of the following antibiotics inhibits the formation of the 70S ribosomal complex?
Which resistance mechanism is associated with mutations in the 23S rRNA genes and ribosomal proteins preventing binding to the target?
Which resistance mechanism is associated with mutations in the 23S rRNA genes and ribosomal proteins preventing binding to the target?
Which term is used to describe strains that are resistant to up to three clinical antimicrobial categories, but still have usable options?
Which term is used to describe strains that are resistant to up to three clinical antimicrobial categories, but still have usable options?
Which resistance mechanism is associated with altered cell wall peptides and efflux?
Which resistance mechanism is associated with altered cell wall peptides and efflux?
Which factor increases the risk of selection for resistance?
Which factor increases the risk of selection for resistance?
Which resistance mechanism is associated with enzymatic modification, efflux, and ribosomal mutations?
Which resistance mechanism is associated with enzymatic modification, efflux, and ribosomal mutations?
Which antibiotic inhibits transcription by targeting the RNA polymerase?
Which antibiotic inhibits transcription by targeting the RNA polymerase?
Which antibiotic should be administered using the highest possible doses to achieve concentration-dependent killing?
Which antibiotic should be administered using the highest possible doses to achieve concentration-dependent killing?
Which one of these is a cause of antibiotic therapy failure?
Which one of these is a cause of antibiotic therapy failure?
What is the purpose of conducting culture and antibiotic sensitivity testing?
What is the purpose of conducting culture and antibiotic sensitivity testing?
How is resistance determined using disk-diffusion method?
How is resistance determined using disk-diffusion method?
Which type of resistance occurs when a microorganism obtains the ability to resist the activity of a new drug?
Which type of resistance occurs when a microorganism obtains the ability to resist the activity of a new drug?
Which of the following is an example of intrinsic resistance?
Which of the following is an example of intrinsic resistance?
Which resistance mechanism is associated with alteration of the drug, alteration of the target site, and efflux systems?
Which resistance mechanism is associated with alteration of the drug, alteration of the target site, and efflux systems?
Which antibiotic inhibits cell-wall synthesis?
Which antibiotic inhibits cell-wall synthesis?
What is the purpose of good antibiotic stewardship?
What is the purpose of good antibiotic stewardship?
Which term is used to describe strains that are resistant to all antimicrobial agents listed?
Which term is used to describe strains that are resistant to all antimicrobial agents listed?
What is the region between MIC and MSC called?
What is the region between MIC and MSC called?
