Understanding Angina Pectoris
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Questions and Answers

What is the immediate effect on arterioles when Angiotensin II binds to the AT1-receptor?

  • Inhibition of renin release
  • Vascular smooth muscle contraction (correct)
  • Dilation of blood vessels
  • Decrease in blood flow

Which organ is responsible for the conversion of Angiotensinogen to Angiotensin I?

  • Liver (correct)
  • Heart
  • Kidneys
  • Lungs

What role does ACE play in the Renin-Angiotensin-Aldosterone System (RAAS)?

  • It releases noradrenaline
  • It binds to AT1-receptors
  • It converts Angiotensin I to Angiotensin II (correct)
  • It synthesizes Angiotensinogen

Which component decreases due to decreased renal perfusion pressure?

<p>Renal blood flow (A)</p> Signup and view all the answers

What is the resulting physiological change when vascular smooth muscle cells (VSMCs) contract?

<p>Increased total peripheral resistance (TPR) (B)</p> Signup and view all the answers

How does the amount of lipids in a lipoprotein affect its density?

<p>More lipids result in lower density. (B)</p> Signup and view all the answers

What role does protein content play in the classification of lipoproteins?

<p>Higher protein content leads to higher density. (D)</p> Signup and view all the answers

What is the primary basis for the classification of lipoproteins?

<p>The density determined by ultracentrifugation. (A)</p> Signup and view all the answers

Which class of anti-hyperlipidemic drugs is commonly referred to as statins?

<p>HMG-CoA Reductase Inhibitors (C)</p> Signup and view all the answers

Which of the following lipoproteins is categorized as IDL?

<p>βVLDL (B)</p> Signup and view all the answers

What is the main cause of angina pectoris?

<p>A build-up of fatty plaque in the coronary arteries (C)</p> Signup and view all the answers

What happens to the density of lipoproteins if both lipids and proteins increase equally?

<p>The effect on density cannot be determined. (A)</p> Signup and view all the answers

Which of the following drugs is NOT a type of fibrate?

<p>Alirocumab (D)</p> Signup and view all the answers

What can result from reduced oxygenated blood flow to the cardiac muscle?

<p>Ischemia (D)</p> Signup and view all the answers

Which class of anti-hyperlipidemic drugs includes agents like ezetimibe?

<p>Ezetimibe class (A)</p> Signup and view all the answers

What is the overall aim of treating hypertension?

<p>To decrease arterial blood pressure (A)</p> Signup and view all the answers

Which of the following classes of anti-hypertensive drugs includes diltiazem and amlodipine?

<p>Calcium Channel Blockers (A)</p> Signup and view all the answers

Which substance is primarily responsible for transporting lipids in the bloodstream?

<p>Lipoproteins (A)</p> Signup and view all the answers

What is the effect of vascular smooth muscle cell (VSMC) hypertrophy and hyperplasia?

<p>Increased total peripheral resistance (A)</p> Signup and view all the answers

What do ACE inhibitors do in the treatment of hypertension?

<p>Inhibit angiotensin II production (A)</p> Signup and view all the answers

Which lipid component is found in the central core of lipoproteins?

<p>Both B and C (B)</p> Signup and view all the answers

Which medication class includes drugs like captopril and lisinopril?

<p>ACE Inhibitors (C)</p> Signup and view all the answers

What type of medication is losartan considered?

<p>Angiotensin II Type 1 (AT1) Receptor Antagonist (B)</p> Signup and view all the answers

What is the primary role of HDL in the body?

<p>Remove excess cholesterol from cells (D)</p> Signup and view all the answers

Which lipoprotein is primarily involved in the endogenous pathway of lipid transport?

<p>VLDL (B)</p> Signup and view all the answers

What does the enzyme HMG-CoA reductase primarily regulate?

<p>Cholesterol synthesis (A)</p> Signup and view all the answers

What is the primary therapeutic aim in treating patients with hyperlipidemia?

<p>Decrease LDL particles in the blood (C)</p> Signup and view all the answers

Which of the following lipoproteins does NOT contribute to the transportation of dietary lipids?

<p>IDL (A)</p> Signup and view all the answers

What are the remnants of chylomicrons primarily composed of after lipid transport?

<p>Triglycerides and cholesterol (C)</p> Signup and view all the answers

What is a potential consequence of excessive cholesterol uptake by peripheral tissues?

<p>Promoting atherosclerosis (C)</p> Signup and view all the answers

Which lipoprotein is most likely to increase in response to lipid deprivation in peripheral tissues?

<p>VLDL (D)</p> Signup and view all the answers

What role do bile acids play in lipid metabolism?

<p>Aid in dietary lipid absorption (B)</p> Signup and view all the answers

What is the function of lipoprotein lipase in lipid metabolism?

<p>Hydrolyzes triglycerides and releases free fatty acids (D)</p> Signup and view all the answers

Study Notes

Angina Pectoris

  • Angina pectoris is the medical term for acute chest pain, often caused by atherosclerosis.
  • Atherosclerosis is the narrowing of coronary arteries due to a build-up of fatty plaque.
  • The build-up of plaque in coronary arteries leads to decreased oxygenated blood and nutrient supply to the cardiac muscle.
  • Decreased oxygenated blood and nutrient supply to the cardiac muscle causes ischemia, a condition that leads to angina pectoris.

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Description

This quiz explores angina pectoris, a condition characterized by acute chest pain often resulting from atherosclerosis. Learn about the mechanisms behind the narrowing of coronary arteries and its impacts on heart health. Test your knowledge on prevention and management of this condition.

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