Undergraduate Medicine Year 2: Enteric Infections

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Questions and Answers

What is the primary method of treatment for gastroenteritis?

  • Rest and diet modification
  • Intravenous medication
  • Rehydration (correct)
  • Antibiotics for all patients

When are antibiotics indicated for patients with gastroenteritis?

  • If symptoms last more than 48 hours
  • If they are bacteraemic or immunosuppressed (correct)
  • Always for all patients
  • Only if they have a fever

Which antibiotic may be used if indicated for gastroenteritis?

  • Metronidazole
  • Amoxicillin
  • Ciprofloxacin (correct)
  • Penicillin

What is one of the recommended practices for preventing gastroenteritis?

<p>Good food hygiene practices (D)</p> Signup and view all the answers

Which of the following is NOT a part of the treatment protocol for gastroenteritis?

<p>Antibiotics for everyone (D)</p> Signup and view all the answers

Which organism is primarily associated with giardiasis?

<p>Giardia lamblia (B)</p> Signup and view all the answers

Which of the following pathogens is commonly responsible for amoebiasis?

<p>Entamoeba histolytica (B)</p> Signup and view all the answers

Which bacteria are categorized as non-typhoidal Salmonella?

<p>Salmonella enteritidis (A), Salmonella bongori (D)</p> Signup and view all the answers

Which condition is NOT caused by Vibrio species?

<p>Giardiasis (C)</p> Signup and view all the answers

Which of these pathogens is primarily associated with foodborne illnesses?

<p>Listeria spp (B)</p> Signup and view all the answers

What is the primary diagnostic method for enterohaemorrhagic E. coli?

<p>PCR (faeces) (C)</p> Signup and view all the answers

Why are antibiotics not recommended for treating enterohaemorrhagic E. coli infections?

<p>They lead to increased toxin release. (B)</p> Signup and view all the answers

What is one of the key management practices for patients with enterohaemorrhagic E. coli?

<p>Rehydration (B)</p> Signup and view all the answers

In managing enterohaemorrhagic E. coli, what isolation measures are suggested?

<p>Isolation in hospital with contact precautions (D)</p> Signup and view all the answers

Which of the following is true regarding the culture method for diagnosing enterohaemorrhagic E. coli?

<p>Culture in a reference lab is necessary to confirm. (B)</p> Signup and view all the answers

What is the primary symptom of enterotoxigenic E. coli infection?

<p>Watery (non-bloody) diarrhoea (C)</p> Signup and view all the answers

What is the primary cause of gastroenteritis?

<p>Contaminated food or drink (C)</p> Signup and view all the answers

Which of the following is NOT a recognized complication of food poisoning?

<p>Psychosis (C)</p> Signup and view all the answers

In which regions is enterotoxigenic E. coli most commonly found?

<p>Underdeveloped countries or regions with poor sanitation (C)</p> Signup and view all the answers

What is the typical duration for the symptoms of an enterotoxigenic E. coli infection?

<p>1-5 days (A)</p> Signup and view all the answers

What is the minimum frequency of loose or liquid stools required to define diarrhea?

<p>3 times in 24 hours (B)</p> Signup and view all the answers

Which of the following is a key virulence factor in foodborne pathogens?

<p>Toxin production (A)</p> Signup and view all the answers

Which of the following best describes the severity of the symptoms caused by enterotoxigenic E. coli?

<p>Can range from minor discomfort to severe cholera-like syndrome (C)</p> Signup and view all the answers

What is the incubation period for enterotoxigenic E. coli infection?

<p>1-3 days (C)</p> Signup and view all the answers

How are most cases of food poisoning transmitted?

<p>Contaminated food/water (B)</p> Signup and view all the answers

Which factor is NOT typically associated with food poisoning outbreaks?

<p>Mild stress levels (B)</p> Signup and view all the answers

What is one common symptom of food poisoning?

<p>Nausea (A)</p> Signup and view all the answers

What type of illness can food poisoning result in besides gastroenteritis?

<p>Neurological syndromes (D)</p> Signup and view all the answers

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Study Notes

Learning Outcomes

  • Understand the epidemiology of key foodborne pathogens.
  • Identify virulence factors of foodborne pathogens and their roles in infection.
  • Describe the pathogenesis of food poisoning.
  • Recognize clinical features and complications associated with food poisoning.
  • Outline laboratory diagnosis techniques for food poisoning.
  • Select appropriate management strategies for patients experiencing food poisoning.
  • Implement measures to prevent foodborne illnesses.

Definitions

  • Gastritis: Inflammation of the stomach lining.
  • Gastroenteritis: Inflammation of the stomach and intestinal lining, often caused by food poisoning or irritants.
  • Food Poisoning: Illnesses resulting from ingesting contaminated food causing gastrointestinal issues, systemic illness, or neurological syndromes.
  • Diarrhoea: Defined as three or more loose or liquid stools within 24 hours for an extended period (more than three days).

Food Poisoning Epidemiology

  • Common and caused by various infectious agents; often sporadic with potential outbreaks.
  • Reporting to Public Health agencies required; details available on HPSC website.
  • Transmission typically occurs via contaminated food/water; implicated pathogens include:
    • Non-typhoidal Salmonella
    • Shigella spp.
    • Vibrio spp.
    • Yersinia spp.
    • Listeria spp.
    • Protozoa such as Giardia lamblia and Entamoeba histolytica.

Lecture Focus

  • Diagnosis through PCR and culture of faeces or blood is essential for determining food poisoning causes.

Treatment

  • Rehydration is critical for all cases.
  • Antibiotics are not routinely prescribed for gastroenteritis unless the patient is bacteremic or immunosuppressed, with azithromycin or ciprofloxacin used if susceptible.
  • Preventative measures rely on good food hygiene practices, including proper cooking/storage of meat and thorough handwashing after contact with animals or raw meat.

Specific Pathogens

  • Enterohaemorrhagic E. coli:

    • Diagnosis via PCR of faeces; culture confirmation needed from reference labs.
    • Management focuses on rehydration; antibiotics can exacerbate symptoms due to toxin release.
    • Hospitalization may be necessary for isolated cases with contact precautions.
  • Enterotoxigenic E. coli (Traveler's Diarrhoea):

    • Common in underdeveloped regions with poor sanitation.
    • Short incubation period (1-3 days), presenting with watery diarrhoea, fever, and nausea.
    • Symptoms can range from mild discomfort to severe cholera-like syndrome; usually self-limiting within 1-5 days.

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