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Viral purification and concentration

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Questions and Answers

What is the primary role of ultracentrifuges in virology?

To increase the temperature of viral cultures

To enhance viral replication

To concentrate and purify viruses (correct)

To destroy viral particles

Why are ultracentrifuges particularly useful for studying viruses

They can sediment even the smallest viruses (correct)

They allow viruses to multiply rapidly

They prevent viral contamination

They reduce the infectivity of viruses

What is the main principle behind rate-zonal centrifugation?

Particles are separated based on their buoyant density

Particles move at different rates depending on their mass (correct)

Particles aggregate at the bottom of the centrifuge tube

Particles are destroyed through high-speed spinning

Which type of centrifugation separates particles solely based on their buoyant density?

Isopycnic (equilibrium) centrifugation Signup and view all the answers

Another term for isopycnic centrifugation is

Density gradient separation Signup and view all the answers

In rate-zonal centrifugation, what determines how fast a particle moves through the medium?

Its mass Signup and view all the answers