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Types of Tissue Engineered Skin and Skin Substitutes Classification

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Types of Tissue Engineered Skin and Skin Substitutes Classification

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Questions and Answers

Which type of tissue engineered skin contains only dermal components?

Epidermal skin substitute

Cultured epidermal cells with no dermal components

Dermal skin substitute (correct)

A bilayer containing both dermal and epidermal components

What is the classification of skin substitutes based on the type of biomaterial used?

Permanent, semipermanent, or temporary

Epidermal, dermal, or dermo-epidermal

Biological (autologous, allogeneic, xenogeneic) or Synthetic (biodegradable, non-biodegradable) (correct)

Cellular or acellular

Why can none of the three types of tissue engineered skin fully simulate native skin?

They lack dermal components

They are not classified correctly

They lack both dermal and epidermal components (correct)

They lack epidermal components

What are the essential characteristics that the ideal tissue-engineered skin substitute must possess?

Biomechanical properties and barrier function Signup and view all the answers

Which of the following is NOT a requirement for the design and development of an ideal skin substitute?

Inflammatory reactions and toxicity Signup and view all the answers

What is the primary function of establishing a mechanical barrier in a bioengineered skin substitute?

To restrict fluid loss, wound colonization, and vapor transit Signup and view all the answers

Which skin substitute consists of dermal and epidermal layers?

OrCel® Ortec International Inc., USA Signup and view all the answers

What material is the TissueTech Autograft System made of?

Polyethylene oxide terephthalate (PEO)/polybutylene terephthalate (PBT) Signup and view all the answers

Which skin substitute is a sprayed suspension of allogeneic keratinocytes and fibroblasts on a fibrin substrate?

Allox DFB Pharmaceuticals, Inc., USA Signup and view all the answers

Which skin substitute is composed of intact matrix from porcine small-intestine submucosa for wound closure stimulation?

Oasis® Healthpoint Biotherapeutics, USA Signup and view all the answers