Types of Study Designs in Research
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Questions and Answers

What is the purpose of the intensive behavioral modification program mentioned in the text?

  • To reduce total fat intake and increase fruit consumption (correct)
  • To increase total fat intake and reduce fruit consumption
  • To encourage participants to skip meals
  • To maintain the current dietary habits of the participants
  • In the context of the study, why is randomization considered the 'gold standard' for estimating causal effects?

  • It allows for the comparison of outcomes between different age groups
  • It ensures that the control group will experience the same outcomes as the treatment group
  • It eliminates any potential bias in selecting subjects for the study (correct)
  • It guarantees that all participants will adhere to the assigned treatment or intervention
  • What does 'blocked randomization' aim to address in the context of clinical trials?

  • Imbalance in the distribution of participants' characteristics between treatment and control groups (correct)
  • Imbalance in the representation of different geographic locations in the study
  • Imbalance in the allocation of subjects to different age groups
  • Imbalance in the observed incidence of outcomes among subjects in the control group
  • What characteristic makes simple randomization easy to implement?

    <p>It involves straightforward methods like coin flips or choosing cards from a hat</p> Signup and view all the answers

    What is suggested by the statement 'Characteristics appear to be well-balanced between intervention and comparison groups' in the text?

    <p>Unknown factors should also be balanced between the groups</p> Signup and view all the answers

    What does the text imply about the possibility of imbalance in small trials even with simple randomization?

    <p>It can still occur despite using simple randomization</p> Signup and view all the answers

    What is the distinguishing feature of experimental studies in the context of randomized controlled trials?

    <p>Investigator assigns treatment status</p> Signup and view all the answers

    In the context of RCTs, what type of study involves the investigator observing the relationship between treatment and outcome without assigning the treatment?

    <p>Cohort studies</p> Signup and view all the answers

    What is the term for 'almost' experiments which lack randomization in the context of RCTs?

    <p>Quasi-experimental studies</p> Signup and view all the answers

    What term describes the determinant or cause of outcome being distributed unequally across exposure groups in the context of RCTs?

    <p>Confounding</p> Signup and view all the answers

    What is the purpose of randomization in the context of RCTs?

    <p>To balance known and unknown confounders between treatment groups</p> Signup and view all the answers

    What characteristic makes simple randomization desirable in RCTs?

    <p>It tends to produce comparable groups on average</p> Signup and view all the answers

    In RCTs, what term describes the uncertainty about risks and benefits of treatment?

    <p>Equipoise</p> Signup and view all the answers

    In RCTs, what type of study involves the investigator assigning treatment status and is considered the 'gold standard' for estimating causal effects?

    <p>Experimental studies</p> Signup and view all the answers

    What does random assignment of intervention or treatment aim to achieve in RCTs?

    <p>To balance known and unknown confounders between treatment groups</p> Signup and view all the answers

    What characteristic makes quasi-experimental studies 'almost' experiments in RCTs?

    <p>Lack of randomization</p> Signup and view all the answers

    What characteristic distinguishes experimental studies in the context of randomized controlled trials (RCTs)?

    <p>Patients are randomly assigned to different exposure groups</p> Signup and view all the answers

    What term describes the uncertainty about risks and benefits of treatment in the context of RCTs?

    <p>Equipoise</p> Signup and view all the answers

    In RCTs, what type of study involves the investigator observing the relationship between treatment and outcome without assigning the treatment?

    <p>Cohort studies</p> Signup and view all the answers

    What does random assignment of intervention or treatment aim to achieve in RCTs?

    <p>Balancing known and unknown confounders between treatment groups</p> Signup and view all the answers

    What characteristic makes simple randomization desirable in RCTs?

    <p>It tends to produce comparable groups</p> Signup and view all the answers

    What is the purpose of randomization in the context of randomized controlled trials (RCTs)?

    <p>To create a balanced distribution of known and unknown factors between intervention and control groups</p> Signup and view all the answers

    What does 'blocked randomization' aim to address in the context of clinical trials?

    <p>It aims to address the possibility of imbalance, especially in small trials</p> Signup and view all the answers

    What is suggested by the statement 'Characteristics appear to be well-balanced between intervention and comparison groups' in the text?

    <p>The distribution of participant characteristics is similar between the two groups</p> Signup and view all the answers

    What is the distinguishing feature of experimental studies in the context of randomized controlled trials (RCTs)?

    <p>Both known and unknown factors are evenly distributed between treatment and control groups</p> Signup and view all the answers

    What characteristic makes simple randomization desirable in RCTs?

    <p>It allows for easy implementation using methods like coin flip or random number generators</p> Signup and view all the answers

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