Types of Study Designs in Research

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Questions and Answers

What is the purpose of the intensive behavioral modification program mentioned in the text?

  • To reduce total fat intake and increase fruit consumption (correct)
  • To increase total fat intake and reduce fruit consumption
  • To encourage participants to skip meals
  • To maintain the current dietary habits of the participants

In the context of the study, why is randomization considered the 'gold standard' for estimating causal effects?

  • It allows for the comparison of outcomes between different age groups
  • It ensures that the control group will experience the same outcomes as the treatment group
  • It eliminates any potential bias in selecting subjects for the study (correct)
  • It guarantees that all participants will adhere to the assigned treatment or intervention

What does 'blocked randomization' aim to address in the context of clinical trials?

  • Imbalance in the distribution of participants' characteristics between treatment and control groups (correct)
  • Imbalance in the representation of different geographic locations in the study
  • Imbalance in the allocation of subjects to different age groups
  • Imbalance in the observed incidence of outcomes among subjects in the control group

What characteristic makes simple randomization easy to implement?

<p>It involves straightforward methods like coin flips or choosing cards from a hat (A)</p> Signup and view all the answers

What is suggested by the statement 'Characteristics appear to be well-balanced between intervention and comparison groups' in the text?

<p>Unknown factors should also be balanced between the groups (A)</p> Signup and view all the answers

What does the text imply about the possibility of imbalance in small trials even with simple randomization?

<p>It can still occur despite using simple randomization (D)</p> Signup and view all the answers

What is the distinguishing feature of experimental studies in the context of randomized controlled trials?

<p>Investigator assigns treatment status (B)</p> Signup and view all the answers

In the context of RCTs, what type of study involves the investigator observing the relationship between treatment and outcome without assigning the treatment?

<p>Cohort studies (B)</p> Signup and view all the answers

What is the term for 'almost' experiments which lack randomization in the context of RCTs?

<p>Quasi-experimental studies (C)</p> Signup and view all the answers

What term describes the determinant or cause of outcome being distributed unequally across exposure groups in the context of RCTs?

<p>Confounding (A)</p> Signup and view all the answers

What is the purpose of randomization in the context of RCTs?

<p>To balance known and unknown confounders between treatment groups (C)</p> Signup and view all the answers

What characteristic makes simple randomization desirable in RCTs?

<p>It tends to produce comparable groups on average (D)</p> Signup and view all the answers

In RCTs, what term describes the uncertainty about risks and benefits of treatment?

<p>Equipoise (A)</p> Signup and view all the answers

In RCTs, what type of study involves the investigator assigning treatment status and is considered the 'gold standard' for estimating causal effects?

<p>Experimental studies (B)</p> Signup and view all the answers

What does random assignment of intervention or treatment aim to achieve in RCTs?

<p>To balance known and unknown confounders between treatment groups (B)</p> Signup and view all the answers

What characteristic makes quasi-experimental studies 'almost' experiments in RCTs?

<p>Lack of randomization (A)</p> Signup and view all the answers

What characteristic distinguishes experimental studies in the context of randomized controlled trials (RCTs)?

<p>Patients are randomly assigned to different exposure groups (A)</p> Signup and view all the answers

What term describes the uncertainty about risks and benefits of treatment in the context of RCTs?

<p>Equipoise (A)</p> Signup and view all the answers

In RCTs, what type of study involves the investigator observing the relationship between treatment and outcome without assigning the treatment?

<p>Cohort studies (D)</p> Signup and view all the answers

What does random assignment of intervention or treatment aim to achieve in RCTs?

<p>Balancing known and unknown confounders between treatment groups (B)</p> Signup and view all the answers

What characteristic makes simple randomization desirable in RCTs?

<p>It tends to produce comparable groups (C)</p> Signup and view all the answers

What is the purpose of randomization in the context of randomized controlled trials (RCTs)?

<p>To create a balanced distribution of known and unknown factors between intervention and control groups (D)</p> Signup and view all the answers

What does 'blocked randomization' aim to address in the context of clinical trials?

<p>It aims to address the possibility of imbalance, especially in small trials (D)</p> Signup and view all the answers

What is suggested by the statement 'Characteristics appear to be well-balanced between intervention and comparison groups' in the text?

<p>The distribution of participant characteristics is similar between the two groups (D)</p> Signup and view all the answers

What is the distinguishing feature of experimental studies in the context of randomized controlled trials (RCTs)?

<p>Both known and unknown factors are evenly distributed between treatment and control groups (C)</p> Signup and view all the answers

What characteristic makes simple randomization desirable in RCTs?

<p>It allows for easy implementation using methods like coin flip or random number generators (C)</p> Signup and view all the answers

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