Podcast
Questions and Answers
Which type of RNA carries genetic information from DNA to the ribosomes?
Which type of RNA carries genetic information from DNA to the ribosomes?
What is the main role of ribosomal RNA (rRNA)?
What is the main role of ribosomal RNA (rRNA)?
Which functional component is NOT associated with the 3' end of mRNA?
Which functional component is NOT associated with the 3' end of mRNA?
Which type of RNA is involved in RNA interference (RNAi)?
Which type of RNA is involved in RNA interference (RNAi)?
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What geometry does helical RNA typically adopt?
What geometry does helical RNA typically adopt?
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What is the role of transfer RNA (tRNA)?
What is the role of transfer RNA (tRNA)?
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Study Notes
Types of RNA Molecules
- There are several types of RNA molecules, including messenger RNAs (mRNAs), transfer RNAs (tRNAs), ribosomal RNAs (rRNAs), small interfering RNAs (siRNAs), long non-coding RNAs (long ncRNAs), microRNAs (miRNAs), and ribozymes.
- Each type of RNA molecule has a unique function in the process of gene expression.
Messenger RNA (mRNA)
- Carries genetic information from DNA to the ribosomes.
- Instructions for building a protein are carried by mRNA.
RNA Structure
- RNA is intrinsically single-stranded.
- The 2'-OH group prevents RNA from forming a B-form helix.
- RNA adopts an A-form geometry when helical.
- Major groove is deep and narrow, while minor groove is wide.
- Secondary structure is observed in rRNA and tRNA, and is assumed to be present in mRNA.
- The 3' end of mRNA is polyadenylated.
PolyA Tail
- The polyA tail is not coding and is added after transcription.
- It stabilizes mRNA and its removal leads to RNA degradation.
- The polyA tail also inhibits translation.
Ribosomal RNA (rRNA)
- rRNA is complex and makes up the ribosomes.
- Ribosomes are the "protein factories" and are large macromolecular assemblies.
- They are composed of many proteins and rRNA molecules.
Transfer RNA (tRNA)
- tRNA acts as an intermediary between the nucleic acid and protein worlds.
- It acts as a translator, carrying amino acids to the ribosomes during protein synthesis.
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Description
Learn about the different types of RNA molecules, including messenger RNA, transfer RNA, ribosomal RNA, and more!