Podcast
Questions and Answers
What is the primary function of ribosomal RNA (rRNA)?
What is the primary function of ribosomal RNA (rRNA)?
Transfer RNA (tRNA) carries the genetic information from the nucleus to the ribosome.
Transfer RNA (tRNA) carries the genetic information from the nucleus to the ribosome.
False
What is the role of the anticodon in transfer RNA (tRNA)?
What is the role of the anticodon in transfer RNA (tRNA)?
To base-pair with the complementary code on the mRNA molecule
The 3' end of tRNA is known as the _____ attachment site.
The 3' end of tRNA is known as the _____ attachment site.
Signup and view all the answers
Match the types of RNA with their functions:
Match the types of RNA with their functions:
Signup and view all the answers
Which of the following types of small RNA induces degradation of targeted mRNA?
Which of the following types of small RNA induces degradation of targeted mRNA?
Signup and view all the answers
Heterogeneous nuclear RNA (hnRNA) is considered premature mRNA.
Heterogeneous nuclear RNA (hnRNA) is considered premature mRNA.
Signup and view all the answers
What percentage of total cellular RNA is made up of Transfer RNA (tRNA)?
What percentage of total cellular RNA is made up of Transfer RNA (tRNA)?
Signup and view all the answers
What is the total number of rRNA strands present in the larger subunit of a ribosome?
What is the total number of rRNA strands present in the larger subunit of a ribosome?
Signup and view all the answers
Eukaryotic ribosomes are smaller than prokaryotic ribosomes.
Eukaryotic ribosomes are smaller than prokaryotic ribosomes.
Signup and view all the answers
What are the main nucleotide components of rRNA?
What are the main nucleotide components of rRNA?
Signup and view all the answers
The _____ site in a ribosome is where tRNA molecules attach during protein synthesis.
The _____ site in a ribosome is where tRNA molecules attach during protein synthesis.
Signup and view all the answers
Match the ribosome types to their size classification:
Match the ribosome types to their size classification:
Signup and view all the answers
Which of the following is NOT a feature of rRNA's secondary structure?
Which of the following is NOT a feature of rRNA's secondary structure?
Signup and view all the answers
Both prokaryotic and eukaryotic ribosomes contain rRNA and proteins.
Both prokaryotic and eukaryotic ribosomes contain rRNA and proteins.
Signup and view all the answers
What role do ribosomes play in the cell?
What role do ribosomes play in the cell?
Signup and view all the answers
What is the primary function of mRNA?
What is the primary function of mRNA?
Signup and view all the answers
MRNA is a double-stranded molecule.
MRNA is a double-stranded molecule.
Signup and view all the answers
What are the major bases found in mRNA?
What are the major bases found in mRNA?
Signup and view all the answers
Transcription is the process where mRNA is synthesized from __________.
Transcription is the process where mRNA is synthesized from __________.
Signup and view all the answers
Match the following characteristics of mRNA with their descriptions:
Match the following characteristics of mRNA with their descriptions:
Signup and view all the answers
What structural feature of mRNA stabilizes it and provides protection in the cytoplasm?
What structural feature of mRNA stabilizes it and provides protection in the cytoplasm?
Signup and view all the answers
Methylation typically occurs at the 5' terminal nucleoside of eukaryotic mRNAs.
Methylation typically occurs at the 5' terminal nucleoside of eukaryotic mRNAs.
Signup and view all the answers
What is a polyribosome?
What is a polyribosome?
Signup and view all the answers
What unique feature of tRNA helps protect it from dehydration when in the cytoplasm?
What unique feature of tRNA helps protect it from dehydration when in the cytoplasm?
Signup and view all the answers
TRNA consists solely of the usual nitrogenous bases: adenine, uracil, guanine, and cytosine.
TRNA consists solely of the usual nitrogenous bases: adenine, uracil, guanine, and cytosine.
Signup and view all the answers
What are the two main legs of tRNA's L-shaped tertiary structure called?
What are the two main legs of tRNA's L-shaped tertiary structure called?
Signup and view all the answers
TRNA binds to specific amino acids and transfers them to the ________ ends of growing peptide chains.
TRNA binds to specific amino acids and transfers them to the ________ ends of growing peptide chains.
Signup and view all the answers
Match the unusual base with its corresponding conventional base:
Match the unusual base with its corresponding conventional base:
Signup and view all the answers
What is the typical length of tRNA molecules?
What is the typical length of tRNA molecules?
Signup and view all the answers
Each tRNA molecule carries one Thymine (T) nucleotide.
Each tRNA molecule carries one Thymine (T) nucleotide.
Signup and view all the answers
What is formed when the $3^‘$-OH group of tRNA binds to the $eta$-COOH of a specific amino acid?
What is formed when the $3^‘$-OH group of tRNA binds to the $eta$-COOH of a specific amino acid?
Signup and view all the answers
The cloverleaf structure of tRNA is formed due to hydrogen bonding of complementary bases in different ______.
The cloverleaf structure of tRNA is formed due to hydrogen bonding of complementary bases in different ______.
Signup and view all the answers
Which of the following is NOT a minor base found in tRNA?
Which of the following is NOT a minor base found in tRNA?
Signup and view all the answers
Match the structures of tRNA with their descriptions:
Match the structures of tRNA with their descriptions:
Signup and view all the answers
The double helical stems of tRNA are typically in a B-DNA conformation.
The double helical stems of tRNA are typically in a B-DNA conformation.
Signup and view all the answers
What conformation do the double helical stems of tRNA resemble?
What conformation do the double helical stems of tRNA resemble?
Signup and view all the answers
What is the primary function of the 5' cap on eukaryotic mRNA?
What is the primary function of the 5' cap on eukaryotic mRNA?
Signup and view all the answers
Prokaryotic mRNA is typically monocistronic.
Prokaryotic mRNA is typically monocistronic.
Signup and view all the answers
What is the main component of the poly-A tail added to eukaryotic mRNA?
What is the main component of the poly-A tail added to eukaryotic mRNA?
Signup and view all the answers
The precursor of mRNA in mammalian nuclei is called ______.
The precursor of mRNA in mammalian nuclei is called ______.
Signup and view all the answers
Match the following types of RNA with their functions:
Match the following types of RNA with their functions:
Signup and view all the answers
How is the 5' cap connected to the 5' terminal nucleoside in eukaryotic mRNA?
How is the 5' cap connected to the 5' terminal nucleoside in eukaryotic mRNA?
Signup and view all the answers
75% of hnRNA is processed into mature mRNA in the nucleus.
75% of hnRNA is processed into mature mRNA in the nucleus.
Signup and view all the answers
What is the role of U1 snRNA in RNA processing?
What is the role of U1 snRNA in RNA processing?
Signup and view all the answers
Study Notes
Types of RNA
- In prokaryotic and eukaryotic organisms, three main classes of RNA molecules exist
- Messenger RNA (mRNA)
- Transfer RNA (t RNA)
- Ribosomal RNA (r RNA)
- Heterogeneous nuclear RNA (hnRNA)
- Small RNAs also exist:
- Small nuclear RNA (snRNA)
- Micro RNA (miRNA)
- Small interfering RNA (siRNA)
- Non-coding RNA (ncRNA)
Significance
- mRNA - Carries genetic formation of DNA for protein synthesis from nucleus to ribosome
- rRNA - Combines with proteins to form ribosomes
- tRNA - Acts as an adapter molecule. Carries amino acid and drops it on mRNA with its anticodon on mRNA
- snRNAs - part of spliceosomes - that edit mRNAs
tRNA Characteristics
- There are two ends in the tRNA:
- 5' end
- 3' end
- The 3' end is where the amino acid is attached and it is called the amino acid attachment site.
Transfer RNA (tRNA) or Soluble RNA (srRNA)
- Smaller than other RNAs (MW 18-28 KD)
- 10-20% of the total cellular RNA
- In cytosol and mitochondrial matrix
- Average animal cells carry around 56 tRNAs
- Named according to the specific amino acid they bind to and transfer, eg. phenylalanine mRNA (tRNAPhe)
mRNA Structure and Function
- tRNA, like mRNA, is made in the nucleus and is used over and over again.
- tRNA binds an amino acid at one end and has an anticodon at the other end.
- The anticodon acts to base pair with the complementary code on the mRNA molecule, and delivers an amino acid to the ribosome.
Studying That Suits You
Use AI to generate personalized quizzes and flashcards to suit your learning preferences.
Description
This quiz explores the various types of RNA, including mRNA, tRNA, and rRNA, along with their significance in protein synthesis and gene expression. Learn about the characteristics of transfer RNA and its essential roles in cellular functions. Test your knowledge on small RNAs and their contributions to the genetic processes!