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Types of Red Pulp in Mammalian Spleens

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Questions and Answers

What is the main function of the red pulp in the spleen?

Initiation of immune responses

Production of white blood cells

Storage of red blood cells (correct)

Production of red blood cells

Which component of the spleen is rich in lymphocytes and actively involved in immune responses?

Trabeculae

Red pulp

White pulp (correct)

Splenic cords

What type of tissue occupies the spaces between the trabeculae in the spleen?

Connective tissue

Splenic pulp (correct)

Fibrous tissue

Adipose tissue

Which cell type removes damaged erythrocytes from circulation in the spleen?

Macrophages Signup and view all the answers

What structures extend from the capsule and hilus into the splenic parenchyma?

Trabeculae Signup and view all the answers

Which layer of the spleen capsule consists of smooth muscle?

Inner layer Signup and view all the answers

What are the venous channels found in the red pulp of the spleen called?

Sinusoids Signup and view all the answers

What is the unique feature of the bursa of Fabricius in birds?

It is a saclike dorsal diverticulum of the proctodeum. Signup and view all the answers

What is the structure of the follicles within the bursa of Fabricius?

They contain numerous polyhedral lymphatic tissue follicles. Signup and view all the answers

What is the role of the bursa of Fabricius in B-cell differentiation?

It is functionally equivalent to the mammalian bone marrow. Signup and view all the answers

At what stage of chicken embryo development do precursor cells committed to the B-cell lineage migrate into the developing bursa of Fabricius?

Day 8 to day 15 of development. Signup and view all the answers

What is the process by which lymphatic nodules develop in the bursa of Fabricius?

They form as invaginations of the cloacal epithelium into underlying tissues. Signup and view all the answers

What is the significance of the dichotomy of T- and B-cell lineages first being revealed in birds?

It demonstrates the unique features of the avian immune system. Signup and view all the answers

What is the significance of the epithelial tuft of simple columnar cells covering the apex of each follicle in the bursa of Fabricius?

It is a specialized feature that is unique to the avian bursa of Fabricius. Signup and view all the answers

What is the function of the capillary layer separating the cortex and medulla of the follicles in the bursa of Fabricius?

It provides nutrients and oxygen to the lymphatic tissue. Signup and view all the answers

What is the significance of the pseudostratified columnar epithelium lining the bursa of Fabricius?

It provides structural support and protection for the underlying lymphatic tissue. Signup and view all the answers