16 Questions
What is the main function of the red pulp in the spleen?
Storage of red blood cells
Which component of the spleen is rich in lymphocytes and actively involved in immune responses?
White pulp
What type of tissue occupies the spaces between the trabeculae in the spleen?
Splenic pulp
Which cell type removes damaged erythrocytes from circulation in the spleen?
Macrophages
What structures extend from the capsule and hilus into the splenic parenchyma?
Trabeculae
Which layer of the spleen capsule consists of smooth muscle?
Inner layer
What are the venous channels found in the red pulp of the spleen called?
Sinusoids
What is the unique feature of the bursa of Fabricius in birds?
It is a saclike dorsal diverticulum of the proctodeum.
What is the structure of the follicles within the bursa of Fabricius?
They contain numerous polyhedral lymphatic tissue follicles.
What is the role of the bursa of Fabricius in B-cell differentiation?
It is functionally equivalent to the mammalian bone marrow.
At what stage of chicken embryo development do precursor cells committed to the B-cell lineage migrate into the developing bursa of Fabricius?
Day 8 to day 15 of development.
What is the process by which lymphatic nodules develop in the bursa of Fabricius?
They form as invaginations of the cloacal epithelium into underlying tissues.
What is the significance of the dichotomy of T- and B-cell lineages first being revealed in birds?
It demonstrates the unique features of the avian immune system.
What is the significance of the epithelial tuft of simple columnar cells covering the apex of each follicle in the bursa of Fabricius?
It is a specialized feature that is unique to the avian bursa of Fabricius.
What is the function of the capillary layer separating the cortex and medulla of the follicles in the bursa of Fabricius?
It provides nutrients and oxygen to the lymphatic tissue.
What is the significance of the pseudostratified columnar epithelium lining the bursa of Fabricius?
It provides structural support and protection for the underlying lymphatic tissue.
Learn about the two main types of red pulp present in mammalian spleens, based on the type of post-capillary vessels. Explore how domestic animals like dogs have venous sinuses similar to those in human and rat spleens, and the components of red pulp in the lymphatic system.
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