16 Questions
Where is the spleen located in the body?
Under the left costal margin
What gives rise to trabeculae and divides the parenchyma of the spleen into incomplete compartments?
Capsule
How does blood enter the spleen?
Through the splenic artery
Where are follicles containing B-cells found in the spleen?
Adjacent to the periarteriolar lymphatic sheath (PALS)
What is the function of the red pulp in the spleen?
Monitoring the integrity of red blood cells
What is unique about the blood circulation system in the spleen?
The majority of the arterioles end in cords without endothelial lining
In splenomegaly, which type of blood circulation becomes increasingly important?
Slow circulation
What surrounds the central arterioles in the white pulp of the spleen?
A core of lymphatic tissue known as white pulp
What is the composition of the red pulp of the spleen?
Splenic sinuses and splenic cords
What is particularly numerous in the vicinity of the sinusoids in the red pulp?
Macrophages
Which component separates the white pulp from the red pulp of the spleen?
Marginal zone
What is one of the functions of the spleen related to phagocytosis?
Removal of red cells containing excess DNA
Where is the tropical splenomegaly syndrome (TSS) predominantly found?
Malarious zones of the tropics
Which age groups are considered high-risk for prophylactic oral penicillin?
Less than 16 years and greater than 50 years
What is the recommended prophylactic treatment for hyposplenic patients?
Oral penicillin usually for life
Which vaccinations are recommended for hyposplenic individuals to prevent infection?
Pneumococcus, haemophilus, meningococcus, and influenza
This quiz provides an overview of the anatomy of the spleen, covering the composition of red pulp, including splenic sinuses and splenic cords (of Billroth), and the structure of white pulp. It also discusses the presence of macrophages in the vicinity of the sinusoids.
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