CH 5: Mutations

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Questions and Answers

What causes Sickle Cell Anaemia?

  • A recessive gene mutation affecting melanin production
  • Abnormal separation of chromosomes during Anaphase I
  • An extra chromosome 21
  • A faulty haemoglobin molecule due to a gene mutation (correct)

How does Albinism affect individuals?

  • By causing abnormal red blood cells
  • By blocking capillaries
  • By affecting skin, hair, and eye color due to a melanin deficiency (correct)
  • By altering chromosome numbers

Which phase of cell division can result in chromosome aberrations like Down syndrome?

  • Telophase II
  • Anaphase I (correct)
  • Anaphase II
  • Metaphase I

What is the cause of Down syndrome?

<p>Non-disjunction of chromosome pair 21 during meiosis (D)</p> Signup and view all the answers

How do chromosomal aberrations affect gametes?

<p>By producing extra chromosomes in gametes (A)</p> Signup and view all the answers

Which type of mutation is characterized by changes to the DNA responsible for producing specific proteins?

<p>Harmful mutations (D)</p> Signup and view all the answers

What percentage of DNA is non-coding and often involved in harmless mutations?

<p>98.5% (C)</p> Signup and view all the answers

Which type of mutation is considered beneficial as it enhances the organism's survival chances?

<p>Useful mutations (C)</p> Signup and view all the answers

In what process do gene mutations occur if a base pair is added, omitted, or doubled up?

<p>DNA replication (D)</p> Signup and view all the answers

Which term describes the genetic variation that occurs due to advantageous gene mutations being passed on and contributing to natural selection?

<p>Survival of the fittest (A)</p> Signup and view all the answers

What type of mutation involves changes to non-coding DNA and does not affect the cell's structure or functioning?

<p>Neutral mutations (D)</p> Signup and view all the answers

Which mutation type leads to genetic disorders like haemophilia and sickle cell anaemia?

<p>Harmful mutations (C)</p> Signup and view all the answers

What are examples of harmless mutations mentioned in the text?

<p>Freckles, blonde hair, and baldness (C)</p> Signup and view all the answers

How do useful mutations contribute to natural selection?

<p>By enhancing survival chances and leading to advantageous genetic variation (B)</p> Signup and view all the answers

When do gene mutations occur, resulting in alterations to the base sequence in DNA?

<p>During DNA replication (B)</p> Signup and view all the answers

Which of the following is a sex-linked gene mutation mentioned in the text?

<p>Haemophilia (A)</p> Signup and view all the answers

What percentage of DNA constitutes non-coding DNA that often undergoes harmless mutations?

<p>~98.5% (D)</p> Signup and view all the answers

What type of gene mutation causes Sickle Cell Anaemia?

<p>Dominant gene mutation (A)</p> Signup and view all the answers

Which condition is caused by a gene mutation affecting the normal development of melanin?

<p>Chromosomal aberration (A)</p> Signup and view all the answers

During which phase of cell division can chromosome aberrations like Down syndrome occur?

<p>Prophase II (A)</p> Signup and view all the answers

What is the genetic consequence of non-disjunction during meiosis?

<p>Inversion of chromosomal segments (C)</p> Signup and view all the answers

Which term best describes the effect of faulty haemoglobin molecules in Sickle Cell Anaemia on red blood cells?

<p>Vasoconstriction (C)</p> Signup and view all the answers

How does a zygote develop Down syndrome according to the text?

<p>Via dominant gene mutations inherited from one parent (C)</p> Signup and view all the answers

Which characteristic is most commonly affected by Albinism?

<p>Digestive system function (C)</p> Signup and view all the answers

What is the main difference between harmless mutations and harmful mutations?

<p>Harmless mutations change non-coding DNA, while harmful mutations affect protein production. (A)</p> Signup and view all the answers

How do useful mutations contribute to advantageous genetic variation?

<p>By enhancing the organism's survival chances through beneficial traits. (B)</p> Signup and view all the answers

Which genetic condition is mentioned in the text as an example of a harmful mutation?

<p>Haemophilia (A)</p> Signup and view all the answers

What effect do harmful mutations have on an organism?

<p>Cause genetic disorders and affect overall health (D)</p> Signup and view all the answers

Which specific type of DNA is often involved in harmless mutations?

<p>Non-coding DNA (C)</p> Signup and view all the answers

What role do useful mutations play in natural selection?

<p>They enhance survival chances, allowing organisms to pass on beneficial traits. (A)</p> Signup and view all the answers

Which genetic condition is affected by sex-linked gene mutations?

<p>Colour-blindness (A)</p> Signup and view all the answers

What is the consequence of anaphase I not separating chromosomes properly during cell division?

<p>Generation of abnormal zygotes (B)</p> Signup and view all the answers

How does a mutation in the gene responsible for producing melanin manifest in individuals?

<p>Abnormal skin, hair, and eye color (B)</p> Signup and view all the answers

In Down syndrome, what is the genetic basis of the condition?

<p>Extra or missing chromosome 21 (A)</p> Signup and view all the answers

What effect does the production of faulty haemoglobin molecules have on red blood cells in Sickle Cell Anaemia?

<p>Abnormally shaped red blood cells (A)</p> Signup and view all the answers

What type of mutation is characterized by an alteration in the DNA sequence that does not affect the structure or function of the cell?

<p>Silent mutation (C)</p> Signup and view all the answers

How do chromosome aberrations like Down syndrome affect zygotes?

<p>Result in chromosomal imbalance (D)</p> Signup and view all the answers

What is the outcome of a recessive gene mutation that inhibits melanin development in individuals?

<p>Albinism (A)</p> Signup and view all the answers

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