CH 5: Mutations
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Questions and Answers

What causes Sickle Cell Anaemia?

  • A recessive gene mutation affecting melanin production
  • Abnormal separation of chromosomes during Anaphase I
  • An extra chromosome 21
  • A faulty haemoglobin molecule due to a gene mutation (correct)
  • How does Albinism affect individuals?

  • By causing abnormal red blood cells
  • By blocking capillaries
  • By affecting skin, hair, and eye color due to a melanin deficiency (correct)
  • By altering chromosome numbers
  • Which phase of cell division can result in chromosome aberrations like Down syndrome?

  • Telophase II
  • Anaphase I (correct)
  • Anaphase II
  • Metaphase I
  • What is the cause of Down syndrome?

    <p>Non-disjunction of chromosome pair 21 during meiosis</p> Signup and view all the answers

    How do chromosomal aberrations affect gametes?

    <p>By producing extra chromosomes in gametes</p> Signup and view all the answers

    Which type of mutation is characterized by changes to the DNA responsible for producing specific proteins?

    <p>Harmful mutations</p> Signup and view all the answers

    What percentage of DNA is non-coding and often involved in harmless mutations?

    <p>98.5%</p> Signup and view all the answers

    Which type of mutation is considered beneficial as it enhances the organism's survival chances?

    <p>Useful mutations</p> Signup and view all the answers

    In what process do gene mutations occur if a base pair is added, omitted, or doubled up?

    <p>DNA replication</p> Signup and view all the answers

    Which term describes the genetic variation that occurs due to advantageous gene mutations being passed on and contributing to natural selection?

    <p>Survival of the fittest</p> Signup and view all the answers

    What type of mutation involves changes to non-coding DNA and does not affect the cell's structure or functioning?

    <p>Neutral mutations</p> Signup and view all the answers

    Which mutation type leads to genetic disorders like haemophilia and sickle cell anaemia?

    <p>Harmful mutations</p> Signup and view all the answers

    What are examples of harmless mutations mentioned in the text?

    <p>Freckles, blonde hair, and baldness</p> Signup and view all the answers

    How do useful mutations contribute to natural selection?

    <p>By enhancing survival chances and leading to advantageous genetic variation</p> Signup and view all the answers

    When do gene mutations occur, resulting in alterations to the base sequence in DNA?

    <p>During DNA replication</p> Signup and view all the answers

    Which of the following is a sex-linked gene mutation mentioned in the text?

    <p>Haemophilia</p> Signup and view all the answers

    What percentage of DNA constitutes non-coding DNA that often undergoes harmless mutations?

    <p>~98.5%</p> Signup and view all the answers

    What type of gene mutation causes Sickle Cell Anaemia?

    <p>Dominant gene mutation</p> Signup and view all the answers

    Which condition is caused by a gene mutation affecting the normal development of melanin?

    <p>Chromosomal aberration</p> Signup and view all the answers

    During which phase of cell division can chromosome aberrations like Down syndrome occur?

    <p>Prophase II</p> Signup and view all the answers

    What is the genetic consequence of non-disjunction during meiosis?

    <p>Inversion of chromosomal segments</p> Signup and view all the answers

    Which term best describes the effect of faulty haemoglobin molecules in Sickle Cell Anaemia on red blood cells?

    <p>Vasoconstriction</p> Signup and view all the answers

    How does a zygote develop Down syndrome according to the text?

    <p>Via dominant gene mutations inherited from one parent</p> Signup and view all the answers

    Which characteristic is most commonly affected by Albinism?

    <p>Digestive system function</p> Signup and view all the answers

    What is the main difference between harmless mutations and harmful mutations?

    <p>Harmless mutations change non-coding DNA, while harmful mutations affect protein production.</p> Signup and view all the answers

    How do useful mutations contribute to advantageous genetic variation?

    <p>By enhancing the organism's survival chances through beneficial traits.</p> Signup and view all the answers

    Which genetic condition is mentioned in the text as an example of a harmful mutation?

    <p>Haemophilia</p> Signup and view all the answers

    What effect do harmful mutations have on an organism?

    <p>Cause genetic disorders and affect overall health</p> Signup and view all the answers

    Which specific type of DNA is often involved in harmless mutations?

    <p>Non-coding DNA</p> Signup and view all the answers

    What role do useful mutations play in natural selection?

    <p>They enhance survival chances, allowing organisms to pass on beneficial traits.</p> Signup and view all the answers

    Which genetic condition is affected by sex-linked gene mutations?

    <p>Colour-blindness</p> Signup and view all the answers

    What is the consequence of anaphase I not separating chromosomes properly during cell division?

    <p>Generation of abnormal zygotes</p> Signup and view all the answers

    How does a mutation in the gene responsible for producing melanin manifest in individuals?

    <p>Abnormal skin, hair, and eye color</p> Signup and view all the answers

    In Down syndrome, what is the genetic basis of the condition?

    <p>Extra or missing chromosome 21</p> Signup and view all the answers

    What effect does the production of faulty haemoglobin molecules have on red blood cells in Sickle Cell Anaemia?

    <p>Abnormally shaped red blood cells</p> Signup and view all the answers

    What type of mutation is characterized by an alteration in the DNA sequence that does not affect the structure or function of the cell?

    <p>Silent mutation</p> Signup and view all the answers

    How do chromosome aberrations like Down syndrome affect zygotes?

    <p>Result in chromosomal imbalance</p> Signup and view all the answers

    What is the outcome of a recessive gene mutation that inhibits melanin development in individuals?

    <p>Albinism</p> Signup and view all the answers

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