12 Questions
Which of the following best describes the permanence of heterochromatin silencing?
Heterochromatin silencing is not necessarily permanent due to reversible modifications.
What do T cell receptors (TCRs) recognize?
Antigens presented by major histocompatibility complex (MHC) molecules
Do protein recognition receptors exhibit specificity in antigen recognition?
Yes, they exhibit specificity in recognizing antigen patterns or structures.
How is X inactivation in human females mediated?
By long non-coding RNAs (lncRNAs) like XIST
What is the purpose of Chromatin immunoprecipitation coupled with sequencing (ChIP-seq)?
To map the genomic regions bound by specific transcription factors
What role do maternal effect genes play in embryos?
Influencing early embryonic development and specifying the body axis
Do prokaryotes possess non-coding RNAs (ncRNAs)?
Yes, they are involved in various cellular processes including gene expression regulation
If a gene knockout leads to lethality in an animal model, what does it indicate about the gene?
The gene is essential for normal development or physiological function
What is the main characteristic of heterochromatin?
It is transcriptionally inactive
What type of DNA sequences does constitutive heterochromatin typically contain?
Repetitive DNA sequences
What role does facultative heterochromatin play in gene expression?
Regulating gene expression during development and in response to environmental cues
What contributes to the transcriptional repression of genes within heterochromatic regions?
Binding of histone proteins and specific histone modifications
Explore the characteristics and functions of heterochromatin, with a focus on constitutive heterochromatin. Learn about its condensed and transcriptionally inactive state, as well as its involvement in maintaining the structural integrity of chromosomes.
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