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18 Questions

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Type IV Pili in Bacteria Quiz

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Questions and Answers

Which type of pili are found in bacteria such as P.aeruginosa and N.gonorrhoeae?

Type III pili

Type I pili

Type IV pili (correct)

Type II pili

What do type IV pili bind to on epithelial cell surfaces?

Carbohydrates

Proteins

Glycolipids (correct)

Nucleic acids

Which term describes the surface proteins that bind to specific receptor molecules on host cells?

Enzymes

Flagella

Adhesins (correct)

Pili

What do MSCRAMMs stand for in the context of bacterial adhesion?

Microbial surface components recognising adhesive matrix molecules Signup and view all the answers

Which mechanism is involved in the binding of MSCRAMMs to their ligands?

'Dock lock latch' Signup and view all the answers

What is the role of type IV pili in Pseudomonas and Neisseria according to the text?

Biofilm formation Signup and view all the answers

Why is adhesion critical for bacterial pathogens?

To evade immune defenses and adhere to different cell types Signup and view all the answers

What is the purpose of pili (fimbriae) in host cell adherence?

To depolymerize and make intimate contact with host cells Signup and view all the answers

What is the role of adhesins in biofilm formation?

To serve as a trigger for synthesizing additional cell wall adhesins Signup and view all the answers

What makes biofilms more resistant to antibiotics and immune defenses compared to planktonic bacteria?

Formation of multicellular communities Signup and view all the answers

Why do bacteria constantly lose and reform pili?

To evade immune defenses by switching adhesive tips Signup and view all the answers

What is the function of the shaft end of pili in host cell adherence?

Attaching to specific receptors on host cells Signup and view all the answers

What is the role of the FimH adhesin in UPEC?

Recognizes mannose on mannosylated proteins of the bladder epithelium Signup and view all the answers

Which statement about the fim operon in UPEC is true?

Encodes type 1 pili and expresses hemagglutinin Signup and view all the answers

What is the function of PapG in P pili of UPEC?

Represents the actual adhesin Signup and view all the answers

Which statement accurately describes Type IV pili?

Enable twitching motility along a solid surface Signup and view all the answers

What happens when mutants lack type 1 pili or FimH adhesin in UPEC?

They are quickly cleared from the bladder Signup and view all the answers

What is the primary function of the PapK subunit in P pili of UPEC?

Connects above subunits to the PapA pilus rod Signup and view all the answers