18 Questions
What happens if there is a nutrition deficiency during pregnancy?
Increased sympathetic tone in the baby
How can certain bacteria in the gut affect food absorption?
Alter GLT-1 secretion
Which factor may damage the β-cells or their mitochondria?
Presence of reactive oxygen species
What is the role of kidneys in normal sugar metabolism?
Filter and reabsorb sugar only during fasting state
What causes diabetes according to the text?
Genes inherited and switched on
What is the basis for medications used for diabetes?
Egregious 11 considerations
What is the relationship between pancreatic beta cell function and pancreatic mass?
Increased pancreatic mass leads to increased beta cell function.
Which of the following defects is NOT part of the 'Egregious Eleven' related to Diabetes?
Pancreatic alpha cells
How does a destroyed safety center in the brain impact beta cell function?
It enhances beta cell function by increasing insulin production.
Which body organ is NOT mentioned as a site of gene manifestation in diabetic presentations?
Heart
What role do pro-diabetic genes play in the development of diabetes?
They need to be switched on to manifest diabetes later in life.
How does the size of the pancreatic mass affect insulin production?
Larger mass leads to more insulin production.
What is the main cause of complications in diabetes according to the text?
Excess fuel leading to release of reactive oxygen species (ROS)
Which of the following is NOT mentioned as a pathway activated by reactive oxygen species (ROS) in diabetes?
Acid reflux
What physiological manifestations can result from gene transcription favoring cell hypertrophy and apoptosis in diabetes?
Coronary artery disease, peripheral artery disease, retinopathy, and kidney impairment
Which one of the following is NOT a medication class mentioned in the text for diabetes management?
Lactate/pyruvate inhibitors
What is one of the pathways activated by reactive oxygen species (ROS) mentioned in the text that can lead to inflammation in diabetes?
Hexosamine flux
Which type of modulation is NOT mentioned in the text as a result of reactive oxygen species (ROS) activation in diabetes?
MicroRNA degradation
This quiz covers the impact of Diabetes Mellitus type 3 on the appetite center, dopamine surge, and the consequences of nutrition deficiency during pregnancy. It also delves into the role of gut bacteria in altering food absorption, inhibiting GLT-1 production, and the process of fecal transplantation. Additionally, it explores immune dysregulation and inflammation.
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