WK 11: Pathophysiology of Type 1 Diabetes
30 Questions
0 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

Which cell type is responsible for the destruction of beta cells in Type 1 Diabetes Mellitus?

  • B cells
  • Natural killer cells
  • Macrophages
  • Cytotoxic T cells (correct)

    • What is the significance of antibodies to the pancreas in the context of Type 1 Diabetes Mellitus?

  • They are responsible for diabetes onset
  • They are precluded in older individuals
  • They are a surrogate marker of disease process (correct)
  • They cause beta cell destruction

    • Which of the following populations has the highest risk for developing Type 1 Diabetes Mellitus?

  • Monozygotic twins (correct)
  • Dizygotic twins
  • Second-degree relatives
  • Individuals with no family history of the disease

    • Which of the following symptoms is more likely to present in older individuals with Type 1 Diabetes Mellitus?

    <p>Weight loss</p> Signup and view all the answers

    What is a key management goal for Type 1 Diabetes Mellitus?

    <p>Avoiding complications</p> Signup and view all the answers

    Which study is known for evaluating Diabetes Control and Complications in Type 1 Diabetes Mellitus?

    <p>DCCT</p> Signup and view all the answers

    What is one of the important aspects to consider in the management of severely insulin deficient Type 1 Diabetes Mellitus?

    <p>Insulin Pump Therapy</p> Signup and view all the answers

    What is the underlying cause of Type 1 Diabetes Mellitus?

    <p>Autoimmune destruction of beta cells</p> Signup and view all the answers

    What is a characteristic of Type 1 Diabetes Mellitus in children?

    <p>All presentations before 6 months are genetic in origin</p> Signup and view all the answers

    What is the goal of management in Type 1 Diabetes Mellitus?

    <p>To achieve near-normal blood glucose levels</p> Signup and view all the answers

    What is an available management option for patients with Type 1 Diabetes Mellitus?

    <p>Insulin Pump Therapy</p> Signup and view all the answers

    What is a challenge in the diagnosis of Type 1 Diabetes Mellitus?

    <p>Differentiating it from Type 2 Diabetes</p> Signup and view all the answers

    What is an implication of the heterogenous nature of Type 1 Diabetes?

    <p>We are moving towards a spectrum of diabetes classification</p> Signup and view all the answers

    What is essential for patients with Type 1 Diabetes Mellitus?

    <p>Diabetes education</p> Signup and view all the answers

    Which of the following is true about carbohydrate counting in Type 1 Diabetes Mellitus?

    <p>The CHO ratio is used to calculate the amount of insulin required to cover carbohydrates.</p> Signup and view all the answers

    What is the function of glucogenic amino acids in the body?

    <p>They are turned into alpha ketoacids which are further converted into glucose.</p> Signup and view all the answers

    Which of the following is a correct statement about insulin pump therapy for Type 1 Diabetes Mellitus?

    <p>It helps in achieving a flexible patient-controlled basal bolus regimen.</p> Signup and view all the answers

    In Type 1 Diabetes Mellitus, which amino acids are both glucogenic and ketogenic?

    <p>Isoleucine, Phenylalanine, Tyrosine, Threonine, Tryptophan</p> Signup and view all the answers

    What is the energy density of fat in comparison to carbohydrates?

    <p>Fat is more energy-dense than carbohydrates.</p> Signup and view all the answers

    Which treatment option is referred to as the 'artificial pancreas'?

    <p>Insulin pump therapy</p> Signup and view all the answers

    What is the cornerstone of therapy when managing Type 1 Diabetes Mellitus?

    <p>Carbohydrate counting</p> Signup and view all the answers

    In type 1 diabetes mellitus, which of the following is responsible for the genetic defects in pathways of insulin synthesis, processing, and signaling?

    <p>B-cells</p> Signup and view all the answers

    What glucose level is indicative of a diagnosis of diabetes mellitus in terms of 2-hour glucose levels?

    <p>≥ 11.1 mmol/L</p> Signup and view all the answers

    What is the term Arataeus used to describe diabetes mellitus due to the presence of sweetness in the urine?

    <p>Mellitus</p> Signup and view all the answers

    What physiological response occurs to fasting as described in the text?

    <p>Lipolysis and Ketogenesis</p> Signup and view all the answers

    Which of the following nutrients is mentioned as an alternative fuel source in prolonged fasts?

    <p>Ketones</p> Signup and view all the answers

    What system is responsible for a specific immune response to an immune trigger like an antigen?

    <p>Innate immune system</p> Signup and view all the answers

    What is the term used to describe the balance in the immune system between recognizing non-self antigens and self-antigens?

    <p>Tolerance</p> Signup and view all the answers

    Insulin is secreted in response to caloric consumption in how many phases as mentioned in the text?

    <p>2 phases</p> Signup and view all the answers

    Which of the following is NOT an action of insulin mentioned in the text?

    <p>Increasing ketogenesis</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser