Podcast
Questions and Answers
What is the epitope targeted by T cells in Type 1 diabetes?
What is the epitope targeted by T cells in Type 1 diabetes?
- insB:9–23 (correct)
- insC:12–27
- insA:5–18
- insD:3–15
Which peptide from Parabacteroides distasonis activated T cells specific to insB:9–23 in T1D patients and NOD mice?
Which peptide from Parabacteroides distasonis activated T cells specific to insB:9–23 in T1D patients and NOD mice?
- lmnopq7-25
- abcde5-20
- hprt4–18 (correct)
- xyzt3-15
What effect did colonization with P. distasonis have on the development of T1D in female NOD mice?
What effect did colonization with P. distasonis have on the development of T1D in female NOD mice?
- Prevented the development of T1D
- Delayed the development of T1D
- Accelerated the development of T1D (correct)
- Had no effect on the development of T1D
What was observed in the sera of NOD mice colonized with P. distasonis and human T1D patients?
What was observed in the sera of NOD mice colonized with P. distasonis and human T1D patients?
What effect did colonization with P. distasonis have on the development of T1D in female NOD mice?
What effect did colonization with P. distasonis have on the development of T1D in female NOD mice?
What is the epitope targeted by T cells in Type 1 diabetes?
What is the epitope targeted by T cells in Type 1 diabetes?
Which peptide from Parabacteroides distasonis activated T cells specific to insB:9–23 in T1D patients and NOD mice?
Which peptide from Parabacteroides distasonis activated T cells specific to insB:9–23 in T1D patients and NOD mice?
What was observed in the sera of NOD mice colonized with P. distasonis and human T1D patients?
What was observed in the sera of NOD mice colonized with P. distasonis and human T1D patients?
Which cell type decreased in female NOD mice colonized with P. distasonis, contributing to the acceleration of T1D development?
Which cell type decreased in female NOD mice colonized with P. distasonis, contributing to the acceleration of T1D development?
What was the effect of adoptive transfer of splenocytes from P. distasonis–treated mice to NOD/SCID mice?
What was the effect of adoptive transfer of splenocytes from P. distasonis–treated mice to NOD/SCID mice?
What was identified in the sera of NOD mice colonized with P. distasonis and human T1D patients?
What was identified in the sera of NOD mice colonized with P. distasonis and human T1D patients?
Which peptide from Parabacteroides distasonis activated T cells specific to insB:9–23 in T1D patients and NOD mice?
Which peptide from Parabacteroides distasonis activated T cells specific to insB:9–23 in T1D patients and NOD mice?
